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9ASJ
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BU of 9asj by Molmil
Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
Descriptor: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-26
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
8W0A
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BU of 8w0a by Molmil
Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-13
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
9FMD
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BU of 9fmd by Molmil
Integrative model of the human post-catalytic spliceosome (P-complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Rothe, P, Plaschka, C, Vorlaender, M.K.
Deposit date:2024-06-05
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 2024
8WTK
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BU of 8wtk by Molmil
Crystal structure of Cas3-DExD+MG
Descriptor: CRISPR-associated helicase Cas3, MAGNESIUM ION
Authors:Mo, X.
Deposit date:2023-10-18
Release date:2024-07-24
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Structural insight into dynamic characteristic of the polymerized forms of kinetoplastid membrane protein-11
To be published
8I0V
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BU of 8i0v by Molmil
The cryo-EM structure of human post-Bact complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0P
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BU of 8i0p by Molmil
The cryo-EM structure of human pre-Bact complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0W
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BU of 8i0w by Molmil
The cryo-EM structure of human C complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0R
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BU of 8i0r by Molmil
The cryo-EM structure of human Bact-I complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0U
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BU of 8i0u by Molmil
The cryo-EM structure of human Bact-IV complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0T
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BU of 8i0t by Molmil
The cryo-EM structure of human Bact-III complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0S
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BU of 8i0s by Molmil
The cryo-EM structure of human Bact-II complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2023-01-11
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8RO1
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BU of 8ro1 by Molmil
Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'')
Descriptor: CWF19-like protein 1 homolog, CWF19-like protein 2 homolog, Cell division cycle 5-like protein, ...
Authors:Vorlaender, M.K, Rothe, P, Plaschka, C.
Deposit date:2024-01-11
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
8RO0
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BU of 8ro0 by Molmil
Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS')
Descriptor: Cell division cycle 5-like protein, Coiled-coil domain-containing protein 12, GCF C-terminal domain-containing protein, ...
Authors:Vorlaender, M.K, Rothe, P, Plaschka, C.
Deposit date:2024-01-11
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
9BP9
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BU of 9bp9 by Molmil
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form
Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-05-07
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
9BPA
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BU of 9bpa by Molmil
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form
Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-05-07
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024

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PDB entries from 2024-09-11

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