3FVL
Crystallogic studies on the Complex of Carboxypeptidase A with inhibitors using alpha-hydroxy ketone as zinc-binding group
Summary for 3FVL
Entry DOI | 10.2210/pdb3fvl/pdb |
Descriptor | Carboxypeptidase A1, ZINC ION, (2R)-2-benzyl-5-hydroxy-4-oxopentanoic acid, ... (4 entities in total) |
Functional Keywords | carboxypeptidase a, alpha-hydroxy ketone, inhibitor, carboxypeptidase, hydrolase, metal-binding, metalloprotease, polymorphism, protease, secreted, zinc, zymogen |
Biological source | Bos taurus (Bovine) |
Cellular location | Secreted, extracellular space: P00730 |
Total number of polymer chains | 3 |
Total formula weight | 104373.30 |
Authors | Wang, S.F.,Jin, J.-Y.,Tian, G.R. (deposition date: 2009-01-16, release date: 2010-01-12, Last modification date: 2023-11-01) |
Primary citation | Wang, S.F.,Jin, J.-Y.,Zeng, Z.H.,Tian, G.R. Optical 2-benzyl-5-hydroxy4oxopentanoic acids against carboxypeptidase A: Synthesis, kinetic evaluation and X-ray crystallographic study CHIN.CHEM.LETT., 21:159-162, 2010 Cited by DOI: 10.1016/j.cclet.2009.09.005PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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