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PDB: 10 件

6G0Y
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BU of 6g0y by Molmil
X-ray structure of M-21 protein complex
分子名称: Matrix M2-1, Phosphoprotein, ZINC ION
著者Edwards, T.A, Barr, J.
登録日2018-03-20
公開日2018-11-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex.
Mbio, 9, 2018
8FPI
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BU of 8fpi by Molmil
Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1
分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L
著者Fischmann, T.O.
登録日2023-01-04
公開日2023-06-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Commun Biol, 6, 2023
4UCB
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N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
分子名称: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
著者Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
登録日2014-12-03
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
8FU3
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Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor
分子名称: 8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L
著者Yu, X, Abeywickrema, P, Bonneux, B, Behera, I, Jacoby, E, Fung, A, Adhikary, S, Bhaumik, A, Carbajo, R.J, Bruyn, S.D, Miller, R, Patrick, A, Pham, Q, Piassek, M, Verheyen, N, Shareef, A, Sutto-Ortiz, P, Ysebaert, N, Vlijmen, H.V, Jonckers, T.H.M, Herschke, F, McLellan, J.S, Decroly, E, Fearns, R, Grosse, S, Roymans, D, Sharma, S, Rigaux, P, Jin, Z.
登録日2023-01-16
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.
Commun Biol, 6, 2023
6PZK
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BU of 6pzk by Molmil
Cryo-EM Structure of the Respiratory Syncytial Virus Polymerase (L) Protein Bound by the Tetrameric Phosphoprotein (P)
分子名称: Phosphoprotein, RNA-directed RNA polymerase L
著者Gilman, M.S.A, McLellan, J.S.
登録日2019-08-01
公開日2019-09-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the Respiratory Syncytial Virus Polymerase Complex.
Cell, 179, 2019
4UCA
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BU of 4uca by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
分子名称: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
著者Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
登録日2014-12-03
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
8SNX
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Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the leader promoter
分子名称: Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*GP*CP*GP*U)-3'), RNA-directed RNA polymerase L
著者Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B.
登録日2023-04-28
公開日2023-12-20
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the promoter-bound respiratory syncytial virus polymerase.
Nature, 625, 2024
8SNY
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Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the trailer complementary promoter
分子名称: Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*UP*CP*GP*U)-3'), RNA-directed RNA polymerase L
著者Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B.
登録日2023-04-28
公開日2023-12-20
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structures of the promoter-bound respiratory syncytial virus polymerase.
Nature, 625, 2024
6UEN
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Cryo-EM structure of the respiratory syncytial virus RNA polymerase
分子名称: RNA-directed RNA polymerase L, the phosphoprotein (P) of human respiratory syncytial virus
著者Cao, D, Gao, Y, Liang, B.
登録日2019-09-22
公開日2020-01-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Cryo-EM structure of the respiratory syncytial virus RNA polymerase.
Nat Commun, 11, 2020
6YP5
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Solution NMR structure of the oligomerization domain of respiratory syncytial virus phosphoprotein
分子名称: Phosphoprotein
著者Cardone, C, Bontems, F, Bardiaux, B, Sizun, C.
登録日2020-04-15
公開日2021-04-28
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein.
Biomolecules, 11, 2021

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件を2024-07-31に公開中

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