PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 3 件

SYK catalytic domain complexed with a potent and orally bioavailable benzisothiazole inhibitor
分子名称:	(5R)-5-[(1R)-1-{[6-(1-methyl-1H-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one, Tyrosine-protein kinase SYK
著者	Lee, C.C.
登録日	2015-07-30
公開日	2015-09-23
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.76 Å)
主引用文献	Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015

SYK catalytic domain complexed with naphthyridine inhibitor
分子名称:	CHLORIDE ION, GLYCEROL, N-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine, ...
著者	Thoma, G, Veenstra, S, Strang, R, Blanz, J, Vangrevelinghe, E, Berghausen, J, Lee, C.C, Zerwes, H.-G.
登録日	2015-07-29
公開日	2015-09-16
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015

SYK catalytic domain complexed with a potent orally bioavailable thiazole inhibitor
分子名称:	(4R)-4-[(1R)-1-{[6-(3,4-dimethoxyphenyl)[1,3]thiazolo[5,4-c]pyridin-4-yl]oxy}ethyl]pyrrolidin-2-one, Tyrosine-protein kinase SYK
著者	Lee, C.C.
登録日	2015-07-29
公開日	2015-09-23
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015