6KZ5
| Crystal Structure Analysis of the Csn-B-bounded NUR77 Ligand binding Domain | Descriptor: | Nuclear receptor subfamily 4 group A member 1, ethyl 2-[2-octanoyl-3,5-bis(oxidanyl)phenyl]ethanoate | Authors: | Hong, W, Chen, H, Wu, Q, Lin, T. | Deposit date: | 2019-09-23 | Release date: | 2020-10-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.45 Å) | Cite: | Blocking PPAR gamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proc.Natl.Acad.Sci.USA, 117, 2020
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2IZA
| APOSTREPTAVIDIN PH 2.00 I4122 STRUCTURE | Descriptor: | FORMIC ACID, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZE
| APOSTREPTAVIDIN PH 3.08 I222 COMPLEX | Descriptor: | AMMONIUM ION, CHLORIDE ION, FORMIC ACID, ... | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZD
| APOSTREPTAVIDIN pH 3.0 I222 COMPLEX | Descriptor: | AMMONIUM ION, CHLORIDE ION, IODIDE ION, ... | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZB
| APOSTREPTAVIDIN PH 3.12 I4122 STRUCTURE | Descriptor: | FORMIC ACID, STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZF
| STREPTAVIDIN-BIOTIN PH 4.0 I222 COMPLEX | Descriptor: | BIOTIN, STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZC
| APOSTREPTAVIDIN PH 2.0 I222 COMPLEX | Descriptor: | CHLORIDE ION, SODIUM ION, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2IZK
| STREPTAVIDIN-GLYCOLURIL PH 2.58 I4122 COMPLEX | Descriptor: | ACETATE ION, GLYCOLURIL, STREPTAVIDIN, ... | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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4UP7
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4UPA
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4UP8
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2IZG
| STREPTAVIDIN-BIOTIN PH 2.0 I222 COMPLEX | Descriptor: | BIOTIN, STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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4UP9
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8GRF
| Crystal structure of F-box protein in the ternary complex with adaptor protein Skp1(DL) and its substrate | Descriptor: | 1,2-ETHANEDIOL, Citrate synthase, E3 ubiquitin ligase complex SCF subunit, ... | Authors: | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | Deposit date: | 2022-09-01 | Release date: | 2023-04-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
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8B1S
| co-crystal of SUDV VP40 with salicylic acid | Descriptor: | 2-HYDROXYBENZOIC ACID, Matrix protein VP40 | Authors: | Werner, A.-D, Krapoth, N, Norris, M.J, Heine, A, Klebe, G, Ollmann Saphire, E, Becker, S. | Deposit date: | 2022-09-12 | Release date: | 2023-09-27 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Development of a Crystallographic Screening to Identify Sudan Virus VP40 Ligands. Acs Omega, 9, 2024
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8B2U
| Crystal structure of SUDV VP40 in complex with salicylic acid | Descriptor: | 2-HYDROXYBENZOIC ACID, Matrix protein VP40 | Authors: | Werner, A.-D, Krapoth, N, Norris, M.J, Heine, A, Klebe, G, Ollmann Saphire, E, Becker, S. | Deposit date: | 2022-09-14 | Release date: | 2023-09-27 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Development of a Crystallographic Screening to Identify Sudan Virus VP40 Ligands. Acs Omega, 9, 2024
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3RG2
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5VO4
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5VSR
| ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1 | Descriptor: | Abscisic acid receptor PYL2, MAGNESIUM ION, N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)-1-(2,3,5,6-tetrafluoro-4-methylphenyl)methanesulfonamide, ... | Authors: | Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K. | Deposit date: | 2017-05-12 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.618 Å) | Cite: | Combining chemical and genetic approaches to increase drought resistance in plants. Nat Commun, 8, 2017
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7M9O
| HIV-1 Protease (I84V) in Complex with LR3-48 | Descriptor: | Protease, SULFATE ION, diethyl [(4-{(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-[{4-[(1R)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butyl}phenoxy)methyl]phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.895 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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7M9K
| HIV-1 Protease WT (NL4-3) in Complex with LR3-48 | Descriptor: | Protease, SULFATE ION, diethyl [(4-{(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-[{4-[(1R)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butyl}phenoxy)methyl]phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.838 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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7M9M
| HIV-1 Protease WT (NL4-3) in Complex with LR3-55 | Descriptor: | Protease, SULFATE ION, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-({4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}[(2S)-2-methylbutyl]amino)butyl]phenoxy}methyl)phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.881 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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7MAK
| HIV-1 Protease (I84V) in Complex with PU7 (LR3-67) | Descriptor: | Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{(2-ethylbutyl)[(4-methoxyphenyl)sulfonyl]amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.972 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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7MAJ
| HIV-1 Protease (I84V) in Complex with PU6 (LR3-66) | Descriptor: | Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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7MAG
| HIV-1 Protease (I84V) in Complex with PU3 (LR3-69) | Descriptor: | Protease, SULFATE ION, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)butyl]phenoxy}methyl)phosphonate | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | HIV-1 Protease in Complex with ligands To Be Published
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