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2LM8
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BU of 2lm8 by Molmil
Structure, Activity and Interactions of the Cysteine Deleted Analog of Tachyplesin-1 with Lipopolysaccharide Micelles
Descriptor: CDT-LPS
Authors:Joshi, M, Bhattacharjya, S, Saravanan, R.
Deposit date:2011-11-25
Release date:2012-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, activity and interactions of the cysteine deleted analog of tachyplesin-1 with lipopolysaccharide micelle: Mechanistic insights into outer-membrane permeabilization and endotoxin neutralization.
Biochim.Biophys.Acta, 1818, 2012
4RQX
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BU of 4rqx by Molmil
Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA
Descriptor: 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4
Authors:Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
Deposit date:2014-11-05
Release date:2015-04-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
2MW7
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BU of 2mw7 by Molmil
Solution NMR structure of a novel cysteine framework containing Conus peptide Mo3964
Descriptor: Mo3964
Authors:Sarma, S.P, Kancherla, A.
Deposit date:2014-10-29
Release date:2015-09-23
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:A Disulfide Stabilized beta-Sandwich Defines the Structure of a New Cysteine Framework M-Superfamily Conotoxin
Acs Chem.Biol., 10, 2015
4RQR
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BU of 4rqr by Molmil
Crystal Structure of Human Glutaredoxin with MESNA
Descriptor: 1-THIOETHANESULFONIC ACID, Glutaredoxin-1
Authors:Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
Deposit date:2014-11-04
Release date:2015-04-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
3PEE
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BU of 3pee by Molmil
Structure of the C. difficile TcdB cysteine protease domain
Descriptor: CALCIUM ION, INOSITOL HEXAKISPHOSPHATE, Toxin B
Authors:Lupardus, P.J, Garcia, K.C.
Deposit date:2010-10-26
Release date:2011-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins.
Nat.Struct.Mol.Biol., 18, 2011
8D8S
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BU of 8d8s by Molmil
SufS from Staphylococcus aureus
Descriptor: 1,2-ETHANEDIOL, Cysteine desulfurase
Authors:Morrison, C.N, Boncella, A.E, Lunin, V.
Deposit date:2022-06-08
Release date:2022-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.388 Å)
Cite:Structural and Biochemical Characterization of Staphylococcus aureus Cysteine Desulfurase Complex SufSU.
Acs Omega, 7, 2022
3L76
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BU of 3l76 by Molmil
Crystal Structure of Aspartate Kinase from Synechocystis
Descriptor: Aspartokinase, LYSINE, SULFATE ION, ...
Authors:Robin, A, Cobessi, D, Curien, G, Robert-Genthon, M, Ferrer, J.-L, Dumas, R.
Deposit date:2009-12-28
Release date:2010-06-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
J.Mol.Biol., 399, 2010
3SBC
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BU of 3sbc by Molmil
Crystal structure of Saccharomyces cerevisiae TSA1C47S mutant protein
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Peroxiredoxin TSA1
Authors:Tairum Jr, C.A, Horta, B.B, Netto, L.E.S, Oliveira, M.A.
Deposit date:2011-06-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Disulfide biochemistry in 2-cys peroxiredoxin: requirement of Glu50 and Arg146 for the reduction of yeast Tsa1 by thioredoxin.
J.Mol.Biol., 424, 2012
7N2T
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BU of 7n2t by Molmil
O-acetylserine sulfhydrylase from Citrullus vulgaris in the internal aldimine state, with citrate bound
Descriptor: CITRIC ACID, Cysteine synthase, PENTAETHYLENE GLYCOL, ...
Authors:Smith, J.L, Buller, A.R, Bingman, C.A.
Deposit date:2021-05-29
Release date:2022-07-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Investigation of beta-Substitution Activity of O-Acetylserine Sulfhydrolase from Citrullus vulgaris.
Chembiochem, 23, 2022
4JH8
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BU of 4jh8 by Molmil
Crystal Structure of FosB from Bacillus cereus with Zinc and L-Cysteine-Fosfomycin Ternary Complex
Descriptor: CYSTEINE, FOSFOMYCIN, GLYCEROL, ...
Authors:Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
Deposit date:2013-03-04
Release date:2013-10-02
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
4NB1
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BU of 4nb1 by Molmil
Crystal Structure of FosB from Staphylococcus aureus at 1.80 Angstrom Resolution with L-Cysteine-Cys9 Disulfide
Descriptor: CYSTEINE, Metallothiol transferase FosB, SULFATE ION
Authors:Cook, P.D, Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Armstrong, R.N.
Deposit date:2013-10-22
Release date:2014-02-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus.
Biochemistry, 53, 2014
4TNW
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BU of 4tnw by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ...
Authors:Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E.
Deposit date:2014-06-05
Release date:2014-08-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
4TNV
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BU of 4tnv by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ...
Authors:Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E.
Deposit date:2014-06-05
Release date:2014-08-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
4NB0
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BU of 4nb0 by Molmil
Crystal Structure of FosB from Staphylococcus aureus with BS-Cys9 disulfide at 1.62 Angstrom Resolution
Descriptor: CYSTEINE, GLYCEROL, Metallothiol transferase FosB, ...
Authors:Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N.
Deposit date:2013-10-22
Release date:2014-02-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus.
Biochemistry, 53, 2014
6Z0M
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BU of 6z0m by Molmil
Het-Ncap - De novo designed three-helix heterodimer with Cysteine at the Ncap position of the alpha-helix
Descriptor: Cys-Ncap strand, Positive Strand, SULFATE ION, ...
Authors:McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V.
Deposit date:2020-05-09
Release date:2021-03-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site.
J.Am.Chem.Soc., 143, 2021
8ZTS
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BU of 8zts by Molmil
Cryo-EM structure of the ZAC zinc-activated channel in amphipol
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ZAC
Authors:Jin, F, Hattori, M.
Deposit date:2024-06-07
Release date:2024-11-27
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the zinc-activated channel (ZAC) in the Cys-loop receptor superfamily.
Proc.Natl.Acad.Sci.USA, 121, 2024
2DU7
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BU of 2du7 by Molmil
Crystal structure of Methanococcus jannacshii O-phosphoseryl-tRNA synthetase
Descriptor: O-phosphoseryl-tRNA synthetase
Authors:Fukunaga, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-07-20
Release date:2007-03-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.
Nat.Struct.Mol.Biol., 14, 2007
2DU5
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BU of 2du5 by Molmil
Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase E418N/E420N mutant complexed with tRNAOpal and O-phosphoserine ("opal complex")
Descriptor: O-phosphoseryl-tRNA synthetase, PHOSPHOSERINE, tRNA
Authors:Fukunaga, R.
Deposit date:2006-07-20
Release date:2007-03-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.
Nat.Struct.Mol.Biol., 14, 2007
2DU6
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BU of 2du6 by Molmil
Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase E418N/E420N mutant complexed with tRNAAmber and O-phosphoserine ("amber complex")
Descriptor: O-phosphoseryl-tRNA synthetase, PHOSPHOSERINE, tRNA
Authors:Fukunaga, R.
Deposit date:2006-07-20
Release date:2007-03-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.
Nat.Struct.Mol.Biol., 14, 2007
8OVH
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BU of 8ovh by Molmil
Crystal structure of O-acetyl-L-homoserine sulfhydrolase from Saccharomyces cerevisiae in complex with Pyridoxal-5'-phosphate
Descriptor: DI(HYDROXYETHYL)ETHER, Homocysteine/cysteine synthase, PYRIDOXAL-5'-PHOSPHATE
Authors:Saleem-Batcha, R, Andexer, J.N, Mohr, M.
Deposit date:2023-04-26
Release date:2023-06-21
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.171 Å)
Cite:Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade.
Chemistry, 29, 2023
3ZTL
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BU of 3ztl by Molmil
Crystal structure of decameric form of Peroxiredoxin I from Schistosoma mansoni
Descriptor: THIOREDOXIN PEROXIDASE
Authors:Saccoccia, F, Angelucci, F, Bellelli, A, Boumis, G, Brunori, M, Miele, A.E.
Deposit date:2011-07-11
Release date:2012-03-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin.
Structure, 20, 2012
3Q1X
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BU of 3q1x by Molmil
Crystal structure of Entamoeba histolytica serine acetyltransferase 1 in complex with L-serine
Descriptor: SERINE, SULFATE ION, Serine acetyltransferase
Authors:Kumar, S, Gourinath, S.
Deposit date:2010-12-18
Release date:2011-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural and biochemical studies of serine acetyltransferase reveal why the parasite Entamoeba histolytica cannot form cysteine synthase complex
J.Biol.Chem., 2011
3P1B
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BU of 3p1b by Molmil
Crystal structure of the native serine acetyltransferase 1 from Entamoeba histolytica
Descriptor: SULFATE ION, Serine acetyltransferase
Authors:Kumar, S, Gourinath, S.
Deposit date:2010-09-30
Release date:2011-02-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural and biochemical studies of serine acetyltransferase reveal why the parasite Entamoeba histolytica cannot form a cysteine synthase complex
J.Biol.Chem., 286, 2011
4YEU
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BU of 4yeu by Molmil
ELIC-GLIC chimera in the resting conformation
Descriptor: Cys-loop ligand-gated ion channel,Proton-gated ion channel
Authors:Schmandt, N, Vivien, Y, Lodowski, D, Chakrapani, S.
Deposit date:2015-02-24
Release date:2015-09-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:An ELIC-GLIC Chimera Reveals Distinct Pathways of Activation in the Cys-loop receptors
To Be Published
3ZVJ
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BU of 3zvj by Molmil
Crystal structure of high molecular weight (HMW) form of Peroxiredoxin I from Schistosoma mansoni
Descriptor: THIOREDOXIN PEROXIDASE
Authors:Saccoccia, F, Angelucci, F, Bellelli, A, Boumis, G, Brunori, M, Miele, A.E.
Deposit date:2011-07-25
Release date:2012-03-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin.
Structure, 20, 2012

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