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PDB: 32 件
1M4L
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STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G.
登録日2002-07-03
公開日2003-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Refined structure of bovine carboxypeptidase A at 1.25 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
3I1U
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Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based inactivator
分子名称: (2S,3R)-2-benzyl-3-sulfanylbutanoic acid, Carboxypeptidase A1 (Pancreatic), GLYCEROL, ...
著者Fernandez, D.
登録日2009-06-28
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献The X-ray structure of carboxypeptidase A inhibited by a thiirane mechanism-based inhibitor
Chem.Biol.Drug Des., 75, 2010
2CTC
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2CTB
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
1YME
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STRUCTURE OF CARBOXYPEPTIDASE
分子名称: CARBOXYPEPTIDASE A ALPHA, ZINC ION
著者Greenblatt, H.M, Tucker, P.A, Shoham, G.
登録日1996-07-15
公開日1997-02-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
5CPA
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REFINED CRYSTAL STRUCTURE OF CARBOXYPEPTIDASE A AT 1.54 ANGSTROMS RESOLUTION.
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Lipscomb, W.N.
登録日1982-05-06
公開日1982-07-29
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Refined crystal structure of carboxypeptidase A at 1.54 A resolution.
J.Mol.Biol., 168, 1983
1BAV
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CARBOXYPEPTIDASE A COMPLEXED WITH 2-BENZYL-3-IODO-PROPANOIC ACID (BIP)
分子名称: 2-BENZYL-3-IODOPROPANOIC ACID, CARBOXYPEPTIDASE A, ZINC ION
著者Martin, P, Edwards, B.
登録日1996-11-14
公開日1997-04-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic and computational insight on the mechanism of zinc-ion-dependent inactivation of carboxypeptidase a by 2-benzyl-3-iodopropanoate.
J.Am.Chem.Soc., 118, 1996
2RFH
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Crystal Structure Analysis of CPA-2-benzyl-3-nitropropanoic acid complex
分子名称: (2R)-2-benzyl-3-nitropropanoic acid, Carboxypeptidase A1, ZINC ION
著者Wang, S.-F, Zeng, Z.-H.
登録日2007-09-29
公開日2008-04-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A
Bioorg.Med.Chem., 16, 2008
1EE3
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Cadmium-substituted bovine pancreatic carboxypeptidase A (alfa-form) at pH 7.5 and 2 mM chloride in monoclinic crystal form
分子名称: CADMIUM ION, PROTEIN (CARBOXYPEPTIDASE A)
著者Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
登録日2000-01-30
公開日2002-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
3KGQ
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Carboxypeptidase A liganded to an organic small-molecule: conformational changes
分子名称: ACETONE, CITRIC ACID, Carboxypeptidase A1, ...
著者Fernandez, D, Boix, E, Pallares, I, Aviles, F.X, Vendrell, J.
登録日2009-10-29
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A
Enzyme Res, 2011, 2011
1ZLH
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Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
分子名称: Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor
著者Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
登録日2005-05-06
公開日2005-07-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1HDU
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BU of 1hdu by Molmil
Crystal structure of bovine pancreatic carboxypeptidase A complexed with aminocarbonylphenylalanine at 1.75 A
分子名称: CARBOXYPEPTIDASE A, D-[(AMINO)CARBONYL]PHENYLALANINE, ZINC ION
著者Cho, J.H, Ha, N.-C, Chung, S.J, Kim, D.H, Choi, K.Y, Oh, B.-H.
登録日2000-11-17
公開日2001-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
1HEE
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Crystal structure of bovine pancreatic carboxypeptidase A complexed with L-N-hydroxyaminocarbonyl phenylalanine at 2.3 A
分子名称: CARBOXYPEPTIDASE A, L-[(N-HYDROXYAMINO)CARBONYL]PHENYLALANINE, ZINC ION
著者Cho, J.H, Ha, N.-C, Chung, S.J, Kim, D.H, Choi, K.Y, Oh, B.-H.
登録日2000-11-22
公開日2001-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
1F57
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CARBOXYPEPTIDASE A COMPLEX WITH D-CYSTEINE AT 1.75 A
分子名称: CARBOXYPEPTIDASE A, D-CYSTEINE, ZINC ION
著者van Aalten, D.M, Chong, C.R, Joshua-Tor, L.
登録日2000-06-13
公開日2000-09-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
Biochemistry, 39, 2000
1ELL
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CADMIUM-SUBSTITUTED BOVINE PANCREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 7.5 AND 0.25 M CHLORIDE IN MONOCLINIC CRYSTAL FORM.
分子名称: CADMIUM ION, CARBOXYPEPTIDASE A
著者Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
登録日2000-03-14
公開日2002-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
1ARM
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CARBOXYPEPTIDASE A WITH ZN REPLACED BY HG
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, HG-CARBOXYPEPTIDASE A=ALPHA= (COX), ...
著者Greenblatt, H.M, Feinberg, H, Tucker, P.A, Shoham, G.
登録日1994-11-22
公開日1996-08-17
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
3FVL
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Crystallogic studies on the Complex of Carboxypeptidase A with inhibitors using alpha-hydroxy ketone as zinc-binding group
分子名称: (2R)-2-benzyl-5-hydroxy-4-oxopentanoic acid, Carboxypeptidase A1, ZINC ION
著者Wang, S.F, Jin, J.-Y, Tian, G.R.
登録日2009-01-16
公開日2010-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Optical 2-benzyl-5-hydroxy4oxopentanoic acids against carboxypeptidase A: Synthesis, kinetic evaluation and X-ray crystallographic study
CHIN.CHEM.LETT., 21, 2010
3FX6
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X-RAY crystallographic studies on the complex of carboxypeptidase A with the inhibitor using alpha-nitro ketone as the zinc-binding group
分子名称: (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid, Carboxypeptidase A1, ZINC ION
著者Wang, S.F, Jin, J.Y, Tian, G.R.
登録日2009-01-20
公開日2009-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Characterization of alpha-nitromethyl ketone as a new zinc-binding group based on structural analysis of its complex with carboxypeptidase A
Bioorg.Med.Chem.Lett., 19, 2009
1ARL
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CARBOXYPEPTIDASE A WITH ZN REMOVED
分子名称: APO-CARBOXYPEPTIDASE A=ALPHA= (COX)
著者Greenblatt, H.M, Feinberg, H, Tucker, P.A, Shoham, G.
登録日1994-11-22
公開日1996-08-01
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
3CPA
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X-RAY CRYSTALLOGRAPHIC INVESTIGATION OF SUBSTRATE BINDING TO CARBOXYPEPTIDASE A AT SUBZERO TEMPERATURE
分子名称: CARBOXYPEPTIDASE A, GLYCINE, TYROSINE, ...
著者Lipscomb, W.N.
登録日1982-03-24
公開日1982-07-29
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystallographic investigation of substrate binding to carboxypeptidase A at subzero temperature.
Proc.Natl.Acad.Sci.USA, 83, 1986
8CPA
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COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY
分子名称: CARBOXYPEPTIDASE A, O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE, ZINC ION
著者Kim, H, Lipscomb, W.N.
登録日1991-05-21
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography.
Biochemistry, 30, 1991
7CPA
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COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY
分子名称: CARBOXYPEPTIDASE A, O-((((N-PHENYL-METHOXY-CARBONYL)-PHENYL ALANYL-CARBONYL)AMINO)-ISOBUTYL)HYDROXY PHOSPHINYL)-3-PHENYLACETIC ACID, ZINC ION
著者Kim, H, Lipscomb, W.N.
登録日1991-05-21
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography.
Biochemistry, 30, 1991
1CBX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND THE BIPRODUCT ANALOG INHIBITOR L-BENZYLSUCCINATE AT 2.0 ANGSTROMS RESOLUTION
分子名称: CARBOXYPEPTIDASE A, L-BENZYLSUCCINIC ACID, ZINC ION
著者Mangani, S, Carloni, P, Orioli, P.
登録日1991-10-31
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the complex between carboxypeptidase A and the biproduct analog inhibitor L-benzylsuccinate at 2.0 A resolution.
J.Mol.Biol., 223, 1992
1ELM
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CADMIUM-SUBSTITUTED BOVINE PACREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 5.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM.
分子名称: CADMIUM ION, CARBOXYPEPTIDASE A
著者Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
登録日2000-03-14
公開日2002-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
1CPX
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BETA FORM OF CARBOXYPEPTIDASE A (RESIDUES 3-307) FROM BOVINE PANCREAS IN AN ORTHORHOMBIC CRYSTAL FORM WITH TWO ZINC IONS IN THE ACTIVE SITE.
分子名称: HYDROXIDE ION, PROTEIN (CARBOXYPEPTIDASE A), ZINC ION
著者Bukrinsky, J.T, Bjerrum, M.J, Kadziola, A.
登録日1998-07-27
公開日1998-08-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Native carboxypeptidase A in a new crystal environment reveals a different conformation of the important tyrosine 248.
Biochemistry, 37, 1998

 

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