8H9B
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![BU of 8h9b by Molmil](/molmil-images/mine/8h9b) | Crystal structure of chemically modified E. coli ThrS catalytic domain 3 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8CDB
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![BU of 8cdb by Molmil](/molmil-images/mine/8cdb) | Proulilysin E229A structure | Descriptor: | CALCIUM ION, Ulilysin, ZINC ION | Authors: | Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X. | Deposit date: | 2023-01-30 | Release date: | 2023-03-22 | Last modified: | 2023-03-29 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases. Dalton Trans, 52, 2023
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6XYW
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![BU of 6xyw by Molmil](/molmil-images/mine/6xyw) | Structure of the plant mitochondrial ribosome | Descriptor: | 28S ribosomal S34 protein, 3-hydroxyisobutyryl-CoA hydrolase-like protein 2, mitochondrial, ... | Authors: | Soufari, H, Waltz, F, Bochler, A, Giege, P, Hashem, Y. | Deposit date: | 2020-01-31 | Release date: | 2020-04-15 | Last modified: | 2020-04-29 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Cryo-EM structure of the RNA-rich plant mitochondrial ribosome. Nat.Plants, 6, 2020
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1INH
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![BU of 1inh by Molmil](/molmil-images/mine/1inh) | INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA111 INHIBITOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-[(AMINOACETYL)AMINO]BENZOIC ACID, CALCIUM ION, ... | Authors: | Jedrzejas, M.J, Luo, M. | Deposit date: | 1995-07-07 | Release date: | 1996-08-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction. J.Med.Chem., 38, 1995
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6ER6
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![BU of 6er6 by Molmil](/molmil-images/mine/6er6) | Crystal structure of a computationally designed colicin endonuclease and immunity pair colEdes7/Imdes7 | Descriptor: | Endonuclease colEdes7, immunity Imdes7 | Authors: | Netzer, R, Listov, D, Dym, O, Albeck, S, Knop, O, Fleishman, S.J. | Deposit date: | 2017-10-17 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Ultrahigh specificity in a network of computationally designed protein-interaction pairs. Nat Commun, 9, 2018
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8C9K
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![BU of 8c9k by Molmil](/molmil-images/mine/8c9k) | |
8H9A
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![BU of 8h9a by Molmil](/molmil-images/mine/8h9a) | Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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1BHM
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![BU of 1bhm by Molmil](/molmil-images/mine/1bhm) | RESTRICTION ENDONUCLEASE BAMHI COMPLEX WITH DNA | Descriptor: | DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), PROTEIN (BAMHI (E.C.3.1.21.4)) | Authors: | Aggarwal, A.K, Newman, M. | Deposit date: | 1995-07-12 | Release date: | 1995-07-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Bam HI endonuclease bound to DNA: partial folding and unfolding on DNA binding. Science, 269, 1995
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1BDW
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8C4J
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![BU of 8c4j by Molmil](/molmil-images/mine/8c4j) | CdaA-compound 4 complex | Descriptor: | 5-methylpyrimidin-4-amine, CHLORIDE ION, Diadenylate cyclase | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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8C4N
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![BU of 8c4n by Molmil](/molmil-images/mine/8c4n) | CdaA-AMP complex | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Diadenylate cyclase, ... | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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8C4Q
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![BU of 8c4q by Molmil](/molmil-images/mine/8c4q) | CdaA-Apo | Descriptor: | CHLORIDE ION, Diadenylate cyclase | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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8C4O
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![BU of 8c4o by Molmil](/molmil-images/mine/8c4o) | CdaA-ATP complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Diadenylate cyclase, ... | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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8C4R
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![BU of 8c4r by Molmil](/molmil-images/mine/8c4r) | CdaA-adenine complex | Descriptor: | ADENINE, CHLORIDE ION, Diadenylate cyclase | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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2ZHB
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![BU of 2zhb by Molmil](/molmil-images/mine/2zhb) | Complex structure of AFCCA with tRNAminiDUC | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | Authors: | Toh, Y, Tomita, K. | Deposit date: | 2008-02-01 | Release date: | 2008-08-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme Embo J., 27, 2008
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4Q7E
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![BU of 4q7e by Molmil](/molmil-images/mine/4q7e) | Non-phosphorylated HemR Receiver Domain from Leptospira biflexa | Descriptor: | GLYCEROL, Response regulator of a two component regulatory system, SULFATE ION | Authors: | Morero, N.R, Buschiazzo, A. | Deposit date: | 2014-04-24 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.441 Å) | Cite: | HemR is an OmpR/PhoB-like response regulator from Leptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes. Mol.Microbiol., 94, 2014
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6XRE
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![BU of 6xre by Molmil](/molmil-images/mine/6xre) | Structure of the p53/RNA polymerase II assembly | Descriptor: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | Deposit date: | 2020-07-12 | Release date: | 2021-03-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of the p53/RNA polymerase II assembly. Commun Biol, 4, 2021
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1B9T
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![BU of 1b9t by Molmil](/molmil-images/mine/1b9t) | NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE | Descriptor: | 1-(4-CARBOXY-2-GUANIDINOPENTYL)-5,5'-DI(HYDROXYMETHYL)PYRROLIDIN-2-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Finley, J.B, Atigadda, V.R, Duarte, F, Zhao, J.J, Brouillette, W.J, Air, G.M, Luo, M. | Deposit date: | 1999-02-15 | Release date: | 1999-02-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J.Mol.Biol., 293, 1999
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8CBR
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![BU of 8cbr by Molmil](/molmil-images/mine/8cbr) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BDM-2 | Descriptor: | (2S)-2-[3-cyclopropyl-2-(3,4-dihydro-2H-chromen-6-yl)-6-methyl-phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | Deposit date: | 2023-01-25 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBU
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![BU of 8cbu by Molmil](/molmil-images/mine/8cbu) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT884 | Descriptor: | (2S)-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2H-chromen-6-yl)phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | Deposit date: | 2023-01-25 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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8CBV
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![BU of 8cbv by Molmil](/molmil-images/mine/8cbv) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT916 | Descriptor: | (2~{S})-2-[3-cyclopropyl-2-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | Deposit date: | 2023-01-25 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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1X1Y
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![BU of 1x1y by Molmil](/molmil-images/mine/1x1y) | |
8C4M
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![BU of 8c4m by Molmil](/molmil-images/mine/8c4m) | CdaA-Adenosine complex | Descriptor: | ADENOSINE, CHLORIDE ION, Diadenylate cyclase | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2023-01-04 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor. Microlife, 4, 2023
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1BGS
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![BU of 1bgs by Molmil](/molmil-images/mine/1bgs) | RECOGNITION BETWEEN A BACTERIAL RIBONUCLEASE, BARNASE, AND ITS NATURAL INHIBITOR, BARSTAR | Descriptor: | BARNASE, BARSTAR | Authors: | Guillet, V, Lapthorn, A, Mauguen, Y. | Deposit date: | 1993-11-02 | Release date: | 1994-04-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar. Structure, 1, 1993
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8CBT
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![BU of 8cbt by Molmil](/molmil-images/mine/8cbt) | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT872 | Descriptor: | (2~{S})-2-[3-cyclopropyl-2-(3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | Deposit date: | 2023-01-25 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
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