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PDB: 5 件
3E32
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BU of 3e32 by Molmil
Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 2
分子名称: FARNESYL DIPHOSPHATE, N-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-1H-imidazole-4-sulfonamide, Protein farnesyltransferase subunit beta, ...
著者Hast, M.A, Beese, L.S.
登録日2008-08-06
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Chem.Biol., 16, 2009
3E34
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BU of 3e34 by Molmil
Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10
分子名称: 3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid, FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, ...
著者Hast, M.A, Beese, L.S.
登録日2008-08-06
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Chem.Biol., 16, 2009
3E33
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BU of 3e33 by Molmil
Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 7
分子名称: FARNESYL DIPHOSPHATE, N-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-2-methylbenzenesulfonamide, Protein farnesyltransferase subunit beta, ...
著者Hast, M.A, Beese, L.S.
登録日2008-08-06
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Chem.Biol., 16, 2009
3E37
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BU of 3e37 by Molmil
Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5
分子名称: Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ZINC ION, ...
著者Hast, M.A, Beese, L.S.
登録日2008-08-06
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Chem.Biol., 16, 2009
3E30
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BU of 3e30 by Molmil
Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4
分子名称: FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ...
著者Hast, M.A, Beese, L.S.
登録日2008-08-06
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Chem.Biol., 16, 2009

223166

件を2024-07-31に公開中

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