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PDB: 224931 件

1Z5O
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Crystal structure of MTA/AdoHcy nucleosidase Asp197Asn mutant complexed with 5'-methylthioadenosine
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, MTA/SAH nucleosidase
著者Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L.
登録日2005-03-18
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
J.Mol.Biol., 352, 2005
1Z5P
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Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L.
登録日2005-03-18
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
J.Mol.Biol., 352, 2005
1Z5R
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Crystal Structure of Activated Porcine Pancreatic Carboxypeptidase B
分子名称: ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-03-18
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1Z5S
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Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2
分子名称: Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ...
著者Reverter, D, Lima, C.D.
登録日2005-03-19
公開日2005-06-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.
Nature, 435, 2005
1Z5T
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Crystal Structure of [d(CGCGAA(Z3dU)(Z3dU)CGCG)]2, Z3dU:5-(3-aminopropyl)-2'-deoxyuridine, in presence of thallium I.
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*(ZDU)P*(ZDU)P*CP*GP*CP*G)-3', SPERMINE, THALLIUM (I) ION
著者Moulaei, T, Maehigashi, T, Lountos, G.T, Komeda, S, Watkins, D, Stone, M.P, Marky, L.A, Li, J.S, Gold, B, Williams, L.D.
登録日2005-03-19
公開日2005-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of B-DNA with cations tethered in the major groove.
Biochemistry, 44, 2005
1Z5U
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Crystal structure of S. typhimurium AphA complexed with cyclic-AMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, AphA protein, MAGNESIUM ION
著者Makde, R.D, Kumar, V.
登録日2005-03-20
公開日2006-03-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Function of class-B bacterial non-specific acid phosphatase: functional role of invariant Lys154
To be Published
1Z5V
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Crystal structure of human gamma-tubulin bound to GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain
著者Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A.
登録日2005-03-20
公開日2005-05-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
1Z5W
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Crystal Structure of gamma-tubulin bound to GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain
著者Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A.
登録日2005-03-20
公開日2005-05-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
1Z5X
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hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
分子名称: 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, Ecdysone receptor ligand binding domain, PHOSPHATE ION, ...
著者Carmichael, J.A, Lawrence, M.C, Graham, L.D, Pilling, P.A, Epa, V.C, Noyce, L, Lovrecz, G, Winkler, D.A, Pawlak-Skrzecz, A.
登録日2005-03-21
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.
J.Biol.Chem., 280, 2005
1Z5Y
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Crystal Structure Of The Disulfide-Linked Complex Between The N-Terminal Domain Of The Electron Transfer Catalyst DsbD and The Cytochrome c Biogenesis Protein CcmG
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Thiol:disulfide interchange protein dsbD, ...
著者Stirnimann, C.U, Rozhkova, A, Grauschopf, U, Gruetter, M.G, Glockshuber, R, Capitani, G.
登録日2005-03-21
公開日2005-07-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis and Kinetics of DsbD-Dependent Cytochrome c Maturation
STRUCTURE, 13, 2005
1Z5Z
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Sulfolobus solfataricus SWI2/SNF2 ATPase C-terminal domain
分子名称: Helicase of the snf2/rad54 family
著者Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P.
登録日2005-03-21
公開日2005-05-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA
Cell(Cambridge,Mass.), 121, 2005
1Z60
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Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit
分子名称: TFIIH basal transcription factor complex p44 subunit, ZINC ION
著者Kellenberger, E, Dominguez, C, Fribourg, S, Wasielewski, E, Moras, D, Poterszman, A, Boelens, R, Kieffer, B.
登録日2005-03-21
公開日2005-04-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions.
J.Biol.Chem., 280, 2005
1Z62
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Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites
分子名称: ({[(3E)-2'-OXO-2',7'-DIHYDRO-2,3'-BIINDOL-3(7H)-YLIDENE]AMINO}OXY)ACETIC ACID, Glycogen phosphorylase, muscle form, ...
著者Kosmopoulou, M.N, Leonidas, D.D, Chrysina, E.D, Eisenbrand, G, Oikonomakos, N.G.
登録日2005-03-21
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Indirubin-3'-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites
LETT.DRUG DES.DISCOVERY, 2, 2005
1Z63
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Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
分子名称: 5'-D(*AP*AP*AP*AP*AP*A*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*AP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*TP*TP*TP*TP*TP*T)-3', Helicase of the snf2/rad54 family
著者Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P.
登録日2005-03-21
公開日2005-05-17
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA.
Cell(Cambridge,Mass.), 121, 2005
1Z64
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NMR Solution Structure of Pleurocidin in DPC Micelles
分子名称: Pleruocidin
著者Syvitski, R.T, Burton, I, Mattatall, N.R, Douglas, S.E, Jakeman, D.L.
登録日2005-03-21
公開日2005-04-12
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structural characterization of the antimicrobial peptide pleurocidin from winter flounder.
Biochemistry, 44, 2005
1Z65
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Mouse Doppel 1-30 peptide
分子名称: Prion-like protein doppel
著者Papadopoulos, E.
登録日2005-03-21
公開日2006-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Peptide Fragment 1-30, Derived from Unprocessed Mouse Doppel Protein, in DHPC Micelles
Biochemistry, 45, 2006
1Z66
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NMR solution structure of domain III of E-protein of tick-borne Langat flavivirus (no RDC restraints)
分子名称: Major envelope protein E
著者Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O.
登録日2005-03-21
公開日2006-03-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition.
Protein Sci., 15, 2006
1Z67
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Structure of Homeodomain-like Protein of Unknown Function S4005 from Shigella flexneri
分子名称: SODIUM ION, hypothetical protein S4005
著者Osipiuk, J, Maltseva, N, Dementieva, I, Clancy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-03-21
公開日2005-05-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif.
Proteins, 65, 2006
1Z68
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Crystal Structure Of Human Fibroblast Activation Protein alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Aertgeerts, K, Levin, I, Shi, L, Prasad, G.S, Zhang, Y, Kraus, M.L, Salakian, S, Snell, G.P, Sridhar, V, Wijnands, R, Tennant, M.G.
登録日2005-03-21
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
J.Biol.Chem., 280, 2005
1Z69
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Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CHLORIDE ION, COENZYME F420, ...
著者Aufhammer, S.W, Warkentin, E, Ermler, U, Hagemeier, C.H, Thauer, R.K, Shima, S.
登録日2005-03-22
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420: Architecture of the F420/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family
Protein Sci., 14, 2005
1Z6A
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Sulfolobus solfataricus SWI2/SNF2 ATPase core domain
分子名称: Helicase of the snf2/rad54 family, MERCURY (II) ION, PHOSPHATE ION
著者Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P.
登録日2005-03-22
公開日2005-05-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA
Cell(Cambridge,Mass.), 121, 2005
1Z6B
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Crystal structure of Plasmodium falciparum FabZ at 2.1 A
分子名称: CACODYLATE ION, CHLORIDE ION, SULFATE ION, ...
著者Kostrewa, D, Winkler, F.K, Folkers, G, Scapozza, L, Perozzo, R.
登録日2005-03-22
公開日2005-06-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum
PROTEIN SCI., 14, 2005
1Z6C
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Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S
分子名称: CALCIUM ION, Vitamin K-dependent protein S
著者Drakenberg, T, Ghasriani, H, Thulin, E, Thamlitz, A.M, Muranyi, A, Annila, A, Stenflo, J.
登録日2005-03-22
公開日2005-06-21
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3.
Biochemistry, 44, 2005
1Z6D
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Ribonuclease A- IMP complex
分子名称: INOSINIC ACID, Ribonuclease pancreatic
著者Hatzopoulos, G.N, Leonidas, D.D, Kardakaris, R, Kobe, J, Oikonomakos, N.G.
登録日2005-03-22
公開日2005-08-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献The binding of IMP to Ribonuclease A
Febs J., 272, 2005
1Z6E
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Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
分子名称: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation factor X
著者Alexander, R.S.
登録日2005-03-22
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.
J.Med.Chem., 48, 2005

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