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PDB: 10 件
8SBR
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BU of 8sbr by Molmil
E coli. CTP synthase in complex with CTP (sodium malonate + 20 mM MgCl2)
分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-04-04
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FV9
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BU of 8fv9 by Molmil
E coli. CTP synthase in complex with F-dCTP
分子名称: 2'-deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVB
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BU of 8fvb by Molmil
E coli. CTP synthase in complex with CTP
分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FV6
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BU of 8fv6 by Molmil
E coli. CTP synthase in complex with dF-dCTP
分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVE
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BU of 8fve by Molmil
E coli. CTP synthase in complex with CTP (potassium malonate + 100 mM MgCl2)
分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FV8
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BU of 8fv8 by Molmil
E coli. CTP synthase in complex with dF-dCTP + ADP
分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-DIPHOSPHATE, CTP synthase, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVC
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BU of 8fvc by Molmil
E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 5 mM MgCl2)
分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.281 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVA
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BU of 8fva by Molmil
E coli. CTP synthase in complex with F-araCTP
分子名称: 4-amino-1-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CTP synthase, MALONIC ACID, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVD
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BU of 8fvd by Molmil
E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 100 mM MgCl2)
分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MAGNESIUM ION, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FV7
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BU of 8fv7 by Molmil
E coli. CTP synthase in complex with dF-dCTP + ATP
分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023

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件を2024-10-16に公開中

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