9GAO
 
 | | Crystal structure of CRBNmidi in complex with 2-(4-(2,6-dioxopiperidin-3-yl)phenoxy)-N-methylacetamide | | 分子名称: | 2-[4-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]phenoxy]-~{N}-methyl-ethanamide, Protein cereblon, ZINC ION | | 著者 | Rutter, Z.J, Kroupova, A, Zollman, D, Ciulli, A. | | 登録日 | 2024-07-29 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Nat Commun, 15, 2024
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8RQA
 | | Crystal structure of CRBN-midi in complex with Lenalidomide | | 分子名称: | Protein cereblon, S-Lenalidomide, ZINC ION | | 著者 | Rutter, Z.J, Kroupova, A, Zollman, D, Ciulli, A. | | 登録日 | 2024-01-17 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Nat Commun, 15, 2024
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8RQ9
 | | Crystal structure of PROTAC CFT-1297 in complex with CRBN-midi and BRD4(BD2) | | 分子名称: | (3~{S})-3-[7-[1-[7-[4-[6-(4-chlorophenyl)-1-methyl-spiro[[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4,1'-cyclopropane]-8-yl]pyrazol-1-yl]heptyl]piperidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]piperidine-2,6-dione, Bromodomain-containing protein 4, Protein cereblon, ... | | 著者 | Darren, D, Ramachandran, S, Kroupova, A, Zollman, D, Ciulli, A. | | 登録日 | 2024-01-17 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Nat Commun, 15, 2024
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8RQ1
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8RQC
 | | Crystal structure of CRBN-midi in complex with mezigdomide and IKZF1 ZF2 | | 分子名称: | DNA-binding protein Ikaros, Mezigdomide, Protein cereblon, ... | | 著者 | Furihata, H, Kroupova, A, Zollman, D, Ciulli, A. | | 登録日 | 2024-01-17 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Nat Commun, 15, 2024
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8RQ8
 | | Crystal structure of CRBN-midi in complex with mezigdomide | | 分子名称: | Mezigdomide, Protein cereblon, ZINC ION | | 著者 | Zollman, D, Kroupova, A, Pethe, J, Ciulli, A. | | 登録日 | 2024-01-17 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Nat Commun, 15, 2024
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