4XHM
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5JY5
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![BU of 5jy5 by Molmil](/molmil-images/mine/5jy5) | Crystal structure of Thioredoxin 1 from Cryptococcus neoformans at 1.8 Angstroms resolution | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SULFATE ION, ... | Authors: | Bravo-Chaucanes, C.P, Abadio, A.K.R, Kioshima, E.S, Felipe, M.S.S, Barbosa, J.A.R.G. | Deposit date: | 2016-05-13 | Release date: | 2017-06-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Thioredoxin 1 from Cryptococcus neoformans at 1.8 Angstroms resolution To Be Published
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2VOC
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![BU of 2voc by Molmil](/molmil-images/mine/2voc) | THIOREDOXIN A ACTIVE SITE MUTANTS FORM MIXED DISULFIDE DIMERS THAT RESEMBLE ENZYME-SUBSTRATE REACTION INTERMEDIATE | Descriptor: | DI(HYDROXYETHYL)ETHER, THIOREDOXIN | Authors: | Kouwen, T.R.H.M, Andrell, J, Schrijver, R, Dubois, J.Y.F, Maher, M.J, Iwata, S, Carpenter, E.P, van Dijl, J.M. | Deposit date: | 2008-02-13 | Release date: | 2009-03-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Thioredoxin A active-site mutants form mixed disulfide dimers that resemble enzyme-substrate reaction intermediates. J. Mol. Biol., 379, 2008
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3F3R
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![BU of 3f3r by Molmil](/molmil-images/mine/3f3r) | Crystal structure of yeast Thioredoxin1-glutathione mixed disulfide complex | Descriptor: | GLUTATHIONE, SULFATE ION, Thioredoxin-1 | Authors: | Zhang, Y.R, Bao, R, Zhou, C.Z, Chen, Y.X. | Deposit date: | 2008-10-31 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system Biochim.Biophys.Acta, 1794, 2009
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1CQH
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![BU of 1cqh by Molmil](/molmil-images/mine/1cqh) | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | REF-1 PEPTIDE, THIOREDOXIN | Authors: | Clore, G.M, Qin, J, Gronenborn, A.M. | Deposit date: | 1996-04-02 | Release date: | 1996-08-01 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure, 4, 1996
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6MZA
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1CQG
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![BU of 1cqg by Molmil](/molmil-images/mine/1cqg) | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, 31 STRUCTURES | Descriptor: | REF-1 PEPTIDE, THIOREDOXIN | Authors: | Clore, G.M, Qin, J, Gronenborn, A.M. | Deposit date: | 1996-04-02 | Release date: | 1996-08-01 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure, 4, 1996
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8KGZ
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![BU of 8kgz by Molmil](/molmil-images/mine/8kgz) | Crystal structure of single-chain Fv antibody against antigen peptide from SARS-CoV2 S-spike protein | Descriptor: | Thioredoxin 1,scFv | Authors: | Ma, Q.Q, Zhang, B.L, Cheng, X.Y, Huang, Y.Q, Su, Z.D. | Deposit date: | 2023-08-20 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of sheep scFv antibody against an antigen peptide of SARS-CoV2 S-spike protein To Be Published
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1AIU
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![BU of 1aiu by Molmil](/molmil-images/mine/1aiu) | HUMAN THIOREDOXIN (D60N MUTANT, REDUCED FORM) | Descriptor: | THIOREDOXIN | Authors: | Andersen, J.F, Gasdaska, J.R, Sanders, D.A.R, Weichsel, A, Powis, G, Montfort, W.R. | Deposit date: | 1997-04-25 | Release date: | 1997-07-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant. Biochemistry, 36, 1997
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6NUP
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1AUC
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![BU of 1auc by Molmil](/molmil-images/mine/1auc) | HUMAN THIOREDOXIN (OXIDIZED WITH DIAMIDE) | Descriptor: | THIOREDOXIN | Authors: | Anderson, J.F, Sanders, D.A.R, Gasdaska, J, Weichsel, A, Powis, G, Montfort, W.R. | Deposit date: | 1997-08-22 | Release date: | 1998-02-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant. Biochemistry, 36, 1997
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8QPD
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![BU of 8qpd by Molmil](/molmil-images/mine/8qpd) | Structure of thioredoxin m from pea | Descriptor: | Thioredoxin M-type, chloroplastic | Authors: | Neira, J.L, Camara Artigas, A. | Deposit date: | 2023-10-01 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure, dynamics and binding of thioredoxin m from Pisum sativum. Int.J.Biol.Macromol., 262, 2024
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7XAO
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![BU of 7xao by Molmil](/molmil-images/mine/7xao) | Crystal structure of thioredoxin 1 | Descriptor: | Thioredoxin | Authors: | Chang, Y.J, Park, H.H. | Deposit date: | 2022-03-18 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structure of Acinetobacter baumannii thioredoxin 1. Biochem.Biophys.Res.Commun., 608, 2022
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3KD0
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7OOL
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![BU of 7ool by Molmil](/molmil-images/mine/7ool) | Crystal structure of a Candidatus photodesmus katoptron thioredoxin chimera containing an ancestral loop | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Gavira, J.A, Ibarra-Molero, B, Gamiz-Arco, G, Risso, V, Sanchez-Ruiz, J.M. | Deposit date: | 2021-05-28 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression. J.Mol.Biol., 433, 2021
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2J23
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![BU of 2j23 by Molmil](/molmil-images/mine/2j23) | Cross-reactivity and crystal structure of Malassezia sympodialis Thioredoxin (Mala s 13), a member of a new pan-allergen family | Descriptor: | THIOREDOXIN | Authors: | Limacher, A, Glaser, A.G, Meier, C, Scapozza, L, Crameri, R. | Deposit date: | 2006-08-16 | Release date: | 2006-11-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family. J Immunol., 178, 2007
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2IIY
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2IFQ
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6X0B
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3M9J
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3M9K
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![BU of 3m9k by Molmil](/molmil-images/mine/3m9k) | Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, SULFATE ION, Thioredoxin | Authors: | Weichsel, A, Montfort, W.R. | Deposit date: | 2010-03-22 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site. Protein Sci., 19, 2010
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8GDY
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![BU of 8gdy by Molmil](/molmil-images/mine/8gdy) | Crystal structure of the human PDI first domain with 9 mutations | Descriptor: | 1,2-ETHANEDIOL, Protein disulfide-isomerase, THIOCYANATE ION | Authors: | Forouhar, F, Banayan, N.E, Loughlin, B.L, Singh, S, Wong, V, Hunt, H.S, Handelman, S.K, Price, N, Hunt, J.F. | Deposit date: | 2023-03-06 | Release date: | 2024-01-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci., 33, 2024
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6CKP
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5VO7
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6ESX
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![BU of 6esx by Molmil](/molmil-images/mine/6esx) | Caulobacter crescentus Trx1 | Descriptor: | Thioredoxin 1 | Authors: | Van Molle, I, Wahni, K, Goemans, C.V, Beaufay, F, Collet, J.F, Messens, J. | Deposit date: | 2017-10-24 | Release date: | 2018-01-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | An essential thioredoxin is involved in the control of the cell cycle in the bacterium J. Biol. Chem., 293, 2018
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