5GZC
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5GZD
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8CM8
| Galectin-8 N-terminal carbohydrate recognition domain in complex with 4-(bromophenyl)phthalazinone D-galactal ligand | 分子名称: | 4-(4-bromophenyl)-2-[[(2~{R},3~{R},4~{R})-2-(hydroxymethyl)-3-oxidanyl-3,4-dihydro-2~{H}-pyran-4-yl]oxymethyl]phthalazin-1-one, CHLORIDE ION, Galectin-8 | 著者 | Van Klaveren, S, Hakansson, M, Diehl, C, Nilsson, N.J. | 登録日 | 2023-02-17 | 公開日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Halogenated Galactal-Phenylphthalazinone Hybrids as Highly Selective Galectin-8N Ligands To Be Published
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5GZE
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3AP9
| Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with Lacto-N-fucopentaose III | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Galectin-8, ... | 著者 | Matsuzaka, T, Ideo, H, Yamashita, K, Nonaka, T. | 登録日 | 2010-10-12 | 公開日 | 2011-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans J.Biol.Chem., 286, 2011
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6Z6Y
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7ALS
| Alpha and beta Lactose isomer structure of Galectin 8, N-terminal domain | 分子名称: | CHLORIDE ION, Galectin-8, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Hakansson, M, Walse, B, Diehl, C, Kovacic, R. | 登録日 | 2020-10-07 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Alpha and beta Lactose isomer structure of Galectin 8, N-terminal domain To Be Published
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4BMB
| Crystal structure of the N terminal domain of human Galectin 8 | 分子名称: | GALECTIN-8, GLYCEROL, SODIUM ION, ... | 著者 | Buzamet, E, Ruiz, F.M, Menendez, M, Romero, A, Gabius, H.J, Solis, D. | 登録日 | 2013-05-07 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.351 Å) | 主引用文献 | Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells. FEBS J., 281, 2014
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7P1M
| Galectin-8 N-terminal carbohydrate recognition domain in complex with benzimidazole D-galactal ligand | 分子名称: | 2-[[(2R,3R,4R)-2-(hydroxymethyl)-3-oxidanyl-3,4-dihydro-2H-pyran-4-yl]oxymethyl]-3-methyl-benzimidazole-5-carboxylic acid, CHLORIDE ION, Galectin-8 | 著者 | Hassan, M, Hakansson, M, Nilsson, J.U, Kovacic, R. | 登録日 | 2021-07-02 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. Acs Med.Chem.Lett., 12, 2021
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3AP7
| Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with lactose sialic acid | 分子名称: | CHLORIDE ION, Galectin-8, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Matsuzaka, T, Ideo, H, Yamashita, K, Nonaka, T. | 登録日 | 2010-10-12 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans J.Biol.Chem., 286, 2011
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3AP6
| Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with lactose 3'-sulfate | 分子名称: | Galectin-8, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Matsuzaka, T, Ideo, H, Yamashita, K, Nonaka, T. | 登録日 | 2010-10-12 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans J.Biol.Chem., 286, 2011
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5T7U
| Crystal structure of galectin-8N in complex with Glycerol | 分子名称: | CHLORIDE ION, GLYCEROL, Galectin-8, ... | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | 登録日 | 2016-09-05 | 公開日 | 2017-01-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8. Sci Rep, 6, 2016
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6W4Z
| Galectin-8N terminal domain in complex with Methyl 3-O-[3-O-benzyloxy]-malonyl-beta-D-galactopyranoside | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Galectin-8, ... | 著者 | Patel, B, Kishor, C, Blanchard, H. | 登録日 | 2020-03-12 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Rational Design and Synthesis of Methyl-beta-d-galactomalonyl Phenyl Esters as Potent Galectin-8 N Antagonists. J.Med.Chem., 63, 2020
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8HL9
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7AEN
| Galectin-8 N-terminal carbohydrate recognition domain in complex with methyl 3-O-((7-carboxy)quinolin-2-yl)-methoxy)-beta-D-galactopyranoside | 分子名称: | CHLORIDE ION, GLYCEROL, Isoform 2 of Galectin-8, ... | 著者 | Hassan, M, Klavern, V.S, Hakansson, M, Anderluh, M, Tomasic, T, Jakopin, Z, Nilsson, J.U, Kovacic, R, Walse, B, Diehl, C. | 登録日 | 2020-09-17 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain Acs Med.Chem.Lett., 12, 2021
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5T7S
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3AP5
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2YV8
| Crystal structure of N-terminal domain of human galectin-8 | 分子名称: | Galectin-8 variant | 著者 | Kishishita, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-10 | 公開日 | 2008-04-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal structure of N-terminal domain of human galectin-8 To be Published
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3APB
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5T7T
| Galectin-8 N terminal domain in complex with LNT | 分子名称: | CHLORIDE ION, Galectin-8, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | 登録日 | 2016-09-05 | 公開日 | 2017-01-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8. Sci Rep, 6, 2016
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3VKN
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5GZG
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4BME
| Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant | 分子名称: | GALECTIN-8, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Buzamet, E, Ruiz, F.M, Menendez, M, Romero, A, Gabius, H.J, Solis, D. | 登録日 | 2013-05-07 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells. FEBS J., 281, 2014
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5T7I
| Crystal structure of galectin-8N in complex with LNnT | 分子名称: | Galectin-8, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | 登録日 | 2016-09-05 | 公開日 | 2017-01-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8. Sci Rep, 6, 2016
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5GZF
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