Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5LSQ
DownloadVisualize
BU of 5lsq by Molmil
Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Ethylene Forming Enzyme, ...
Authors:Zhang, Z, McDonough, M.A, Schofield, C.J.
Deposit date:2016-09-05
Release date:2017-04-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2Y6F
DownloadVisualize
BU of 2y6f by Molmil
Isopenicillin N synthase with AC-D-S-methyl-3R-methylcysteine
Descriptor: (2S)-2-AMINO-6-[[(2R)-1-[[(2S)-1-HYDROXY-3-METHYLSULFANYL-1-OXO-BUTAN-2-YL]AMINO]-1-OXO-3-SULFANYL-PROPAN-2-YL]AMINO]-6-OXO-HEXANOIC ACID, FE (III) ION, ISOPENICILLIN N SYNTHASE, ...
Authors:Rutledge, P.J, Clifton, I.J, Ge, W.
Deposit date:2011-01-21
Release date:2011-08-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Isopenicillin N Synthase Binds Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D-Thia-Allo-Isoleucine Through Both Sulfur Atoms.
Chembiochem, 12, 2011
2Y60
DownloadVisualize
BU of 2y60 by Molmil
Isopenicillin N synthase with AC-D-methionine
Descriptor: FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ...
Authors:Rutledge, P.J, Clifton, I.J, Ge, W.
Deposit date:2011-01-19
Release date:2012-02-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Crystal Structure of Isopenicillin N Synthase with Delta((L)-Alpha-Aminoadipoyl)-(L)-Cysteinyl-(D)-Methionine Reveals Thioether Coordination to Iron.
Arch.Biochem.Biophys., 516, 2011
6VP4
DownloadVisualize
BU of 6vp4 by Molmil
Ethylene forming enzyme (EFE) in complex with Fe(II), L-arginine, and 2OG
Descriptor: 2-OXOGLUTARIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ...
Authors:Davis, K.M, Copeland, R.A, Boal, A.K.
Deposit date:2020-02-01
Release date:2021-02-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme.
J.Am.Chem.Soc., 143, 2021
5LUN
DownloadVisualize
BU of 5lun by Molmil
Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - P1 ultra-high resolution crystal form in complex with iron, N-oxalylglycine and arginine
Descriptor: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, FE (III) ION, ...
Authors:McDonough, M.A, Zhang, Z, Schofield, C.J.
Deposit date:2016-09-09
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3ON7
DownloadVisualize
BU of 3on7 by Molmil
Crystal structure of a Putative oxygenase (SO_2589) from Shewanella oneidensis at 2.20 A resolution
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-08-27
Release date:2010-09-15
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a Putative oxygenase (SO_2589) from Shewanella oneidensis at 2.20 A resolution
To be published
5GJ9
DownloadVisualize
BU of 5gj9 by Molmil
Crystal structure of Arabidopsis thaliana ACO2 in complex with POA
Descriptor: 1-aminocyclopropane-1-carboxylate oxidase 2, PYRAZINE-2-CARBOXYLIC ACID, ZINC ION
Authors:Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W.
Deposit date:2016-06-28
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
3OOX
DownloadVisualize
BU of 3oox by Molmil
Crystal structure of a putative 2OG-Fe(II) oxygenase family protein (CC_0200) from CAULOBACTER CRESCENTUS at 1.44 A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, putative 2OG-Fe(II) oxygenase family protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-08-31
Release date:2010-12-01
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Crystal structure of a putative 2OG-Fe(II) oxygenase family protein (CC_0200) from CAULOBACTER CRESCENTUS at 1.44 A resolution
To be published
6XJJ
DownloadVisualize
BU of 6xjj by Molmil
Structure of non-heme iron enzyme TropC: Radical tropolone biosynthesis
Descriptor: 2-oxoglutarate-dependent dioxygenase tropC, ACETATE ION, FE (III) ION, ...
Authors:Mallik, L, Doyon, T.J, Narayan, A.R.H, Koutmos, M.
Deposit date:2020-06-24
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Radical Tropolone Biosynthesis
Chemrxiv, 2020
7P3L
DownloadVisualize
BU of 7p3l by Molmil
Isopenicillin N synthase in complex with Fe and the substrate analogue AadCyshomoCys
Descriptor: 2-AMINOHEXANEDIOIC ACID, CYSTEINE, D-homocysteine, ...
Authors:Rabe, P, Clifton, I, Schofield, C.J.
Deposit date:2021-07-08
Release date:2022-07-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Isopenicillin N synthase in complex with Fe and the substrate analogue AadCyshomoCys
To Be Published
6Y0O
DownloadVisualize
BU of 6y0o by Molmil
isopenicillin N synthase in complex with ACV and Fe under anaerobic environment using FT-SSX methods
Descriptor: Anaerobic Fixed Target Structure of Isopenicillin N synthase in complex with Fe and ACV, FE (III) ION, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:Rabe, P, Beale, J.H, Lang, P.A, Dirr, A.S, Leissing, T.M, Butryn, A, Aller, P, Kamps, J.J.A.G, Axford, D, McDonough, M.A, Orville, A.M, Owen, R, Schofield, C.J.
Deposit date:2020-02-10
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anaerobic fixed-target serial crystallography.
Iucrj, 7, 2020
7POY
DownloadVisualize
BU of 7poy by Molmil
Spin labeled IPNS S55C variant in complex with Fe, ACV and NO
Descriptor: FE (III) ION, Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:Rabe, P, Clifton, I, Walla, C, Schofield, C.J.
Deposit date:2021-09-10
Release date:2022-07-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase.
J.Biol.Chem., 298, 2022
7PSW
DownloadVisualize
BU of 7psw by Molmil
Spin labeled IPNS S55C variant in complex with Fe and ACV under anaerobic conditions
Descriptor: FE (III) ION, GLYCEROL, Isopenicillin N synthase, ...
Authors:Rabe, P, Clifton, I, Walla, C, Schofield, C.J.
Deposit date:2021-09-24
Release date:2022-07-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase.
J.Biol.Chem., 298, 2022
2BRT
DownloadVisualize
BU of 2brt by Molmil
ANTHOCYANIDIN SYNTHASE FROM ARABIDOPSIS THALIANA COMPLEXED with naringenin
Descriptor: 2-OXOGLUTARIC ACID, FE (II) ION, LEUCOANTHOCYANIDIN DIOXYGENASE, ...
Authors:Turnbull, J.J, Clifton, I.J, Welford, R.W.D, Schofield, C.J.
Deposit date:2005-05-11
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mechanistic Studies on Anthocyanidin Synthase Catalysed Oxidation of Flavanone Substrates: The Effect of C-2 Stereochemistry on Product Selectivity and Mechanism
Org.Biomol.Chem., 3, 2005
6Y0P
DownloadVisualize
BU of 6y0p by Molmil
isopenicillin N synthase in complex with IPN and Fe using FT-SSX methods
Descriptor: FE (III) ION, ISOPENICILLIN N, Isopenicillin N synthase, ...
Authors:Rabe, P, Beale, J.H, Lang, P.A, Dirr, A.S, Leissing, T.M, Butryn, A, Aller, P, Kamps, J.J.A.G, Axford, D, McDonough, M.A, Orville, A.M, Owen, R, Schofield, C.J.
Deposit date:2020-02-10
Release date:2021-02-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis.
Sci Adv, 7, 2021
2BJS
DownloadVisualize
BU of 2bjs by Molmil
Isopenicillin N synthase C-terminal truncation mutant
Descriptor: FE (III) ION, ISOPENICILLIN N SYNTHETASE, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:McNeill, L.A, Sami, M, Clifton, I.J, Burzlaff, N.I.
Deposit date:2005-02-07
Release date:2006-03-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.
Chemistry, 23, 2017
3ZKY
DownloadVisualize
BU of 3zky by Molmil
Isopenicillin N synthase with substrate analogue AhCmC
Descriptor: FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ...
Authors:Daruzzaman, A, Clifton, I.J, Rutledge, P.J.
Deposit date:2013-01-25
Release date:2013-03-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Homocysteinyl-D-Xaa Characterised by Protein Crystallography.
Chembiochem, 14, 2013
5O9W
DownloadVisualize
BU of 5o9w by Molmil
Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum in complex with 2-oxoglutarate
Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Kluza, A, Niedzialkowska, E, Kurpiewska, K, Porebski, P.J, Borowski, T.
Deposit date:2017-06-20
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway.
J. Struct. Biol., 202, 2018
2BU9
DownloadVisualize
BU of 2bu9 by Molmil
Isopenicillin N synthase complexed with L-aminoadipoyl-L-cysteinyl-L- hexafluorovaline
Descriptor: DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-L-3,3,3,3',3',3'-HEXAFLUOROVALINE, FE (III) ION, ISOPENICILLIN N SYNTHETASE, ...
Authors:Howard-Jones, A.R, Rutledge, P.J, Clifton, I.J, Adlington, R.M, Baldwin, J.E.
Deposit date:2005-06-09
Release date:2005-09-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Unique Binding of a Non-Natural L,L,L-Substrate by Isopenicillin N Synthase
Biochem.Biophys.Res.Commun., 336, 2005
3ZKU
DownloadVisualize
BU of 3zku by Molmil
Isopenicillin N synthase with substrate analogue AhCV
Descriptor: FE (III) ION, ISOPENICILLIN N SYNTHASE, N-[(5S)-5-amino-5-carboxypentanoyl]-L-homocysteyl-D-valine
Authors:Daruzzaman, A, Clifton, I.J, Rutledge, P.J.
Deposit date:2013-01-24
Release date:2013-02-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Homocysteinyl-D-Xaa Characterised by Protein Crystallography.
Chembiochem, 14, 2013
3ZOI
DownloadVisualize
BU of 3zoi by Molmil
ISOPENICILLIN N SYNTHASE WITH AC-O-METHYL-D-THREONINE
Descriptor: DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-O-METHYL-D-THREONINE, FE (III) ION, GLYCEROL, ...
Authors:Rutledge, P.J, Clifton, I.J, Ge, W.
Deposit date:2013-02-21
Release date:2013-06-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of an Isopenicillin N Synthase Complex with an Ethereal Substrate Analogue Reveals Water in the Oxygen Binding Site.
FEBS Lett., 587, 2013
5O7Y
DownloadVisualize
BU of 5o7y by Molmil
Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum in complex with succinate
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NICKEL (II) ION, ...
Authors:Kluza, A, Niedzialkowska, E, Kurpiewska, K, Porebski, P.J, Borowski, T.
Deposit date:2017-06-10
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway.
J. Struct. Biol., 202, 2018
5MOF
DownloadVisualize
BU of 5mof by Molmil
Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form in complex with manganese and 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, CHLORIDE ION, ...
Authors:McDonough, M.A, Zhang, Z, Schofield, C.J.
Deposit date:2016-12-14
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1IPS
DownloadVisualize
BU of 1ips by Molmil
ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX)
Descriptor: ISOPENICILLIN N SYNTHASE, MANGANESE (II) ION
Authors:Roach, P.L, Clifton, I.J, Fulop, V, Harlos, K, Barton, G.J, Hajdu, J, Andersson, I, Schofield, C.J, Baldwin, J.E.
Deposit date:1997-03-21
Release date:1998-03-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
Nature, 375, 1995
8A4G
DownloadVisualize
BU of 8a4g by Molmil
IPNS H270E variant in complex with Cd and ACV
Descriptor: CADMIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2022-06-11
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:IPNS H270E variant in complex with Cd and ACV
To Be Published

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon