7P69
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![BU of 7p69 by Molmil](/molmil-images/mine/7p69) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P62
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![BU of 7p62 by Molmil](/molmil-images/mine/7p62) | Complex I from E. coli, DDM-purified, Apo, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7L
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![BU of 7p7l by Molmil](/molmil-images/mine/7p7l) | Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P61
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![BU of 7p61 by Molmil](/molmil-images/mine/7p61) | Complex I from E. coli, DDM-purified, with NADH, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P64
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![BU of 7p64 by Molmil](/molmil-images/mine/7p64) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7C
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![BU of 7p7c by Molmil](/molmil-images/mine/7p7c) | Complex I from E. coli, DDM/LMNG-purified, Apo, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7E
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![BU of 7p7e by Molmil](/molmil-images/mine/7p7e) | Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7J
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![BU of 7p7j by Molmil](/molmil-images/mine/7p7j) | Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7M
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![BU of 7p7m by Molmil](/molmil-images/mine/7p7m) | Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7K
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![BU of 7p7k by Molmil](/molmil-images/mine/7p7k) | Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7PSA
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![BU of 7psa by Molmil](/molmil-images/mine/7psa) | The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | Descriptor: | (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Grba, D, Hirst, J. | Deposit date: | 2021-09-22 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I. J.Biol.Chem., 298, 2022
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7Q5Y
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![BU of 7q5y by Molmil](/molmil-images/mine/7q5y) | |
7QSD
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![BU of 7qsd by Molmil](/molmil-images/mine/7qsd) | Bovine complex I in the active state at 3.1 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-01-13 | Release date: | 2022-03-02 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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4TTT
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![BU of 4ttt by Molmil](/molmil-images/mine/4ttt) | |
4UD2
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![BU of 4ud2 by Molmil](/molmil-images/mine/4ud2) | Structure of anaerobically purified D. fructosovorans NiFe- hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | Deposit date: | 2014-12-05 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | [Nife]-Hydrogenases Revisited: Nickel-Carboxamido Bond Formation in a Variant with Accrued O2-Tolerance and a Tentative Re-Interpretation of Ni-Si States. Metallomics, 7, 2015
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4UE3
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![BU of 4ue3 by Molmil](/molmil-images/mine/4ue3) | The Mechanism of Hydrogen Activation by NiFe-hydrogenases and the Importance of the active site Arginine | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Evans, R.M, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | Deposit date: | 2014-12-15 | Release date: | 2014-12-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mechanism of Hydrogen Activation by [Nife] Hydrogenases. Nat.Chem.Biol., 12, 2016
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4UCX
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![BU of 4ucx by Molmil](/molmil-images/mine/4ucx) | Structure of the T18G small subunit mutant of D. fructosovorans NiFe- hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Abou-Hamdan, A, Ceccaldi, P, Lebrette, H, Guttierez-Sanz, O, Richaud, P, Cournac, L, Guigliarelli, B, deLacey, A.L, Leger, C, Volbeda, A, Burlat, B, Dementin, S. | Deposit date: | 2014-12-05 | Release date: | 2015-02-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A threonine stabilizes the NiC and NiR catalytic intermediates of [NiFe]-hydrogenase. J. Biol. Chem., 290, 2015
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4UPV
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![BU of 4upv by Molmil](/molmil-images/mine/4upv) | Low X-ray dose structure of a Ni-A Ni-Sox mixture of the D. fructosovorans NiFe-hydrogenase L122A mutant | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Volbeda, A, Martin, L, Barbier, E, Gutierrez-Sanz, O, DeLacey, A.L, Liebgott, P.P, Dementin, S, Rousset, M, Fontecilla-Camps, J.C. | Deposit date: | 2014-06-18 | Release date: | 2014-10-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states. J. Biol. Inorg. Chem., 20, 2015
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4UD6
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![BU of 4ud6 by Molmil](/molmil-images/mine/4ud6) | Structure of methylviologen-treated anaerobically purified D. fructosovorans NiFe-hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | Deposit date: | 2014-12-08 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | [NiFe]-hydrogenases revisited: nickel-carboxamido bond formation in a variant with accrued O2-tolerance and a tentative re-interpretation of Ni-SI states. Metallomics, 7, 2015
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4UEQ
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![BU of 4ueq by Molmil](/molmil-images/mine/4ueq) | Structure of the V74C large subunit mutant of D. fructosovorans NiFe- hydrogenase | Descriptor: | CALCIUM ION, CARBONATE ION, CARBONMONOXIDE-(DICYANO) IRON, ... | Authors: | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | Deposit date: | 2014-12-18 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | [NiFe]-hydrogenases revisited: nickel-carboxamido bond formation in a variant with accrued O2-tolerance and a tentative re-interpretation of Ni-SI states. Metallomics, 7, 2015
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4UCQ
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![BU of 4ucq by Molmil](/molmil-images/mine/4ucq) | Structure of the T18D small subunit mutant of D. fructosovorans NiFe- hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Abou-Hamdan, A, Ceccaldi, P, Lebrette, H, Guttierez-Sanz, O, Richaud, P, Cournac, L, Guigliarelli, B, deLacey, A.L, Leger, C, Volbeda, A, Burlat, B, Dementin, S. | Deposit date: | 2014-12-04 | Release date: | 2015-02-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A threonine stabilizes the NiC and NiR catalytic intermediates of [NiFe]-hydrogenase. J. Biol. Chem., 290, 2015
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4UE6
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![BU of 4ue6 by Molmil](/molmil-images/mine/4ue6) | Structure of methylene blue-treated anaerobically purified D. fructosovorans NiFe-hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | Deposit date: | 2014-12-16 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | [Nife]-Hydrogenases Revisited: Nickel-Carboxamido Bond Formation in a Variant with Accrued O2-Tolerance and a Tentative Re-Interpretation of Ni-Si States. Metallomics, 7, 2015
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4UEW
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![BU of 4uew by Molmil](/molmil-images/mine/4uew) | Structure of H2-treated anaerobically purified D. fructosovorans NiFe- hydrogenase | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | Deposit date: | 2014-12-20 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | [NiFe]-hydrogenases revisited: nickel-carboxamido bond formation in a variant with accrued O2-tolerance and a tentative re-interpretation of Ni-SI states. Metallomics, 7, 2015
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4UPE
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![BU of 4upe by Molmil](/molmil-images/mine/4upe) | Structure of the unready Ni-A state of the S499C mutant of D. fructosovorans NiFe-hydrogenase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONMONOXIDE-(DICYANO) IRON, ... | Authors: | Volbeda, A, Martin, L, Barbier, E, Gutierrez-Sanz, O, DeLacey, A.L, Liebgott, P.P, Dementin, S, Rousset, M, Fontecilla-Camps, J.C. | Deposit date: | 2014-06-16 | Release date: | 2014-10-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states. J. Biol. Inorg. Chem., 20, 2015
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4U9H
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![BU of 4u9h by Molmil](/molmil-images/mine/4u9h) | Ultra High Resolution Structure Of The Ni-R State Of [Nife]Hydrogenase From Desulufovibrio Vulgaris Miyazaki F | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE3-S4 CLUSTER, ... | Authors: | Ogata, H, Nishikawa, K, Lubitz, W. | Deposit date: | 2014-08-06 | Release date: | 2015-01-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | Hydrogens detected by subatomic resolution protein crystallography in a [NiFe] hydrogenase. Nature, 520, 2015
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