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PDB: 7 件
4G6C
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BU of 4g6c by Molmil
Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315
分子名称: Beta-hexosaminidase 1
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-07-18
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315
To be Published
4GNV
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BU of 4gnv by Molmil
Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315 with bound N-Acetyl-D-Glucosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase 1, CHLORIDE ION
著者SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-08-17
公開日2012-08-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315 with bound N-Acetyl-D-Glucosamine
TO BE PUBLISHED
4MSS
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BU of 4mss by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-acetamido-4,5,6-trihydroxyazepane
分子名称: Beta-hexosaminidase 1, GLYCEROL, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]acetamide
著者Vadlamani, G, Mark, B.L.
登録日2013-09-18
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams.
Chem.Commun.(Camb.), 49, 2013
6DTE
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BU of 6dte by Molmil
GlcNAc-inspired cyclophellitol bound to NagZ
分子名称: 2,2,2-trifluoro-N-[(1R,2R,3R,4R,5R,6R)-2,3,5,6-tetrahydroxy-4-(hydroxymethyl)cyclohexyl]acetamide, Beta-hexosaminidase
著者Mark, B.L, Winogrodzki, J.L.
登録日2018-06-15
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.929 Å)
主引用文献A mechanism-based GlcNAc-inspired cyclophellitol inactivator of the peptidoglycan recycling enzyme NagZ reverses resistance to beta-lactams in Pseudomonas aeruginosa.
Chem. Commun. (Camb.), 54, 2018
5UTR
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BU of 5utr by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane
分子名称: Beta-hexosaminidase, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]butanamide
著者Vadlamani, G, Mark, B.L.
登録日2017-02-15
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017
5UTQ
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BU of 5utq by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to PUGNAc
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-hexosaminidase, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
著者Vadlamani, G, Mark, B.L.
登録日2017-02-15
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017
5UTP
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BU of 5utp by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to N-ethylbutyryl-PUGNAc
分子名称: Beta-hexosaminidase, N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(phenylcarbamoyl)oxy]imino}tetrahydro-2H-pyran-3-yl]-2-ethylbutanamide
著者Vadlamani, G, Mark, B.L.
登録日2017-02-15
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017

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件を2024-07-10に公開中

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