3MMB
 
 | | Dissimilatory sulfite reductase in complex with the endproduct sulfide | | Descriptor: | HYDROSULFURIC ACID, IRON/SULFUR CLUSTER, SIROHEME, ... | | Authors: | Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2010-04-19 | | Release date: | 2010-07-21 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus.
Biochemistry, 49, 2010
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2OHJ
 | | Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, inactive oxidized state | | Descriptor: | CHLORIDE ION, FE (III) ION, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Seedorf, H, Warkentin, E, Ermler, U. | | Deposit date: | 2007-01-10 | | Release date: | 2007-05-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O.
Febs J., 274, 2007
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3OYZ
 | | Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | | Descriptor: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | | Deposit date: | 2010-09-24 | | Release date: | 2011-06-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Bmc Struct.Biol., 11, 2011
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2OHI
 | | Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, reduced state | | Descriptor: | CHLORIDE ION, FE (III) ION, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Seedorf, H, Warkentin, E, Ermler, U. | | Deposit date: | 2007-01-10 | | Release date: | 2007-05-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O.
Febs J., 274, 2007
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3MM7
 | | Dissimilatory sulfite reductase carbon monoxide complex | | Descriptor: | CARBON MONOXIDE, IRON/SULFUR CLUSTER, SIROHEME, ... | | Authors: | Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2010-04-19 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus.
Biochemistry, 49, 2010
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8QQB
 | | Crystal structure of protein kinase CK2 catalytic subunit in complex with a Dibromo Dihydro Dibenzofuranone derivative | | Descriptor: | (4~{Z})-7,9-bis(bromanyl)-8-oxidanyl-4-(phenylazanylmethylidene)-1,2-dihydrodibenzofuran-3-one, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... | | Authors: | Werner, C, Niefind, K, Jose, J. | | Deposit date: | 2023-10-04 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Discovery of 7,9-Dibromo Dihydrodibenzofuran as Potent and Highly Selective CK2 inhibitor: Synthesis, Biological Evaluation and Structural Studies on E-/Z isomers
To be published
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3MMC
 | | Structure of the dissimilatory sulfite reductase from Archaeoglobus fulgidus | | Descriptor: | GLYCEROL, IRON/SULFUR CLUSTER, SIROHEME, ... | | Authors: | Schiffer, A, Parey, K, Warkentin, E, Diederichs, K, Huber, H, Stetter, K.O, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2010-04-19 | | Release date: | 2010-05-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus.
J.Mol.Biol., 379, 2008
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3M97
 | | Structure of the soluble domain of cytochrome c552 with its flexible linker segment from Paracoccus denitrificans | | Descriptor: | Cytochrome c-552, HEME C, ZINC ION | | Authors: | Rajendran, C, Ermler, U, Ludwig, B, Michel, H. | | Deposit date: | 2010-03-20 | | Release date: | 2010-07-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.332 Å) | | Cite: | Structure at 1.5 A resolution of cytochrome c(552) with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans.
Acta Crystallogr.,Sect.D, 66, 2010
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3MM8
 | | Dissimilatory sulfite reductase nitrate complex | | Descriptor: | IRON/SULFUR CLUSTER, NITRATE ION, SIROHEME, ... | | Authors: | Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2010-04-19 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus.
Biochemistry, 49, 2010
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2OHH
 | | Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, active oxidized state | | Descriptor: | FE (III) ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | | Authors: | Seedorf, H, Warkentin, E, Ermler, U. | | Deposit date: | 2007-01-10 | | Release date: | 2007-05-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O.
Febs J., 274, 2007
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3MMA
 | | Dissimilatory sulfite reductase phosphate complex | | Descriptor: | IRON/SULFUR CLUSTER, PHOSPHATE ION, SIROHEME, ... | | Authors: | Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2010-04-19 | | Release date: | 2010-07-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus.
Biochemistry, 49, 2010
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3OZW
 | | The Crystal Structure of flavohemoglobin from R. eutrophus in complex with ketoconazole | | Descriptor: | 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | El Hammi, E, Warkentin, E, Demmer, U, Ermler, U, Baciou, L. | | Deposit date: | 2010-09-27 | | Release date: | 2011-03-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds.
Biochemistry, 50, 2011
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2OGX
 | | The crystal structure of the molybdenum storage protein from Azotobacter vinelandii loaded with polyoxotungstates (WSto) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Molybdenum storage protein subunit alpha, ... | | Authors: | Schemberg, J, Warkentin, E, Ermler, U. | | Deposit date: | 2007-01-09 | | Release date: | 2007-04-24 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Towards Biological Supramolecular Chemistry: A Variety of Pocket-Templated, Individual Metal Oxide Cluster Nucleations in the Cavity of a Mo/W-Storage Protein.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2PGN
 | | The crystal structure of FAD and ThDP-dependent Cyclohexane-1,2-dione Hydrolase in Complex with Cyclohexane-1,2-dione | | Descriptor: | CYCLOHEXANE-1,2-DIONE, Cyclohexane-1,2-dione Hydrolase (Cdh), FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Fraas, S, Warkentin, E, Ermler, U. | | Deposit date: | 2007-04-10 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The crystal structure of FAD and ThDP-dependent Cyclohexane-1,2-dione Hydrolase in Complex with Cyclohexane-1,2-dione
To be Published
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3OZU
 | | The Crystal Structure of flavohemoglobin from R. eutrophus in complex with miconazole | | Descriptor: | 1-[(2R)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, FLAVIN-ADENINE DINUCLEOTIDE, Flavohemoprotein, ... | | Authors: | El Hammi, E, Warkentin, E, Demmer, U, Ermler, U, Baciou, L. | | Deposit date: | 2010-09-27 | | Release date: | 2011-03-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds.
Biochemistry, 50, 2011
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3OZV
 | | The Crystal Structure of flavohemoglobin from R. eutrophus in complex with econazole | | Descriptor: | 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | El Hammi, E, Warkentin, E, Demmer, U, Ermler, U, Baciou, L. | | Deposit date: | 2010-09-27 | | Release date: | 2011-03-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds.
Biochemistry, 50, 2011
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3PER
 | | Crystal Structure of BoxB with phosphate bound to the diiron center | | Descriptor: | Benzoyl-CoA oxygenase component B, FE (III) ION, GLYCEROL, ... | | Authors: | Weinert, T, Rather, L.J, Fuchs, G, Ermler, U. | | Deposit date: | 2010-10-27 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB.
J.Biol.Chem., 286, 2011
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3PF7
 | | Crystal structure of BoxB with malonate bound to the diiron center | | Descriptor: | Benzoyl-CoA oxygenase component B, CHLORIDE ION, FE (III) ION, ... | | Authors: | Weinert, T, Rather, L.J, Fuchs, G, Ermler, U. | | Deposit date: | 2010-10-28 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB.
J.Biol.Chem., 286, 2011
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3PUG
 | | Haloferax volcanii Malate Synthase Native at 3mM Glyoxylate | | Descriptor: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | | Authors: | Howard, B.R, Bracken, C.D, Neighbor, A.M, Thomas, G.C, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | | Deposit date: | 2010-12-04 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Bmc Struct.Biol., 11, 2011
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3PM5
 | | Crystal Structure of BoxB in mixed valent state with bound benzoyl-CoA | | Descriptor: | Benzoyl-CoA oxygenase component B, CHLORIDE ION, FE (III) ION, ... | | Authors: | Weinert, T, Rather, L, Fuchs, G, Ermler, U. | | Deposit date: | 2010-11-16 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB.
J.Biol.Chem., 286, 2011
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2PGO
 | | The crystal structure of FAD and ThDP dependent Cyclohexane-1,2-dione Hydrolase (Cdh) from Azoarcus sp. strain 22Lin | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cyclohexane-1,2-dione Hydrolase (Cdh), ... | | Authors: | Steinbach, A.K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | | Deposit date: | 2007-04-10 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | The crystal structure of FAD and ThDP dependent Cyclohexane-1,2-dione Hydrolase (Cdh) from Azoarcus sp. strain 22Lin
To be Published
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3Q1G
 | | Crystal Structure of BoxB crystallized with PEG | | Descriptor: | Benzoyl-CoA oxygenase component B, CHLORIDE ION, FE (III) ION, ... | | Authors: | Weinert, T, Rather, L, Fuchs, G, Ermler, U. | | Deposit date: | 2010-12-17 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB.
J.Biol.Chem., 286, 2011
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9FYD
 | | tubulin - cryptophycin-uD[Dab] complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Dessin, C, Schachtsiek, T, Voss, J, Abel, A.-C, Neumann, B, Stammler, H.-G, Prota, A.E, Sewald, N. | | Deposit date: | 2024-07-03 | | Release date: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Highly Cytotoxic Cryptophycin Derivatives with Modification in Unit D for Conjugation.
Angew.Chem.Int.Ed.Engl., 2024
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6CQ5
 | | TBK1 in Complex with Sulfone Analog of Amlexanox | | Descriptor: | 2-amino-7-(1,1-dioxo-1lambda~6~-thian-4-yl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, Serine/threonine-protein kinase TBK1 | | Authors: | Beyett, T.S, Tesmer, J.J.G. | | Deposit date: | 2018-03-14 | | Release date: | 2018-12-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.354 Å) | | Cite: | Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK epsilon for the treatment of obesity.
Bioorg. Med. Chem., 26, 2018
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6CQ4
 | | TBK1 in Complex with Cyclohexyl Analog of Amlexanox | | Descriptor: | 2-amino-7-(4,4-difluorocyclohexyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, Serine/threonine-protein kinase TBK1 | | Authors: | Beyett, T.S, Tesmer, J.J.G. | | Deposit date: | 2018-03-14 | | Release date: | 2018-12-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK epsilon for the treatment of obesity.
Bioorg. Med. Chem., 26, 2018
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