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PDB: 2 件

8UWL
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BU of 8uwl by Molmil
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
分子名称: 5-hydroxytryptamine receptor 2A, G protein subunit q (Gi2-mini-Gq chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Barros-Alvarez, X, Kim, K, Panova, O, Roth, B.L, Skiniotis, G.
登録日2023-11-06
公開日2024-05-29
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献AlphaFold2 structures guide prospective ligand discovery.
Science, 384, 2024
8V6U
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BU of 8v6u by Molmil
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
分子名称: 4-{(3R)-1-[(1R)-1-(pyrimidin-2-yl)ethyl]piperidin-3-yl}phenol, 5-hydroxytryptamine receptor 2A, G protein alpha-subunit q (Gi2-mini-Gq chimera), ...
著者Gumpper, R.H, Wang, L, Kapolka, N, Skiniotis, G, Roth, B.L.
登録日2023-12-03
公開日2024-05-29
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献AlphaFold2 structures guide prospective ligand discovery.
Science, 384, 2024

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件を2025-07-23に公開中

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