6NP0
 
 | | Cryo-EM structure of 5HT3A receptor in presence of granisetron | | 分子名称: | 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Basak, S, Chakrapani, S. | | 登録日 | 2019-01-17 | | 公開日 | 2019-07-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Molecular mechanism of setron-mediated inhibition of full-length 5-HT3Areceptor.
Nat Commun, 10, 2019
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6W1M
 | | Cryo-EM structure of 5HT3A receptor in presence of Ondansetron | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | | 著者 | Basak, S, Chakrapani, S. | | 登録日 | 2020-03-04 | | 公開日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.
Elife, 9, 2020
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6W1Y
 | | Cryo-EM structure of 5HT3A receptor in presence of Palonosetron | | 分子名称: | (3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Basak, S, Chakrapani, S. | | 登録日 | 2020-03-04 | | 公開日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.
Elife, 9, 2020
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6W1J
 | | Cryo-EM structure of 5HT3A receptor in presence of Alosetron | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | | 著者 | Basak, S, Chakrapani, S. | | 登録日 | 2020-03-04 | | 公開日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.
Elife, 9, 2020
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