9BWT
| human sodium chloride cotransporter NCC S344E in the phosphorylation state and in complex with hydrochlorothiazide | 分子名称: | 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 3 | 著者 | Cao, E.H, Zhao, Y.X. | 登録日 | 2024-05-21 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases. Nat Commun, 15, 2024
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8VPP
| Phosphorylated human NCC in complex with chlorthalidone | 分子名称: | 2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide, Solute carrier family 12 member 3 | 著者 | Zhao, Y.X, Cao, E.H. | 登録日 | 2024-01-16 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases. Nat Commun, 15, 2024
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8VPN
| Phosphorylated human NCC in complex with indapamide | 分子名称: | 4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 3 | 著者 | Zhao, Y.X, Cao, E.H. | 登録日 | 2024-01-16 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases. Nat Commun, 15, 2024
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