8UWL
 
 | 5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM) | 分子名称: | 5-hydroxytryptamine receptor 2A, G protein subunit q (Gi2-mini-Gq chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Barros-Alvarez, X, Kim, K, Panova, O, Roth, B.L, Skiniotis, G. | 登録日 | 2023-11-06 | 公開日 | 2024-05-29 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | AlphaFold2 structures guide prospective ligand discovery. Science, 384, 2024
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8V6U
 
 | 5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking | 分子名称: | 4-{(3R)-1-[(1R)-1-(pyrimidin-2-yl)ethyl]piperidin-3-yl}phenol, 5-hydroxytryptamine receptor 2A, G protein alpha-subunit q (Gi2-mini-Gq chimera), ... | 著者 | Gumpper, R.H, Wang, L, Kapolka, N, Skiniotis, G, Roth, B.L. | 登録日 | 2023-12-03 | 公開日 | 2024-05-29 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | AlphaFold2 structures guide prospective ligand discovery. Science, 384, 2024
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