2FIP
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![BU of 2fip by Molmil](/molmil-images/mine/2fip) | Phage phi29 transcription regulator p4 | Descriptor: | Late genes activator | Authors: | Badia, D, Camacho, A, Perez-Lago, L, Escandon, C, Salas, M, Coll, M. | Deposit date: | 2005-12-30 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of phage phi29 transcription regulator p4-DNA complex reveals an N-hook motif for DNA Mol.Cell, 22, 2006
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5LN5
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5X5L
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![BU of 5x5l by Molmil](/molmil-images/mine/5x5l) | Crystal structure of response regulator AdeR DNA binding domain in complex with an intercistronic region | Descriptor: | AdeR, DNA (5'-D(P*TP*AP*AP*AP*GP*TP*GP*TP*GP*GP*AP*GP*TP*AP*AP*GP*TP*GP*TP*GP*GP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*CP*CP*AP*CP*AP*CP*TP*TP*AP*CP*TP*CP*CP*AP*CP*AP*CP*TP*TP*TP*A)-3') | Authors: | Wen, Y. | Deposit date: | 2017-02-16 | Release date: | 2017-08-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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1F43
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![BU of 1f43 by Molmil](/molmil-images/mine/1f43) | SOLUTION STRUCTURE OF THE MATA1 HOMEODOMAIN | Descriptor: | MATING-TYPE PROTEIN A-1 | Authors: | Anderson, J.S, Forman, M, Modleski, S, Dahlquist, F.W, Baxter, S.M. | Deposit date: | 2000-06-07 | Release date: | 2000-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Cooperative ordering in homeodomain-DNA recognition: solution structure and dynamics of the MATa1 homeodomain. Biochemistry, 39, 2000
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3A02
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![BU of 3a02 by Molmil](/molmil-images/mine/3a02) | Crystal structure of Aristaless homeodomain | Descriptor: | CADMIUM ION, CHLORIDE ION, Homeobox protein aristaless | Authors: | Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. | Deposit date: | 2009-02-28 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
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4IBY
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![BU of 4iby by Molmil](/molmil-images/mine/4iby) | Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation S240R | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, ZINC ION | Authors: | Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. | Deposit date: | 2012-12-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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4IBQ
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![BU of 4ibq by Molmil](/molmil-images/mine/4ibq) | Human p53 core domain with hot spot mutation R273C | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... | Authors: | Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. | Deposit date: | 2012-12-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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4IJT
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![BU of 4ijt by Molmil](/molmil-images/mine/4ijt) | Human p53 core domain with hot spot mutation R273H (form II) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cellular tumor antigen p53, ... | Authors: | Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. | Deposit date: | 2012-12-23 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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4IBZ
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![BU of 4ibz by Molmil](/molmil-images/mine/4ibz) | Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... | Authors: | Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. | Deposit date: | 2012-12-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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7LSY
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![BU of 7lsy by Molmil](/molmil-images/mine/7lsy) | NHEJ Short-range synaptic complex | Descriptor: | DNA (26-MER), DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3'), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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2LTD
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![BU of 2ltd by Molmil](/molmil-images/mine/2ltd) | Solution NMR Structure of apo YdbC from Lactococcus lactis, Northeast Structural Genomics Consortium (NESG) Target KR150 | Descriptor: | Uncharacterized protein ydbC | Authors: | Rossi, P, Barbieri, C.M, Aramini, J.M, Bini, E, Lee, H, Janjua, H, Ciccosanti, C, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-16 | Release date: | 2012-06-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome. Nucleic Acids Res., 41, 2013
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4U77
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![BU of 4u77 by Molmil](/molmil-images/mine/4u77) | BTB domain from Drosophila CP190 | Descriptor: | Centrosome-associated zinc finger protein CP190, DIMETHYL SULFOXIDE, GLYCEROL | Authors: | Allemand, F, Cohen-Gonsaud, M, Labesse, G, Nollmann, M. | Deposit date: | 2014-07-30 | Release date: | 2014-08-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome. Plos Genet., 10, 2014
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7SZQ
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![BU of 7szq by Molmil](/molmil-images/mine/7szq) | Human P300 complexed with an azaindazole inhibitor | Descriptor: | 1-[1-(4-chlorophenyl)cyclopentane-1-carbonyl]-N-1H-pyrazolo[4,3-b]pyridin-5-yl-D-prolinamide, Histone acetyltransferase p300 | Authors: | Shewchuk, L.M, Reid, R.A. | Deposit date: | 2021-11-29 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
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7SSK
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![BU of 7ssk by Molmil](/molmil-images/mine/7ssk) | Human P300 complexed with a glycine-based inhibitor | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Histone acetyltransferase p300, ... | Authors: | Shewchuk, L.M, Reid, R.A. | Deposit date: | 2021-11-11 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
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7SS8
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![BU of 7ss8 by Molmil](/molmil-images/mine/7ss8) | Human P300 complexed with a proline-based inhibitor | Descriptor: | 1,2-ETHANEDIOL, 1-[1-(4-chlorophenyl)cyclopentane-1-carbonyl]-N-{[3-(methylcarbamoyl)phenyl]methyl}-D-prolinamide, Histone acetyltransferase p300, ... | Authors: | Shewchuk, L.M, Reid, R.A. | Deposit date: | 2021-11-10 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
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4IBS
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![BU of 4ibs by Molmil](/molmil-images/mine/4ibs) | Human p53 core domain with hot spot mutation R273H (form I) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, ZINC ION | Authors: | Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. | Deposit date: | 2012-12-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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4IBT
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![BU of 4ibt by Molmil](/molmil-images/mine/4ibt) | Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Diskin-Posner, Y, Eldar, A, Rozenberg, H, Shakked, Z. | Deposit date: | 2012-12-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
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5J0N
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![BU of 5j0n by Molmil](/molmil-images/mine/5j0n) | Lambda excision HJ intermediate | Descriptor: | Excisionase, Integrase, Integration host factor subunit alpha, ... | Authors: | Van Duyne, G, Grigorieff, N, Landy, A. | Deposit date: | 2016-03-28 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction. Elife, 5, 2016
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3D08
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![BU of 3d08 by Molmil](/molmil-images/mine/3d08) | Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Suad, O, Rozenberg, H, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
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1AOY
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3D05
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![BU of 3d05 by Molmil](/molmil-images/mine/3d05) | Human p53 core domain with hot spot mutation R249S (II) | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Suad, O, Rozenberg, H, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
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6YJ2
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![BU of 6yj2 by Molmil](/molmil-images/mine/6yj2) | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism | Descriptor: | GLYCEROL, Probable transcriptional regulatory protein (Probably TetR-family) | Authors: | Keep, N.H, Pritchard, J.E, Sula, A, Cole, A.R, Kendall, S.L. | Deposit date: | 2020-04-02 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism To be published
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3D07
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6ZA3
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![BU of 6za3 by Molmil](/molmil-images/mine/6za3) | Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (C2221 space group) | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Morera, S, Vigouroux, A, Legrand, P. | Deposit date: | 2020-06-04 | Release date: | 2020-12-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic Acids Res., 49, 2021
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4FE7
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![BU of 4fe7 by Molmil](/molmil-images/mine/4fe7) | structure of xylose-binding transcription activator xylR | Descriptor: | Xylose operon regulatory protein, alpha-D-xylopyranose | Authors: | Ni, L, Schumacher, M.A. | Deposit date: | 2012-05-29 | Release date: | 2012-12-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain. Nucleic Acids Res., 41, 2013
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