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1B0N
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BU of 1b0n by Molmil
SINR PROTEIN/SINI PROTEIN COMPLEX
Descriptor: PROTEIN (SINI PROTEIN), PROTEIN (SINR PROTEIN), ZINC ION
Authors:Lewis, R.J, Brannigan, J.A, Offen, W.A, Smith, I, Wilkinson, A.J.
Deposit date:1998-11-11
Release date:1999-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.
J.Mol.Biol., 283, 1998
7ZCV
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BU of 7zcv by Molmil
Rgg144 of Streptococcus pneumoniae
Descriptor: Transcriptional regulator
Authors:Wallis, R, Girija, U.V, Yesilkaya, H.
Deposit date:2022-03-29
Release date:2022-06-01
Last modified:2022-07-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-function analysis for the development of peptide inhibitors for a Gram-positive quorum sensing system.
Mol.Microbiol., 117, 2022
7JVT
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BU of 7jvt by Molmil
Crystal structure of a lambda-186 hybrid repressor
Descriptor: OL1 bottom, OL1 top, Repressor protein CI
Authors:Truong, J.Q, Bruning, J.B, Shearwin, K.E.
Deposit date:2020-08-23
Release date:2021-09-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Crystal structure of a hybrid lambda-186 repressor
To Be Published
5JUB
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BU of 5jub by Molmil
Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS.
Descriptor: ComS, Transcriptional regulator, pComX-for, ...
Authors:Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
5JUF
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BU of 5juf by Molmil
Crystal structure of the apo form of ComR from S. thermophilus.
Descriptor: SULFATE ION, Transcriptional regulator
Authors:Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
5K98
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BU of 5k98 by Molmil
Structure of HipA-HipB-O2-O3 complex
Descriptor: Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ...
Authors:Schumacher, M.
Deposit date:2016-05-31
Release date:2016-06-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
6QER
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BU of 6qer by Molmil
Apo Form Of ComR From S. Thermophilus in space group C2
Descriptor: Transcriptional regulator
Authors:Thuillier, J, Nessler, S.
Deposit date:2019-01-08
Release date:2019-02-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.465 Å)
Cite:Molecular dissection of pheromone selectivity in the competence signaling system ComRS of streptococci.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TRI
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BU of 6tri by Molmil
CI-MOR repressor-antirepressor complex of the temperate bacteriophage TP901-1 from Lactococcus lactis
Descriptor: CI, MOR, SULFATE ION
Authors:Rasmussen, K.K, Blackledge, M, Herrmann, T, Jensen, M.R, Lo Leggio, L.
Deposit date:2019-12-18
Release date:2020-08-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.277 Å)
Cite:Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.
Proc.Natl.Acad.Sci.USA, 117, 2020
6U0I
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BU of 6u0i by Molmil
Putative Antitoxin HicB3 from Escherichia coli str. K-12 substr. DH10B
Descriptor: Antitoxin HicB, CHLORIDE ION
Authors:Osipiuk, J, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-14
Release date:2019-08-28
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Putative Antitoxin HicB3 from Escherichia coli str. K-12 substr. DH10B
to be published
5W4M
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BU of 5w4m by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
5W4N
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BU of 5w4n by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, Transcriptional regulator
Authors:Neiditch, M.B, Khataokar, A.A, Capodagli, G.C.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
6HPC
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BU of 6hpc by Molmil
Crystal structure of the HicB antitoxin from E. coli
Descriptor: Antitoxin HicB
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
5YCL
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BU of 5ycl by Molmil
Crystal structure of HigBA complex from Shigella flexneri
Descriptor: Antitoxin HigA, mRNA interferase HigB
Authors:Youn, W.S, Seok, S.H, Seo, M.D.
Deposit date:2017-09-07
Release date:2018-09-19
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural changes of antitoxin HigA from Shigella flexneri by binding of its cognate toxin HigB.
Int.J.Biol.Macromol., 130, 2019
6HPB
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BU of 6hpb by Molmil
Crystal structure of the E.coli HicAB toxin-antitoxin complex
Descriptor: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
7AB3
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BU of 7ab3 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB5
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BU of 7ab5 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB4
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BU of 7ab4 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
2WIU
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BU of 2wiu by Molmil
Mercury-modified bacterial persistence regulator hipBA
Descriptor: CHLORIDE ION, HTH-TYPE TRANSCRIPTIONAL REGULATOR HIPB, MERCURY (II) ION, ...
Authors:Evdokimov, A, Voznesensky, I, Fennell, K, Anderson, M, Smith, J.F, Fisher, D.A.
Deposit date:2009-05-17
Release date:2009-07-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:New Kinase Regulation Mechanism Found in Hipba: A Bacterial Persistence Switch.
Acta Crystallogr.,Sect.D, 65, 2009
2P5T
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BU of 2p5t by Molmil
Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae
Descriptor: PezT, Putative transcriptional regulator PezA, fragment of PezA helix-turn-helix motif
Authors:Loll, B, Meinhart, A.
Deposit date:2007-03-16
Release date:2007-05-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular and Structural Characterization of the PezAT Chromosomal Toxin-Antitoxin System of the Human Pathogen Streptococcus pneumoniae.
J.Biol.Chem., 282, 2007
2QFC
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BU of 2qfc by Molmil
Crystal Structure of Bacillus thuringiensis PlcR complexed with PapR
Descriptor: C-terminus pentapeptide from PapR protein, DI(HYDROXYETHYL)ETHER, PlcR protein
Authors:Declerck, N, Chaix, D, Rugani, N, Hoh, F, Arold, S.T.
Deposit date:2007-06-27
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria
Proc.Natl.Acad.Sci.Usa, 104, 2007
3SCH
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BU of 3sch by Molmil
Co(II)-HppE with R-HPP
Descriptor: COBALT (II) ION, Epoxidase, [(2R)-2-hydroxypropyl]phosphonic acid
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
3SCG
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BU of 3scg by Molmil
Fe(II)-HppE with R-HPP
Descriptor: Epoxidase, FE (II) ION, [(2R)-2-hydroxypropyl]phosphonic acid
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
3SCF
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BU of 3scf by Molmil
Fe(II)-HppE with S-HPP and NO
Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ...
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
6AF4
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BU of 6af4 by Molmil
Toxin-Antitoxin module from Streptococcus pneumoniae
Descriptor: HigA antitoxin, HigB toxin
Authors:Kang, S.M, Kim, D.H, Jin, C.
Deposit date:2018-08-08
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Toxin-Antitoxin module from Streptococcus pneumoniae
To Be Published
6AF3
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BU of 6af3 by Molmil
Toxin-Antitoxin module from Streptococcus pneumoniae
Descriptor: HigA antitoxin, HigB toxin
Authors:Kang, S.M, Kim, D.H, Jin, C.
Deposit date:2018-08-08
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Toxin-Antitoxin module from Streptococcus pneumoniae
To Be Published

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