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PDB: 459 件

5H5U
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Mechanistic insights into the alternative translation termination by ArfA and RF2
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N.
登録日2016-11-09
公開日2017-01-25
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
6ZTP
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E. coli 70S-RNAP expressome complex in uncoupled state 6
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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E. coli 70S-RNAP expressome complex in uncoupled state 2
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-21
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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E. coli 70S-RNAP expressome complex in uncoupled state 1
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
7Q4K
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Erythromycin-stalled Escherichia coli 70S ribosome with streptococcal MsrDL nascent chain
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fostier, C.R, Ousalem, F, Soufari, H, Leroy, E.C, Ngo, S, Innis, A, Hashem, Y, Boel, G.
登録日2021-10-31
公開日2022-11-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Regulation of the macrolide resistance ABC-F translation factor MsrD.
Nat Commun, 14, 2023
5WFS
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-12
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
8AP4
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Structure of Escherischia coli heat shock protein Hsp15 in complex with ribosomal 50S subunits bearing peptidyl-tRNA
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Safdari, H.A, Wilson, D.N.
登録日2022-08-09
公開日2022-11-16
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of Escherichia coli heat shock protein Hsp15 in complex with the ribosomal 50S subunit bearing peptidyl-tRNA.
Nucleic Acids Res., 50, 2022
7ST6
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Pre translocation, non-rotated 70S ribosome (Structure I)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Carbone, C.E, Korostelev, A.A.
登録日2021-11-12
公開日2022-02-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
8B7Y
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Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Koller, T.O, Graf, M, Wilson, D.N.
登録日2022-10-03
公開日2023-01-25
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
7OIF
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CspA-27 cotranslational folding intermediate 2
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
登録日2021-05-11
公開日2022-01-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
7OII
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CspA-70 cotranslational folding intermediate 2
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
登録日2021-05-11
公開日2022-01-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
5J7L
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Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-06
公開日2016-07-27
最終更新日2018-08-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
6WDE
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure V-B)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WD0
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure I-A)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
8C8Y
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Cryo-EM captures early ribosome assembly in action
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Lauer, S, Nikolay, R, Qin, B.
登録日2023-01-21
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
5JC9
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Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-14
公開日2016-07-06
最終更新日2016-08-03
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
7NWW
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BU of 7nww by Molmil
CspA-27 cotranslational folding intermediate 1
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
登録日2021-03-17
公開日2022-01-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
6SZS
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Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Muller, C, Beckert, B, Wilson, D.N.
登録日2019-10-02
公開日2019-12-04
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis.
Nat Commun, 10, 2019
5MDW
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Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
登録日2016-11-13
公開日2016-12-14
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Translational termination without a stop codon.
Science, 354, 2016
7AC7
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Structure of accomodated trans-translation complex on E. Coli stalled ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R.
登録日2020-09-10
公開日2021-08-18
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structures of tmRNA and SmpB as they transit through the ribosome.
Nat Commun, 12, 2021
4WF1
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Crystal structure of the E. coli ribosome bound to negamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
登録日2014-09-11
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
8PKL
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Escherichia coli paused disome complex (leading 70S non-rotated closed PRE state)
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Fluegel, T, Schacherl, M.
登録日2023-06-26
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
4V7U
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Crystal structure of the E. coli ribosome bound to erythromycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4WWW
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BU of 4www by Molmil
Crystal structure of the E. coli ribosome bound to CEM-101
分子名称: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ...
著者Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S.
登録日2014-11-12
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.
Antimicrob. Agents Chemother., 54, 2010
7PJY
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Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N.
登録日2021-08-24
公開日2021-10-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural mechanism of GTPase-powered ribosome-tRNA movement.
Nat Commun, 12, 2021

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