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PDB: 49 件
6KYZ
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HRV14 3C in complex with single chain antibody YDF
分子名称: Genome polyprotein, YDF H chain, YDF L chain
著者Meng, B, Yang, B, Wilson, I.A.
登録日2019-09-20
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
5W3M
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BU of 5w3m by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle)
分子名称: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
著者Liu, Y, Dong, Y, Rossmann, M.G.
登録日2017-06-08
公開日2017-07-12
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6KZ0
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HRV14 3C in complex with single chain antibody GGVV
分子名称: GGVV H chain, GGVV L chain, Genome polyprotein
著者Meng, B, Yang, B, Wilson, I.A.
登録日2019-09-21
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BG7
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BU of 7bg7 by Molmil
HRV14 in complex with its receptor ICAM-1
分子名称: Genome polyprotein, Intercellular adhesion molecule 1
著者Hrebik, D, Fuzik, T, Plevka, P.
登録日2021-01-06
公開日2021-05-19
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating.
Proc.Natl.Acad.Sci.USA, 118, 2021
1NCQ
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The structure of HRV14 when complexed with pleconaril, an antiviral compound
分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
著者Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G.
登録日2002-12-05
公開日2003-12-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
5W3E
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BU of 5w3e by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle)
分子名称: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
著者Liu, Y, Dong, Y, Rossmann, M.G.
登録日2017-06-07
公開日2017-07-12
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7BG6
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HRV14 native particle solved by cryoEM
分子名称: Genome polyprotein, RNA-octamer (5'-R(P*UP*GP*UP*UP*UP*UP*UP*A)-3')
著者Hrebik, D, Fuzik, T, Plevka, P.
登録日2021-01-06
公開日2021-05-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating.
Proc.Natl.Acad.Sci.USA, 118, 2021
1K5M
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Crystal Structure of a Human Rhinovirus Type 14:Human Immunodeficiency Virus Type 1 V3 Loop Chimeric Virus MN-III-2
分子名称: CHIMERA OF HRV14 COAT PROTEIN VP2 (P1B) AND the V3 loop of HIV-1 gp120, COAT PROTEIN VP1 (P1D), COAT PROTEIN VP3 (P1C), ...
著者Ding, J, Smith, A.D, Geisler, S.C, Ma, X, Arnold, G.F, Arnold, E.
登録日2001-10-11
公開日2002-07-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of a Human Rhinovirus that Displays Part of the HIV-1 V3 Loop and Induces Neutralizing Antibodies against HIV-1
Structure, 10, 2002
5W3L
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CryoEM structure of rhinovirus B14 in complex with C5 Fab (4 degrees Celsius, molar ratio 1:3, full particle)
分子名称: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
著者Liu, Y, Dong, Y, Rossmann, M.G.
登録日2017-06-08
公開日2017-07-12
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7NUQ
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Rhinovirus 14 virion-like at pH 6.2
分子名称: Genome polyprotein, Octanucleotide
著者Hrebik, D, Plevka, P.
登録日2021-03-12
公開日2021-05-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating.
Proc.Natl.Acad.Sci.USA, 118, 2021
1XR5
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BU of 1xr5 by Molmil
Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14
分子名称: Genome polyprotein, SAMARIUM (III) ION
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
6HLT
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BU of 6hlt by Molmil
Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of rhinovirus-14 (HRV14)
分子名称: Genome polyprotein, Golgi resident protein GCP60
著者Klima, M, Boura, E.
登録日2018-09-11
公開日2019-07-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.815 Å)
主引用文献Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites.
Plos Pathog., 15, 2019
1R09
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BU of 1r09 by Molmil
HUMAN RHINOVIRUS 14 COMPLEXED WITH ANTIVIRAL COMPOUND R 61837
分子名称: 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE, DIMETHYL SULFOXIDE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), ...
著者Chapman, M.S, Minor, I, Rossmann, M.G, Diana, G.D, Andries, K.
登録日1990-05-04
公開日1991-10-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human rhinovirus 14 complexed with antiviral compound R 61837.
J.Mol.Biol., 217, 1991
1RUF
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RHINOVIRUS 14 (HRV14) (MUTANT WITH ASN 1 219 REPLACED BY ALA (N219A IN CHAIN 1)
分子名称: RHINOVIRUS 14
著者Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G.
登録日1995-06-09
公開日1995-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUE
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RHINOVIRUS 14 SITE DIRECTED MUTANT N1219A COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14
著者Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G.
登録日1995-06-09
公開日1995-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUD
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BU of 1rud by Molmil
RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
分子名称: 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14
著者Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G.
登録日1995-06-09
公開日1995-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1R08
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-(HYDROXYETHYL OXYMETHYLENEOXYMETHYL) ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2HWB
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BU of 2hwb by Molmil
A comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
分子名称: 5-(3-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PROPYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Kim, K.H, Rossmann, M.G.
登録日1994-01-25
公開日1994-11-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWC
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Kim, K.H, Rossmann, M.G.
登録日1994-01-25
公開日1994-11-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
4PDW
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A benzonitrile analogue inhibits rhinovirus replication
分子名称: 4-[(4,5-dimethoxy-2-nitrophenyl)acetyl]benzonitrile, Capsid protein VP4/VP2, GLYCEROL, ...
著者Querol-Audi, J, Guerra, P, Lacroix, C, Roche, M, Franco, D, Froeyen, M, Terme, T, Vanelle, P, Neyts, J, Leyssen, P, Verdaguer, N.
登録日2014-04-22
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A novel benzonitrile analogue inhibits rhinovirus replication.
J.Antimicrob.Chemother., 69, 2014
1RUG
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BU of 1rug by Molmil
RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14
著者Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G.
登録日1995-06-09
公開日1995-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
2RM2
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(7-(6-CHLORO-4-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RS3
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(7-(5-HYDRO-4-ETHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2RMU
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THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14
分子名称: HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
著者Badger, J, Krishnaswamy, S, Kremer, M.J, Oliveira, M.A, Rossmann, M.G, Heinz, B.A, Rueckert, R.R, Dutko, F.J, Mckinlay, M.A.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Three-dimensional structures of drug-resistant mutants of human rhinovirus 14.
J.Mol.Biol., 207, 1989
2RS5
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STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(5-(4-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989

 

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