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PDB: 6 件

3UVK
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BU of 3uvk by Molmil
Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL2
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase MLL2, SULFATE ION, ...
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
4ERQ
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X-ray structure of WDR5-MLL2 Win motif peptide binary complex
分子名称: Histone-lysine N-methyltransferase MLL2, WD repeat-containing protein 5
著者Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
登録日2012-04-20
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4Z4P
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Structure of the MLL4 SET Domain
分子名称: Histone-lysine N-methyltransferase 2D, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Zhang, Z, Mittal, A, Reid, J, Reich, S, Gamblin, S.J, Wilson, J.R.
登録日2015-04-02
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolving Catalytic Properties of the MLL Family SET Domain.
Structure, 23, 2015
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
分子名称: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
著者Zhang, Y, Zandian, M, Kutateladze, T.
登録日2024-02-27
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
6O7G
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Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
分子名称: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2019-03-07
公開日2019-05-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
8U2Y
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Solution structure of the PHD6 finger of MLL4 bound to TET3
分子名称: Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION
著者Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G.
登録日2023-09-06
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献MLL4 binds TET3.
Structure, 32, 2024

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件を2024-07-10に公開中

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