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PDB: 4 件

5AAD
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BU of 5aad by Molmil
Aurora A kinase bound to an imidazopyridine inhibitor (7a)
分子名称: 7-(1-benzyl-1H-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine, AURORA KINASE A, SULFATE ION
著者McIntyre, P.J, Kosmopoulou, M, Bayliss, R.
登録日2015-07-24
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bioorg.Med.Chem.Lett., 25, 2015
5AAF
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BU of 5aaf by Molmil
Aurora A kinase bound to an imidazopyridine inhibitor (14a)
分子名称: 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-N,N-dimethylbenzamide, AURORA KINASE A
著者McIntyre, P.J, Bayliss, R.
登録日2015-07-24
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bioorg.Med.Chem.Lett., 25, 2015
5AAG
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BU of 5aag by Molmil
Aurora A kinase bound to an imidazopyridine inhibitor (14b)
分子名称: AURORA KINASE A, [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone
著者McIntyre, P.J, Bayliss, R.
登録日2015-07-24
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bioorg.Med.Chem.Lett., 25, 2015
5AAE
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BU of 5aae by Molmil
Aurora A kinase bound to an imidazopyridine inhibitor (14d)
分子名称: 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-5-methylisoxazole, AURORA KINASE A
著者McIntyre, P.J, Bayliss, R.
登録日2015-07-24
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bioorg.Med.Chem.Lett., 25, 2015

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件を2024-06-12に公開中

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