7TLP
 
 | | Structure of Atopobium parvulum SufS K235R | | Descriptor: | Cysteine desulfurase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | | Authors: | Karunakaran, G, Couture, J.F. | | Deposit date: | 2022-01-18 | | Release date: | 2022-02-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
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7TLQ
 | | Structure of Atopobium parvulum SufS C375S | | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Karunakaran, G, Couture, J.F. | | Deposit date: | 2022-01-18 | | Release date: | 2022-02-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
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6O11
 | | E. coli cysteine desulfurase SufS C364A with a Cys-aldimine intermediate | | Descriptor: | CHLORIDE ION, Cysteine desulfurase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | | Authors: | Dunkle, J.A, Frantom, P.A. | | Deposit date: | 2019-02-17 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
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6O10
 | | E. coli cysteine desulfurase SufS | | Descriptor: | CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Dunkle, J.A, Frantom, P.A. | | Deposit date: | 2019-02-17 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
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6O13
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4AZK
 | | Structural basis of L-phosphoserine binding to Bacillus alcalophilus phosphoserine aminotransferase | | Descriptor: | CHLORIDE ION, PHOSPHOSERINE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Battula, P, Dubnovitsky, A.P, Papageorgiou, A.C. | | Deposit date: | 2012-06-26 | | Release date: | 2013-05-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.595 Å) | | Cite: | Structural Basis of L-Phosphoserine Binding to Bacillus Alcalophilus Phosphoserine Aminotransferase
Acta Crystallogr.,Sect.D, 69, 2013
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3ZRP
 | | Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from Sulfolobus solfataricus | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SERINE-PYRUVATE AMINOTRANSFERASE (AGXT) | | Authors: | Sayer, C, Bommer, M, Isupov, M.N, Ward, J, Littlechild, J. | | Deposit date: | 2011-06-17 | | Release date: | 2012-06-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structure and Substrate Specificity of the Thermophilic Serine:Pyruvate Aminotransferase from Sulfolobus Solfataricus
Acta Crystallogr.,Sect.D, 68, 2012
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4AZJ
 | | Structural basis of L-phosphoserine binding to Bacillus alcalophilus phosphoserine aminotransferase | | Descriptor: | CHLORIDE ION, PHOSPHOSERINE, PHOSPHOSERINE AMINOTRANSFERASE, ... | | Authors: | Battula, P, Dubnovitsky, A.P, Papageorgiou, A.C. | | Deposit date: | 2012-06-26 | | Release date: | 2013-05-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Basis of L-Phosphoserine Binding to Bacillus Alcalophilus Phosphoserine Aminotransferase
Acta Crystallogr.,Sect.D, 69, 2013
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3ZRR
 | | Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from Sulfolobus solfataricus | | Descriptor: | 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, CALCIUM ION, SERINE-PYRUVATE AMINOTRANSFERASE (AGXT) | | Authors: | Sayer, C, Bommer, M, Isupov, M.N, Ward, J, Littlechild, J. | | Deposit date: | 2011-06-17 | | Release date: | 2012-06-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Crystal Structure and Substrate Specificity of the Thermophilic Serine:Pyruvate Aminotransferase from Sulfolobus Solfataricus
Acta Crystallogr.,Sect.D, 68, 2012
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3ZRQ
 | | Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from Sulfolobus solfataricus | | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, SERINE-PYRUVATE AMINOTRANSFERASE (AGXT) | | Authors: | Sayer, C, Bommer, M, Isupov, M.N, Ward, J, Littlechild, J. | | Deposit date: | 2011-06-17 | | Release date: | 2012-06-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure and Substrate Specificity of the Thermophilic Serine:Pyruvate Aminotransferase from Sulfolobus Solfataricus
Acta Crystallogr.,Sect.D, 68, 2012
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4CBR
 | | X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM) | | Descriptor: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SERINE--PYRUVATE AMINOTRANSFERASE | | Authors: | Yunta, C, Albert, A. | | Deposit date: | 2013-10-16 | | Release date: | 2014-07-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase.
Biochem.J., 462, 2014
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4CBS
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6KFZ
 | | SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec at 1.96 angstrom resolution | | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 287, 2020
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6KFY
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6KG1
 | | NifS from Helicobacter pylori, soaked with L-cysteine for 180 sec | | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, CHLORIDE ION, Cysteine desulfurase IscS, ... | | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 287, 2020
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6KG0
 | | NifS from Helicobacter pylori, soaked with L-cysteine for 118 sec | | Descriptor: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 287, 2020
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6MFB
 | | Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase | | Authors: | Maciel, L.G, Oliveira, A.A, Romao, T.P, Silva Filha, M.H.N.L, dos Anjos, J.V, Soares, T.A, Guido, R.V.C. | | Deposit date: | 2018-09-10 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti
To Be Published
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6MRH
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6MRE
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6MRI
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7XEJ
 | | SufS with D-cysteine for 5 min | | Descriptor: | (2~{S})-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-propanoic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ... | | Authors: | Nakamiura, R, Fujishiro, T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
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7XEK
 | | SufS with D-cysteine for 6 h | | Descriptor: | (2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ... | | Authors: | Nakamura, R, Fujishiro, T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
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7XEN
 | | SufS with L-penicillamine | | Descriptor: | (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, Cysteine desulfurase SufS | | Authors: | Nakamura, R, Fujishiro, T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
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7XET
 | | SufS with beta-cyano-L-alanine | | Descriptor: | (2~{E})-3-cyano-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylimino]propanoic acid, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Nakamura, R, Fujishiro, T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Inhibition mechanism of SufS by L-propargylglycine
to be published
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7XES
 | | NifS with L-penicillamine | | Descriptor: | (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, CHLORIDE ION, Cysteine desulfurase IscS, ... | | Authors: | Nakamura, R, Fujishiro, T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
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