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PDB: 4 件

1PWA
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BU of 1pwa by Molmil
Crystal structure of Fibroblast Growth Factor 19
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ...
著者Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L.
登録日2003-07-01
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
2P23
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Crystal structure of human FGF19
分子名称: Fibroblast growth factor 19
著者Mohammadi, M.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
6KTR
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Crystal structure of fibroblast growth factor 19 in complex with Fab
分子名称: Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ...
著者Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J.
登録日2019-08-28
公開日2020-07-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.59775758 Å)
主引用文献Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.
Cancer Sci., 111, 2020
6NFJ
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Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
分子名称: Beta-klotho, Fibroblast growth factor 19, Nanobody 30
著者Kuzina, E, Schlessinger, J, Lee, S.
登録日2018-12-20
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structures of ligand-occupied beta-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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件を2024-07-10に公開中

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