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4YBA
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BU of 4yba by Molmil
The structure of the C.Kpn2I controller protein
Descriptor: GLYCEROL, Regulatory protein C
Authors:Shevtsov, M.B, Martin, R.N, Swiderska, A, McGeehan, G.E, Kneale, G.G.
Deposit date:2015-02-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of the C.kpn2I controller protein
To Be Published
5A7L
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BU of 5a7l by Molmil
TP901-1 CI NTD (res 1-80)
Descriptor: CI
Authors:Frandsen, K.E.H, Rasmussen, K.K, Lo Leggio, L.
Deposit date:2015-07-08
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural and Dynamics Studies of a Truncated Variant of Ci Repressor from Bacteriophage Tp901-1.
Sci.Rep., 6, 2016
7JVT
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BU of 7jvt by Molmil
Crystal structure of a lambda-186 hybrid repressor
Descriptor: OL1 bottom, OL1 top, Repressor protein CI
Authors:Truong, J.Q, Bruning, J.B, Shearwin, K.E.
Deposit date:2020-08-23
Release date:2021-09-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Crystal structure of a hybrid lambda-186 repressor
To Be Published
4RYK
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BU of 4ryk by Molmil
Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e
Descriptor: DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, Lmo0325 protein, ...
Authors:Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-12-15
Release date:2015-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e
To be Published
7ZCV
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BU of 7zcv by Molmil
Rgg144 of Streptococcus pneumoniae
Descriptor: Transcriptional regulator
Authors:Wallis, R, Girija, U.V, Yesilkaya, H.
Deposit date:2022-03-29
Release date:2022-06-01
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-function analysis for the development of peptide inhibitors for a Gram-positive quorum sensing system.
Mol.Microbiol., 117, 2022
6F8S
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BU of 6f8s by Molmil
Toxin-Antitoxin complex GraTA
Descriptor: DI(HYDROXYETHYL)ETHER, Putative Killer protein, SULFATE ION, ...
Authors:Talavera, A, Loris, R.
Deposit date:2017-12-13
Release date:2018-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
1Y9Q
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BU of 1y9q by Molmil
Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae
Descriptor: D-METHIONINE, ZINC ION, transcriptional regulator, ...
Authors:Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-16
Release date:2005-01-04
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae
To be Published
5YCL
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BU of 5ycl by Molmil
Crystal structure of HigBA complex from Shigella flexneri
Descriptor: Antitoxin HigA, mRNA interferase HigB
Authors:Youn, W.S, Seok, S.H, Seo, M.D.
Deposit date:2017-09-07
Release date:2018-09-19
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural changes of antitoxin HigA from Shigella flexneri by binding of its cognate toxin HigB.
Int.J.Biol.Macromol., 130, 2019
1B0N
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BU of 1b0n by Molmil
SINR PROTEIN/SINI PROTEIN COMPLEX
Descriptor: PROTEIN (SINI PROTEIN), PROTEIN (SINR PROTEIN), ZINC ION
Authors:Lewis, R.J, Brannigan, J.A, Offen, W.A, Smith, I, Wilkinson, A.J.
Deposit date:1998-11-11
Release date:1999-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.
J.Mol.Biol., 283, 1998
6TRI
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BU of 6tri by Molmil
CI-MOR repressor-antirepressor complex of the temperate bacteriophage TP901-1 from Lactococcus lactis
Descriptor: CI, MOR, SULFATE ION
Authors:Rasmussen, K.K, Blackledge, M, Herrmann, T, Jensen, M.R, Lo Leggio, L.
Deposit date:2019-12-18
Release date:2020-08-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.277 Å)
Cite:Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.
Proc.Natl.Acad.Sci.USA, 117, 2020
6U0I
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BU of 6u0i by Molmil
Putative Antitoxin HicB3 from Escherichia coli str. K-12 substr. DH10B
Descriptor: Antitoxin HicB, CHLORIDE ION
Authors:Osipiuk, J, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-14
Release date:2019-08-28
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Putative Antitoxin HicB3 from Escherichia coli str. K-12 substr. DH10B
to be published
6W1A
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BU of 6w1a by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2 bound to DNA
Descriptor: DNA (30-MER), GLYCEROL, PHOSPHATE ION, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2020-03-03
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay.
Proc.Natl.Acad.Sci.USA, 117, 2020
5W4N
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BU of 5w4n by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, Transcriptional regulator
Authors:Neiditch, M.B, Khataokar, A.A, Capodagli, G.C.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
5W4M
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BU of 5w4m by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
5IFG
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BU of 5ifg by Molmil
Crystal structure of HigA-HigB complex from E. Coli
Descriptor: Antitoxin HigA, mRNA interferase HigB
Authors:Yang, J.S, Zhou, K, Gao, z.Q, Liu, Q.S, Dong, Y.H.
Deposit date:2016-02-26
Release date:2017-03-01
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structural insight into the E. coli HigBA complex
Biochem. Biophys. Res. Commun., 478, 2016
3WOA
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BU of 3woa by Molmil
Crystal structure of lambda repressor (1-45) fused with maltose-binding protein
Descriptor: Repressor protein CI, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2013-12-25
Release date:2015-04-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Co-translational folding of alpha-helical proteins: structural studies of intermediate-length variants of the lambda repressor.
FEBS Open Bio, 8, 2018
3ZKC
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BU of 3zkc by Molmil
Crystal structure of the master regulator for biofilm formation SinR in complex with DNA.
Descriptor: 5'-D(*AP*AP*AP*GP*TP*TP*CP*TP*CP*TP*TP*TP*AP*GP *AP*GP*AP*AP*CP*AP*AP)-3', 5'-D(*AP*TP*TP*GP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP *AP*GP*AP*AP*CP*TP*TP)-3', HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR
Authors:Newman, J.A, Rodrigues, C, Lewis, R.J.
Deposit date:2013-01-22
Release date:2013-03-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis.
J.Biol.Chem., 288, 2013
5K98
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BU of 5k98 by Molmil
Structure of HipA-HipB-O2-O3 complex
Descriptor: Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ...
Authors:Schumacher, M.
Deposit date:2016-05-31
Release date:2016-06-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
3HZI
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BU of 3hzi by Molmil
Structure of mdt protein
Descriptor: 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ...
Authors:Schumacher, M.A.
Deposit date:2009-06-23
Release date:2009-07-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
4FSC
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BU of 4fsc by Molmil
Crystal Structure of Bacillus thuringiensis PlcR in its apo form
Descriptor: Transcriptional activator PlcR protein
Authors:Grenha, R, Slamti, L, Bouillaut, L, Lereclus, D, Nessler, S.
Deposit date:2012-06-27
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR.
Proc.Natl.Acad.Sci.USA, 110, 2013
5JUB
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BU of 5jub by Molmil
Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS.
Descriptor: ComS, Transcriptional regulator, pComX-for, ...
Authors:Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
5JUF
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BU of 5juf by Molmil
Crystal structure of the apo form of ComR from S. thermophilus.
Descriptor: SULFATE ION, Transcriptional regulator
Authors:Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
6QER
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BU of 6qer by Molmil
Apo Form Of ComR From S. Thermophilus in space group C2
Descriptor: Transcriptional regulator
Authors:Thuillier, J, Nessler, S.
Deposit date:2019-01-08
Release date:2019-02-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.465 Å)
Cite:Molecular dissection of pheromone selectivity in the competence signaling system ComRS of streptococci.
Proc.Natl.Acad.Sci.USA, 117, 2020
3IVP
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BU of 3ivp by Molmil
The structure of a possible transposon-related DNA-binding protein from Clostridium difficile 630.
Descriptor: Putative transposon-related DNA-binding protein, TETRAETHYLENE GLYCOL
Authors:Tan, K, Marshall, N, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-01
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The structure of a possible transposon-related DNA-binding protein from Clostridium difficile 630.
To be Published
7AB5
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BU of 7ab5 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022

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PDB entries from 2024-09-11

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