3H24
 
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3TYD
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4DAF
 | | Crystal structure of B. anthracis DHPS with compound 19 | | 分子名称: | (2R)-2-(7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid, Dihydropteroate Synthase, SULFATE ION | | 著者 | Hammoudeh, D, Lee, R.E, White, S.W. | | 登録日 | 2012-01-12 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity.
Chemmedchem, 7, 2012
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3TYB
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3H2C
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3TYA
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3H2O
 | | Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase | | 分子名称: | 4-{[2-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)ethyl]amino}benzoic acid, Dihydropteroate synthase, SULFATE ION | | 著者 | Yun, M.-K, White, S.W. | | 登録日 | 2009-04-14 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural studies of pterin-based inhibitors of dihydropteroate synthase.
J.Med.Chem., 53, 2010
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1TWZ
 | | Dihydropteroate Synthetase, With Bound Substrate Analogue PtP, From Bacillus anthracis | | 分子名称: | DHPS, Dihydropteroate synthase, PTERIN-6-YL-METHYL-MONOPHOSPHATE, ... | | 著者 | Babaoglu, K, Qi, J, Lee, R.L, White, S.W. | | 登録日 | 2004-07-01 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design.
STRUCTURE, 12, 2004
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