PDB: 17137 resultsInfo pagesStatus searchChemie searchBIRD

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1ZQH	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF A SODIUM-FREE ARTIFICIAL MOTHER LIQUOR AT PH 7.5 Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQI	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), POTASSIUM ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQT	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (0.01 MILLIMOLAR) AND ZNCL2 (0.02 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.4 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
1ZQC	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) Descriptor: CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQN	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF BACL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) Descriptor: BARIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQG	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF A SODIUM-FREE ARTIFICIAL MOTHER LIQUOR AT PH 6.5 Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQS	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF TLCL (0.5 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQP	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (75 MILLIMOLAR) AND NACL (75 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), POTASSIUM ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQO	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQR	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF NICL2 Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), NICKEL (II) ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQB	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF BACL2 (150 MILLIMOLAR) Descriptor: BARIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) AND MGCL2 (15 MILLIMOLAR) Descriptor: CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQF	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CSCL (150 MILLIMOLAR) Descriptor: CESIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQA	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) AT PH 7.5 Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), POTASSIUM ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQM	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), MANGANESE (II) ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQK	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (75 MILLIMOLAR) AND MGCL2 (75 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), POTASSIUM ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (SATURATED SOLUTION) Descriptor: CHROMIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-04-12 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQQ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), MANGANESE (II) ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-12 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
2MB0	Solution structure of hnRNP G RRM in complex with the RNA 5'-AUCAAA-3' Descriptor: RNA-binding motif protein, X chromosome, RNA_(5'-R(*AP*UP*CP*AP*AP*A)-3') Authors: Moursy, A, Allain, F.H.-T, Clery, A. Deposit date: 2013-07-22 Release date: 2014-04-09 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation. Nucleic Acids Res., 42, 2014
2O36	Crystal structure of engineered thimet oligopeptidase with neurolysin specificity in neurotensin cleavage site Descriptor: Thimet oligopeptidase, ZINC ION Authors: Rodgers, D.W, Lim, E.J. Deposit date: 2006-11-30 Release date: 2007-01-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase. J.Biol.Chem., 282, 2007
4HVC	Crystal structure of human prolyl-tRNA synthetase in complex with halofuginone and ATP analogue Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Bifunctional glutamate/proline--tRNA ligase, MAGNESIUM ION, ... Authors: Zhou, H, Sun, L, Yang, X.L, Schimmel, P. Deposit date: 2012-11-06 Release date: 2013-01-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. Nature, 494, 2012
7SLA	CryoEM structure of SGLT1 at 3.15 Angstrom resolution Descriptor: CHOLESTEROL HEMISUCCINATE, Sodium/glucose cotransporter 1, nanobody Nb1 Authors: Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G. Deposit date: 2021-10-23 Release date: 2021-12-15 Last modified: 2022-01-26 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Structure and mechanism of the SGLT family of glucose transporters. Nature, 601, 2022
7SL8	CryoEM structure of SGLT1 at 3.4 A resolution Descriptor: CHOLESTEROL, Sodium/glucose cotransporter 1, nanobody Nb1 Authors: Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G. Deposit date: 2021-10-23 Release date: 2021-12-15 Last modified: 2022-01-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and mechanism of the SGLT family of glucose transporters. Nature, 601, 2022
6F78	Potent and selective Aldo-Keto Reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: Application of a Bioisosteric Scaffold Hopping Approach to Flufenamic acid Descriptor: 4-[[3,5-bis(trifluoromethyl)phenyl]amino]-1,2-benzoxazol-3-one, Aldo-keto reductase family 1 member C3, CHLORIDE ION, ... Authors: Goyal, P, Wahlgren, W.Y, Friemann, R. Deposit date: 2017-12-07 Release date: 2018-04-04 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid. Eur J Med Chem, 150, 2018
4JWM	Ternary complex of D256E mutant of DNA Polymerase Beta Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Perera, L, Ping, L, Shock, D.D, Beard, W.A, Pedersen, L.C, Pedersen, L.G, Wilson, S.H. Deposit date: 2013-03-27 Release date: 2013-06-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Amino Acid Substitution in the Active Site of DNA Polymerase beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction. J.Am.Chem.Soc., 135, 2013

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