2KPU
 
 | | NMR Structure of YbbR family protein Dhaf_0833 (residues 32-118) from Desulfitobacterium hafniense DCB-2: Northeast Structural Genomics Consortium target DhR29B | | Descriptor: | YbbR family protein | | Authors: | Cort, J.R, Ramelot, T.A, Yang, Y, Belote, R.L, Ciccosanti, C, Haleema, J, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-10-20 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structures of domains I and IV from YbbR are representative of a widely distributed protein family.
Protein Sci., 20, 2011
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2KQB
 | | First PBZ domain of human APLF protein | | Descriptor: | Aprataxin and PNK-like factor, ZINC ION | | Authors: | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | | Deposit date: | 2009-11-04 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
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2KUR
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2KUV
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2KOM
 | | Solution structure of humar Par-3b PDZ2 (residues 451-549) | | Descriptor: | Partitioning defective 3 homolog | | Authors: | Volkman, B.F, Tyler, R.C, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2009-09-24 | | Release date: | 2009-11-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Rapid, robotic, small-scale protein production for NMR screening and structure determination.
Protein Sci., 19, 2010
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2KPL
 | | MAGI-1 PDZ1 / E6CT | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6 | | Authors: | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | Deposit date: | 2009-10-16 | | Release date: | 2010-10-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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2KPK
 | | MAGI-1 PDZ1 | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | | Authors: | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | Deposit date: | 2009-10-16 | | Release date: | 2010-10-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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2KYM
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2KNZ
 | | NMR structure of CIP75 UBA domain | | Descriptor: | Ubiquilin-4 | | Authors: | Kieken, F, Spagnol, G, Su, V, Lau, A.F, Sorgen, P.L. | | Deposit date: | 2009-09-08 | | Release date: | 2010-03-16 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure note: UBA domain of CIP75.
J.Biomol.Nmr, 46, 2010
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2KQD
 | | First PBZ domain of human APLF protein in complex with ribofuranosyladenosine | | Descriptor: | ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ... | | Authors: | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | | Deposit date: | 2009-11-04 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
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2KUO
 | | Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response | | Descriptor: | Aprataxin and PNK-like factor, ZINC ION | | Authors: | Li, G.Y, McCulloch, R.D, Fenton, A, Cheung, M, Meng, L, Ikura, M, Koch, C.A. | | Deposit date: | 2010-02-23 | | Release date: | 2010-05-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response
To be Published
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2KUU
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2KQE
 | | Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine | | Descriptor: | ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ... | | Authors: | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | | Deposit date: | 2009-11-04 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
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5LKN
 | | NMR solution structure of human FNIII domain 2 of NCAM | | Descriptor: | Neural cell adhesion molecule 1 | | Authors: | Slapsak, U, Salzano, G, Amin, L, Abskharon, R.N.N, Ilc, G, Zupancic, B, Biljan, I, Plavec, J, Giachin, G, Legname, G. | | Deposit date: | 2016-07-22 | | Release date: | 2016-09-14 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain.
J.Biol.Chem., 291, 2016
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4BKW
 | | Crystal structure of the C-terminal region of human ZFYVE9 | | Descriptor: | 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 | | Authors: | Williams, E, Krojer, T, Vollmar, M, Shrestha, L, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | | Deposit date: | 2013-04-30 | | Release date: | 2013-05-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Crystal Structure of the C-Terminal Region of Human Zfyve9
Ph D Thesis, 2013
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4D10
 | | Crystal structure of the COP9 signalosome | | Descriptor: | COP9 SIGNALOSOME COMPLEX SUBUNIT 1, COP9 SIGNALOSOME COMPLEX SUBUNIT 2, COP9 SIGNALOSOME COMPLEX SUBUNIT 3, ... | | Authors: | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | | Deposit date: | 2014-04-30 | | Release date: | 2014-07-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal Structure of the Human Cop9 Signalosome
Nature, 512, 2014
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6A73
 | | Complex structure of CSN2 with IP6 | | Descriptor: | COP9 signalosome complex subunit 2,Endolysin, INOSITOL HEXAKISPHOSPHATE, SULFATE ION | | Authors: | Liu, L, Li, D, Rao, F, Wang, T. | | Deposit date: | 2018-07-02 | | Release date: | 2019-07-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.447 Å) | | Cite: | Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5OOQ
 | | Structure of the Mtr4 Nop53 Complex | | Descriptor: | ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION | | Authors: | Falk, S, Basquin, J, Conti, E. | | Deposit date: | 2017-08-08 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
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2WZ9
 | | Crystal structure of the thioredoxin domain of human TXNL2 | | Descriptor: | GLUTAREDOXIN-3 | | Authors: | Vollmar, M, Johannson, C, Cocking, R, Pike, A.C.W, Muniz, J.R.C, Edwards, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Kavanagh, K.L. | | Deposit date: | 2009-11-25 | | Release date: | 2010-03-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structure of the Thioredoxin Domain of Human Txnl2
To be Published
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7Z36
 | | Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain | | Descriptor: | Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta, SMARCAD1 CUE1 domain, ZINC ION, ... | | Authors: | Stoll, G.A, Modis, Y. | | Deposit date: | 2022-03-01 | | Release date: | 2022-11-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure and functional mapping of the KRAB-KAP1 repressor complex.
Embo J., 41, 2022
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6PJ2
 | | Crystal structure of HCV NS3/4A D168A protease in complex with P4-P5-4 (AJ-65) | | Descriptor: | (2R,6S,12Z,13aS,14aR,16aS)-6-[(N-acetyl-L-isoleucyl)amino]-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-N-[(1-methylcyclo propyl)sulfonyl]-5,16-dioxo-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacycl opentadecine-14a(5H)-carboxamide, 1,2-ETHANEDIOL, NS3 protease, ... | | Authors: | Zephyr, J, Schiffer, C.A. | | Deposit date: | 2019-06-27 | | Release date: | 2020-03-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Mbio, 11, 2020
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6PIU
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6PIY
 | | Crystal structure of HCV NS3/4A D168A protease in complex with P4-2 (NR02-61) | | Descriptor: | 1,2-ETHANEDIOL, 1-methylcyclobutyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4A protease, ... | | Authors: | Zephyr, J, Schiffer, C.A. | | Deposit date: | 2019-06-27 | | Release date: | 2020-03-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.862 Å) | | Cite: | Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Mbio, 11, 2020
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6PIX
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4B1M
 | | CARBOHYDRATE BINDING MODULE CBM66 FROM BACILLUS SUBTILIS | | Descriptor: | LEVANASE, SODIUM ION, SULFATE ION, ... | | Authors: | Cuskin, F, Flint, J.E, Morland, C, Basle, A, Henrissat, B, Countinho, P.M, Strazzulli, A, Solzehinkin, A, Davies, G.J, Gilbert, H.J, Gloster, T.M. | | Deposit date: | 2012-07-11 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | How Nature Can Exploit Nonspecific Catalytic and Carbohydrate Binding Modules to Create Enzymatic Specificity
Proc.Natl.Acad.Sci.USA, 109, 2012
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