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PDB: 204 件

3EIM
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Metal exchange in Thermolysin
分子名称: CALCIUM ION, COPPER (I) ION, GLYCEROL, ...
著者Englert, L, Heine, A, Klebe, G.
登録日2008-09-16
公開日2009-10-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Metal exchange in Thermolysin
To be Published
1TMN
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BU of 1tmn by Molmil
Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称: CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases
Biochemistry, 23, 1984
4D91
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BU of 4d91 by Molmil
Thermolysin In Complex With DMSO And Acetate
分子名称: ACETATE ION, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Biela, A, Heine, A, Klebe, G.
登録日2012-01-11
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermolysin Inhibition
To be Published
1KTO
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BU of 1kto by Molmil
Thermolysin complexed with Z-D-Alanine (benzyloxycarbonyl-D-Alanine)
分子名称: CALCIUM ION, D-ALANINE, Thermolysin, ...
著者Senda, M, Senda, T, Kidokoro, S.
登録日2002-01-17
公開日2003-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure analyses of thermolysin in complex with its inhibitors.
To be Published
1FJW
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BU of 1fjw by Molmil
THERMOLYSIN (50 MM PHENOL SOAKED)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, PHENOL, ...
著者English, A.C, Groom, C.R, Hubbard, R.E.
登録日2000-08-08
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
5O8N
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BU of 5o8n by Molmil
Structure of thermolysin at room temperature via a method of acoustically induced rotation.
分子名称: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Axford, D.N, Burton, C, Docker, P, Prince, M, Topham, P.D.
登録日2017-06-13
公開日2017-08-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An acoustic on-chip goniometer for room temperature macromolecular crystallography.
Lab Chip, 17, 2017
1LNA
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BU of 1lna by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CALCIUM ION, COBALT (II) ION, DIMETHYL SULFOXIDE, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
3FBO
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BU of 3fbo by Molmil
Metal exchange in Thermolysin
分子名称: CALCIUM ION, COPPER (II) ION, Thermolysin
著者Englert, L, Heine, A, Klebe, G.
登録日2008-11-19
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Metal exchange in thermolysin
To be Published
3FOR
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BU of 3for by Molmil
Thermolysin Complexed with BNPA (2-Benzyl-3-Nitro Propanoic Acid Amide)
分子名称: (2R)-2-benzyl-3-nitropropanamide, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Wang, S.-F, Jin, J.-Y, Tian, G.-R.
登録日2008-12-31
公開日2010-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Nitro as ZBG in the inhibition of Thermolysin
To be Published
3TLI
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BU of 3tli by Molmil
THERMOLYSIN (10% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-28
公開日2000-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
2TLI
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BU of 2tli by Molmil
THERMOLYSIN (5% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-28
公開日2000-02-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
3F2P
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BU of 3f2p by Molmil
Thermolysin inhibition
分子名称: 3-methyl-2-(propanoyloxy)benzoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Englert, L, Heine, A, Klebe, G.
登録日2008-10-30
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fragment-Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition.
Chemmedchem, 5, 2010
7TLI
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BU of 7tli by Molmil
THERMOLYSIN (90% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-30
公開日2000-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
3T2H
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BU of 3t2h by Molmil
Tetragonal thermolysin in the presence of TMAO
分子名称: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Cahn, J, Hti Lar Seng, N.S, Juers, D.
登録日2011-07-22
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
2WI0
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BU of 2wi0 by Molmil
Dipeptide Inhibitors of Thermolysin
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, LEUCINE, ...
著者Lund, B.A, Leiros, I, Leiros, H.-K.S.
登録日2009-05-07
公開日2010-05-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dipeptide Inhibitors of Thermolysin
To be Published
4TLI
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BU of 4tli by Molmil
THERMOLYSIN (25% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-29
公開日2000-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
3MSN
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BU of 3msn by Molmil
Crystal structure of Thermolysin in complex with N-methylurea
分子名称: CALCIUM ION, GLYCEROL, N-METHYLUREA, ...
著者Behnen, J, Heine, A, Klebe, G.
登録日2010-04-29
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Experimental and computational active site mapping as a starting point to fragment-based lead discovery.
Chemmedchem, 7, 2012
3FLF
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BU of 3flf by Molmil
Thermolysin inhibition
分子名称: CALCIUM ION, GLYCEROL, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-valyl-L-leucine, ...
著者Englert, L, Biela, A, Heine, A, Klebe, G.
登録日2008-12-18
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Displacement of disordered water molecules from hydrophobic pocket creates enthalpic signature: binding of phosphonamidate to the S1'-pocket of thermolysin.
Biochim.Biophys.Acta, 1800, 2010
2G4Z
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BU of 2g4z by Molmil
anomalous substructure of thermolysin
分子名称: CALCIUM ION, CHLORIDE ION, SULFATE ION, ...
著者Mueller-Dieckmann, C, Weiss, M.S.
登録日2006-02-22
公開日2007-02-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
3LS7
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BU of 3ls7 by Molmil
Crystal structure of Thermolysin in complex with Xenon
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Behnen, J, Klebe, G, Heine, A, Brumshtein, B.
登録日2010-02-12
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Old acquantance rediscovered, use of xenon/protein complexes as a generic tool for SAD phasing of in house data
To be Published
1FJ3
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BU of 1fj3 by Molmil
THERMOLYSIN (50% ACETONE SOAKED)
分子名称: ACETONE, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者English, A.C, Groom, C.R, Hubbard, R.E.
登録日2000-08-07
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJU
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BU of 1fju by Molmil
THERMOLYSIN (80% ACETONITRILE SOAKED CRYSTALS)
分子名称: ACETONITRILE, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者English, A.C, Groom, C.R, Hubbard, R.E.
登録日2000-08-08
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJO
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BU of 1fjo by Molmil
THERMOLYSIN (60% ACETONE SOAKED CRYSTALS)
分子名称: ACETONE, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者English, A.C, Groom, C.R, Hubbard, R.E.
登録日2000-08-08
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJV
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BU of 1fjv by Molmil
THERMOLYSIN (60% ACETONITRILE SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, THERMOLYSIN, ...
著者English, A.C, Groom, C.R, Hubbard, R.E.
登録日2000-08-08
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
3T2J
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BU of 3t2j by Molmil
Tetragonal thermolysin in the presence of betaine
分子名称: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Cahn, J, Hti Lar Seng, N.S, Juers, D.
登録日2011-07-22
公開日2011-12-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012

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