5U30
 
 | | Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex | | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | Deposit date: | 2016-12-01 | | Release date: | 2017-01-25 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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3K3W
 | | Thermostable Penicillin G acylase from Alcaligenes faecalis in orthorhombic form | | Descriptor: | CALCIUM ION, Penicillin G acylase | | Authors: | Varshney, N.K, Kumar, R.S, Ignatova, Z, Dodson, E, Suresh, C.G. | | Deposit date: | 2009-10-05 | | Release date: | 2009-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis.
Acta Crystallogr.,Sect.F, 68, 2012
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3K4C
 | | Pyranose 2-oxidase H167A/T169G mutant | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... | | Authors: | Divne, C, Tan, T.C. | | Deposit date: | 2009-10-05 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase.
J.Biol.Chem., 285, 2010
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3BT0
 | | Crystal structure of transthyretin variant V20S | | Descriptor: | Transthyretin | | Authors: | Zanotti, G, Folli, C, Cendron, L, Gliubich, F, Negro, A, Berni, R. | | Deposit date: | 2007-12-27 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
Febs J., 275, 2008
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5TUG
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9EU5
 | | SSX structure of Autotaxin at room temperature | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, CALCIUM ION, ... | | Authors: | Eymery, M.C, McCarthy, A.A, Foos, N, Basu, S. | | Deposit date: | 2024-03-27 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | In situ serial crystallography facilitates 96-well plate structural analysis at low symmetry.
Iucrj, 2024
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9LDT
 | | DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK | | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... | | Authors: | Dunn, C.R, Holbrook, J.J, Muirhead, H. | | Deposit date: | 1991-11-26 | | Release date: | 1993-10-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design and synthesis of new enzymes based on the lactate dehydrogenase framework.
Philos.Trans.R.Soc.London,Ser.B, 332, 1991
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6MSE
 | | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | | Authors: | Mao, Y.D. | | Deposit date: | 2018-10-16 | | Release date: | 2018-11-21 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
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3BVX
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9ENT
 | | SSX structure of Autotaxin in cryogenic conditions | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, CALCIUM ION, ... | | Authors: | Eymery, M.C, McCarthy, A.A, Foos, N, Basu, S. | | Deposit date: | 2024-03-13 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | In situ serial crystallography facilitates 96-well plate structural analysis at low symmetry.
Iucrj, 2024
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3JTR
 | | Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis | | Descriptor: | GLYCEROL, Glutaryl 7-aminocephalosporanic acid acylase | | Authors: | Cho, K.J, Kim, J.K, Lee, J.H, Shin, H.J, Park, S.S, Kim, K.H. | | Deposit date: | 2009-09-14 | | Release date: | 2010-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural features of cephalosporin acylase reveal the basis of autocatalytic activation.
Biochem.Biophys.Res.Commun., 390, 2009
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3BWE
 | | Crystal structure of aggregated form of DJ1 | | Descriptor: | PHOSPHATE ION, Protein DJ-1 | | Authors: | Cha, S.S. | | Deposit date: | 2008-01-09 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner.
J.Biol.Chem., 283, 2008
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9LDB
 | | DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK | | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... | | Authors: | Dunn, C.R, Holbrook, J.J, Muirhead, H. | | Deposit date: | 1991-11-26 | | Release date: | 1993-10-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Design and synthesis of new enzymes based on the lactate dehydrogenase framework.
Philos.Trans.R.Soc.London,Ser.B, 332, 1991
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9LYZ
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3K1O
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole | | Descriptor: | 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-6-O-{4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenyl}-1-(1H-1,2,4-triazol-1-yl)-D-erythro-hexitol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase | | Authors: | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | Deposit date: | 2009-09-28 | | Release date: | 2009-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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7YPE
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3C3N
 | | Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y | | Descriptor: | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | Authors: | Pinheiro, M.P, Iulek, J, Nonato, M.C. | | Deposit date: | 2008-01-28 | | Release date: | 2008-04-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain
Biochem.Biophys.Res.Commun., 369, 2008
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3K4M
 | | Pyranose 2-oxidase Y456W mutant in complex with 2FG | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Divne, C, Tan, T.C. | | Deposit date: | 2009-10-05 | | Release date: | 2010-05-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase.
Febs J., 277, 2010
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3C61
 | | Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani | | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, AZIDE ION, CHLORIDE ION, ... | | Authors: | Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | | Deposit date: | 2008-02-01 | | Release date: | 2008-02-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Dihydroorotate dehydrogenase from Leishmania donovani.
To be Published
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7YPF
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3K70
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3JQZ
 | | Crystal Structure of Human serum albumin complexed with Lidocaine | | Descriptor: | 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide, Serum albumin | | Authors: | Hein, K.L, Kragh-Hansen, U, Morth, J.P, Nissen, P. | | Deposit date: | 2009-09-08 | | Release date: | 2010-04-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 2010
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3K92
 | | Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG | | Descriptor: | DI(HYDROXYETHYL)ETHER, NAD-specific glutamate dehydrogenase | | Authors: | Gunka, K, Newman, J.A, Commichau, F.M, Herzberg, C, Rodrigues, C, Hewitt, L, Lewis, R.J, Stulke, J. | | Deposit date: | 2009-10-15 | | Release date: | 2010-06-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties
J.Mol.Biol., 400, 2010
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3C75
 | | Paracoccus versutus methylamine dehydrogenase in complex with amicyanin | | Descriptor: | Amicyanin, COPPER (II) ION, Methylamine dehydrogenase heavy chain, ... | | Authors: | Cavalieri, C, Biermann, N, Vlasie, M.D, Einsle, O, Merli, A, Ferrari, D, Rossi, G.L, Ubbink, M. | | Deposit date: | 2008-02-06 | | Release date: | 2008-12-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural comparison of crystal and solution states of the 138 kDa complex of methylamine dehydrogenase and amicyanin from Paracoccus versutus.
Biochemistry, 47, 2008
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3BLX
 | | Yeast Isocitrate Dehydrogenase (Apo Form) | | Descriptor: | Isocitrate dehydrogenase [NAD] subunit 1, Isocitrate dehydrogenase [NAD] subunit 2 | | Authors: | Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L. | | Deposit date: | 2007-12-11 | | Release date: | 2008-02-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
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