7TR2
| Apo CaKip3[2-436]-L2-mutant(HsKHC) in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein,Kinesin-1 heavy chain, ... | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. | 登録日 | 2022-01-27 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
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6O5N
| Tubulin-RB3_SLD-TTL in complex with compound 10ab | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-03-04 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
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7DBD
| 444 in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Wu, C.Y, Wang, Y.X. | 登録日 | 2020-10-19 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | 主引用文献 | 444 in complex with tubulin To Be Published
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6DPU
| Undecorated GMPCPP microtubule | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Zhang, R, Nogales, E. | 登録日 | 2018-06-09 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7TR1
| CaKip3[2-436]-L2-mutant(HsKHC) - AMP-PNP in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein,Kinesin-1 heavy chain, ... | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. | 登録日 | 2022-01-27 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
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6CVJ
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6MZG
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6O2R
| Deacetylated Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | 登録日 | 2019-02-24 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6DPV
| Undecorated GDP microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Zhang, R, Nogales, E. | 登録日 | 2018-06-09 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7Z2B
| P. berghei kinesin-8B motor domain in AMPPNP state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-11-16 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7SGS
| Cryo-EM structure of full-length MAP7 bound to the microtubule | 分子名称: | Ensconsin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ferro, L.S, Fang, Q, Eshun-Wilson, L, Fernandes, J, Jack, A, Farrell, D.P, Golcuk, M, Huijben, T, Costa, K, Gur, M, DiMaio, F, Nogales, E, Yildiz, A. | 登録日 | 2021-10-07 | 公開日 | 2022-05-18 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7. Science, 375, 2022
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3JAK
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6BJC
| TPX2_mini decorated GMPCPP-microtubule | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Zhang, R, Nogales, E. | 登録日 | 2017-11-05 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into TPX2-stimulated microtubule assembly. Elife, 6, 2017
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6Y4M
| Structure of Tubulin Tyrosine Ligase in Complex with Tb111 | 分子名称: | (2~{R})-1-methylpiperidine-2-carboxylic acid, (2~{S},4~{R})-4-azanyl-2-methyl-5-phenyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Gavrilyuk, J, Nocek, B, Rigol, S, Nicolaou, K.C, Stoll, V. | 登録日 | 2020-02-21 | 公開日 | 2021-03-31 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. J.Org.Chem., 86, 2021
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7XQX
| Crystal structure of T2R-TTL-27a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-7-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Crystal structure of T2R-TT complex To Be Published
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3JAR
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5KMG
| Near-atomic cryo-EM structure of PRC1 bound to the microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. | 登録日 | 2016-06-27 | 公開日 | 2016-08-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proc.Natl.Acad.Sci.USA, 113, 2016
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6DPW
| Undecorated GTPgammaS microtubule | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Zhang, R, Nogales, E. | 登録日 | 2018-06-09 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7DN0
| AJ-GMPCPP-MT-non-seam | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Wang, Y.X. | 登録日 | 2020-12-08 | 公開日 | 2021-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | GMPCPP microtubule To Be Published
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7YSN
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5SYE
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5SYG
| Cryo-EM reconstruction of zampanolide-bound microtubule | 分子名称: | (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Kellogg, E.H, Hejab, N.M.A, Nogales, E. | 登録日 | 2016-08-11 | 公開日 | 2017-02-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
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5SYC
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3JAS
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3JAL
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