7BNR
 
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7BNK
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3EHU
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3H6W
 | | Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution | | Descriptor: | (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ... | | Authors: | Hald, H, Gajhede, M, Kastrup, J.S. | | Deposit date: | 2009-04-24 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
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1WXX
 | | Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8 | | Descriptor: | PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280 | | Authors: | Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-02-02 | | Release date: | 2005-08-02 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
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1WXW
 | | Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8 | | Descriptor: | HEXANE-1,6-DIOL, hypothetical protein TTHA1280 | | Authors: | Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-02-02 | | Release date: | 2005-08-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
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6XJF
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6XRE
 | | Structure of the p53/RNA polymerase II assembly | | Descriptor: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | | Authors: | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | | Deposit date: | 2020-07-12 | | Release date: | 2021-03-24 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the p53/RNA polymerase II assembly.
Commun Biol, 4, 2021
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6XEO
 | | Structure of Mfd bound to dsDNA | | Descriptor: | DNA (5'-D(P*AP*GP*GP*AP*TP*AP*CP*TP*TP*AP*CP*AP*GP*CP*CP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*GP*GP*CP*TP*GP*TP*AP*AP*GP*TP*AP*TP*CP*CP*T)-3'), Transcription-repair-coupling factor | | Authors: | Brugger, C, Deaconescu, A. | | Deposit date: | 2020-06-12 | | Release date: | 2020-08-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd.
Nat Commun, 11, 2020
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6XKI
 | | Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog | | Descriptor: | (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | | Authors: | Liang, J, Naineni, S.K, Pelletier, J, Nagar, B. | | Deposit date: | 2020-06-26 | | Release date: | 2021-01-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Cell Chem Biol, 28, 2021
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1YQT
 | | RNase-L Inhibitor | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNase l inhibitor | | Authors: | Karcher, A, Buttner, K, Martens, B, Jansen, R.P, Hopfner, K.P. | | Deposit date: | 2005-02-02 | | Release date: | 2005-04-19 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray structure of RLI, an essential twin cassette ABC ATPase involved in ribosome biogenesis and HIV capsid assembly.
Structure, 13, 2005
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6Z9T
 | | Transcription termination intermediate complex 5 | | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Said, N, Hilal, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-06-04 | | Release date: | 2020-11-04 | | Last modified: | 2021-02-03 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
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6Z9P
 | | Transcription termination intermediate complex 1 | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Said, N, Hilal, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-06-04 | | Release date: | 2020-11-04 | | Last modified: | 2021-02-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
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6Z9Q
 | | Transcription termination intermediate complex 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Said, N, Hilal, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-06-04 | | Release date: | 2020-11-04 | | Last modified: | 2021-02-03 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
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2AL5
 | | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam | | Descriptor: | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2 | | Authors: | Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. | | Deposit date: | 2005-08-04 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
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1EJP
 | | SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN | | Descriptor: | SYNDECAN-4 | | Authors: | Lee, D, Oh, E.S, Woods, A, Couchman, J.R, Lee, W. | | Deposit date: | 2000-03-03 | | Release date: | 2001-09-19 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the dimeric cytoplasmic domain of syndecan-4.
Biochemistry, 40, 2001
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2MDQ
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1FJE
 | | SOLUTION STRUCTURE OF NUCLEOLIN RBD12 IN COMPLEX WITH SNRE RNA | | Descriptor: | NUCLEOLIN RBD12, SNRE RNA | | Authors: | Allain, F.H.T, Bouvet, P, Dieckmann, T, Feigon, J. | | Deposit date: | 2000-08-08 | | Release date: | 2001-01-03 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.
EMBO J., 19, 2000
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1GID
 | | CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING | | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN | | Authors: | Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A. | | Deposit date: | 1996-08-22 | | Release date: | 1996-12-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
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1EQC
 | | EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS IN COMPLEX WITH CASTANOSPERMINE AT 1.85 A | | Descriptor: | CASTANOSPERMINE, EXO-(B)-(1,3)-GLUCANASE | | Authors: | Cutfield, S.M, Davies, G.J, Murshudov, G, Anderson, B.F, Moody, P.C.E, Sullivan, P.A, Cutfield, J.F. | | Deposit date: | 2000-04-03 | | Release date: | 2000-10-03 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases.
J.Mol.Biol., 294, 1999
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2OWO
 | | Last Stop on the Road to Repair: Structure of E.coli DNA Ligase Bound to Nicked DNA-Adenylate | | Descriptor: | 26-MER, 5'-D(*AP*CP*AP*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*G)-3', ... | | Authors: | Shuman, S, Nandakumar, J, Nair, P.A. | | Deposit date: | 2007-02-16 | | Release date: | 2007-05-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Last Stop on the Road to Repair: Structure of E. coli DNA Ligase Bound to Nicked DNA-Adenylate.
Mol.Cell, 26, 2007
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2OSH
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2PCO
 | | Spatial Structure and Membrane Permeabilization for Latarcin-1, a Spider Antimicrobial Peptide | | Descriptor: | Latarcin-1 | | Authors: | Dubovskii, P.V, Volynsky, P.E, Polyansky, A.A, Chupin, V.V, Efremov, R.G, Arseniev, A.S. | | Deposit date: | 2007-03-30 | | Release date: | 2008-03-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity.
Biochemistry, 47, 2008
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7ME1
 | | YfeA oligomer crystal 1, form 1 | | Descriptor: | FE (III) ION, MANGANESE (II) ION, Periplasmic chelated iron-binding protein YfeA, ... | | Authors: | Radka, C.D, Aller, S.G. | | Deposit date: | 2021-04-06 | | Release date: | 2021-08-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site.
Acta Crystallogr.,Sect.F, 77, 2021
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4MH8
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