8W0Y
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8V6M
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![BU of 8v6m by Molmil](/molmil-images/mine/8v6m) | Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6L
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![BU of 8v6l by Molmil](/molmil-images/mine/8v6l) | Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6K
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![BU of 8v6k by Molmil](/molmil-images/mine/8v6k) | Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6O
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![BU of 8v6o by Molmil](/molmil-images/mine/8v6o) | Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, SODIUM ION, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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7KFB
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![BU of 7kfb by Molmil](/molmil-images/mine/7kfb) | Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-442 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-442 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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7KEX
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7KEW
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![BU of 7kew by Molmil](/molmil-images/mine/7kew) | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BDBV-43 Fab heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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7KF9
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7KFG
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![BU of 7kfg by Molmil](/molmil-images/mine/7kfg) | Antibody Fab BDBV-289 | Descriptor: | Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER | Authors: | Murin, C.D, Bruhn, J.F, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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7KFE
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![BU of 7kfe by Molmil](/molmil-images/mine/7kfe) | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody BDBV-329 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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3E2K
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![BU of 3e2k by Molmil](/molmil-images/mine/3e2k) | Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) | Descriptor: | Beta-lactamase inhibitory protein, Carbapenemase | Authors: | Hanes, M.S, Jude, K.M, Berger, J.M, Bonomo, R.A, Handel, T.M. | Deposit date: | 2008-08-05 | Release date: | 2009-08-04 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein Biochemistry, 48, 2009
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4QBB
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![BU of 4qbb by Molmil](/molmil-images/mine/4qbb) | Structure of the foot-and-mouth disease virus leader proteinase in complex with inhibitor (N~2~-[(3S)-4-({(2R)-1-[(4-CARBAMIMIDAMIDOBUTYL)AMINO]-4-METHYL-1-OXOPENTAN-2-YL}AMINO)-3-HYDROXY-4-OXOBUTANOYL]-L-ARGINYL-L-PROLINAMIDE) | Descriptor: | Leader protease, N~2~-[(3S)-4-({(2R)-1-[(4-carbamimidamidobutyl)amino]-4-methyl-1-oxopentan-2-yl}amino)-3-hydroxy-4-oxobutanoyl]-L-arginyl-L-prolinamide, PHOSPHATE ION, ... | Authors: | Grishkovskaya, I, Steinberger, J, Cencic, R, Juliano, M.A, Juliano, L, Skern, T. | Deposit date: | 2014-05-07 | Release date: | 2014-11-05 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage. Virology, 468-470C, 2014
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3G7W
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![BU of 3g7w by Molmil](/molmil-images/mine/3g7w) | Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | Authors: | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2009-02-11 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
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3G7V
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![BU of 3g7v by Molmil](/molmil-images/mine/3g7v) | Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | Authors: | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2009-02-10 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
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3GC6
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![BU of 3gc6 by Molmil](/molmil-images/mine/3gc6) | Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION | Authors: | Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N, Kellenberger, E, Schuber, F. | Deposit date: | 2009-02-21 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One, 7, 2012
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3GHH
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![BU of 3ghh by Molmil](/molmil-images/mine/3ghh) | Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION, ... | Authors: | Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N.J, Kellenberger, E, Schuber, F. | Deposit date: | 2009-03-03 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One, 7, 2012
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3GH3
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![BU of 3gh3 by Molmil](/molmil-images/mine/3gh3) | Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, Ecto-NAD+ glycohydrolase (CD38 molecule), ... | Authors: | Egea, P.F, Muller-Steffner, H, Stroud, R.M, Kellenberger, E, Oppenheimer, N, Schuber, F. | Deposit date: | 2009-03-02 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One, 7, 2012
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7KEJ
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![BU of 7kej by Molmil](/molmil-images/mine/7kej) | BDBV-289 bound to EBOV GPdMuc Makona | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain (HC) BDBV-289, Antibody Fab light chain (LC) BDBV-289, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-11 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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7KFH
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![BU of 7kfh by Molmil](/molmil-images/mine/7kfh) | Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-437 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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4U1E
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![BU of 4u1e by Molmil](/molmil-images/mine/4u1e) | Crystal structure of the eIF3b-CTD/eIF3i/eIF3g-NTD translation initiation complex | Descriptor: | Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit I | Authors: | Zhang, S, Erzberger, J.P, Schaefer, T, Ban, N. | Deposit date: | 2014-07-15 | Release date: | 2014-09-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex. Cell, 158, 2014
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4U1F
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![BU of 4u1f by Molmil](/molmil-images/mine/4u1f) | |
3E2L
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![BU of 3e2l by Molmil](/molmil-images/mine/3e2l) | Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) | Descriptor: | Beta-lactamase inhibitory protein, Carbapenemase | Authors: | Hanes, M.S, Jude, K.M, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | Deposit date: | 2008-08-05 | Release date: | 2009-08-04 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein Biochemistry, 48, 2009
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3HJT
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![BU of 3hjt by Molmil](/molmil-images/mine/3hjt) | |
7PL9
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![BU of 7pl9 by Molmil](/molmil-images/mine/7pl9) | |