3H24
Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase
Summary for 3H24
Entry DOI | 10.2210/pdb3h24/pdb |
Related | 1TWS 1TWW 1TWZ 1TX0 1TX2 3H21 3H22 3H23 3H26 3H2A 3H2C 3H2E 3H2F 3H2M 3H2N 3H2O |
Descriptor | Dihydropteroate synthase, 2-amino-8-sulfanyl-1,9-dihydro-6H-purin-6-one, SULFATE ION, ... (4 entities in total) |
Functional Keywords | anthracis, folate biosynthesis, dihydropteroate, pterine, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Bacillus anthracis str. A2012 |
Total number of polymer chains | 2 |
Total formula weight | 67286.61 |
Authors | Yun, M.-K.,White, S.W. (deposition date: 2009-04-14, release date: 2009-12-08, Last modification date: 2023-09-06) |
Primary citation | Hevener, K.E.,Yun, M.K.,Qi, J.,Kerr, I.D.,Babaoglu, K.,Hurdle, J.G.,Balakrishna, K.,White, S.W.,Lee, R.E. Structural studies of pterin-based inhibitors of dihydropteroate synthase. J.Med.Chem., 53:166-177, 2010 Cited by PubMed: 19899766DOI: 10.1021/jm900861d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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