8AU3
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![BU of 8au3 by Molmil](/molmil-images/mine/8au3) | c-MET Y1234E,Y1235E mutant in complex with Tepotinib | 分子名称: | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, DI(HYDROXYETHYL)ETHER, Hepatocyte growth factor receptor, ... | 著者 | Graedler, U, Lammens, A. | 登録日 | 2022-08-25 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding. J.Biol.Chem., 299, 2023
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8AW1
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![BU of 8aw1 by Molmil](/molmil-images/mine/8aw1) | c-MET Y1235D mutant in complex with Tepotinib | 分子名称: | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, Hepatocyte growth factor receptor | 著者 | Graedler, U, Lammens, A. | 登録日 | 2022-08-29 | 公開日 | 2023-09-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding. J.Biol.Chem., 299, 2023
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8AU5
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![BU of 8au5 by Molmil](/molmil-images/mine/8au5) | c-MET F1200I mutant in complex with Tepotinib | 分子名称: | 1,2-ETHANEDIOL, 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, CHLORIDE ION, ... | 著者 | Graedler, U, Lammens, A. | 登録日 | 2022-08-25 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding. J.Biol.Chem., 299, 2023
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