1XU1
 
 | | The crystal structure of APRIL bound to TACI | | Descriptor: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B | | Authors: | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | | Deposit date: | 2004-10-25 | | Release date: | 2004-11-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
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1XU2
 | | The crystal structure of APRIL bound to BCMA | | Descriptor: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17 | | Authors: | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | | Deposit date: | 2004-10-25 | | Release date: | 2004-11-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
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1XT9
 | | Crystal Structure of Den1 in complex with Nedd8 | | Descriptor: | Neddylin, Sentrin-specific protease 8 | | Authors: | Reverter, D, Wu, K, Erdene, T.G, Pan, Z.Q, Wilkinson, K.D, Lima, C.D. | | Deposit date: | 2004-10-21 | | Release date: | 2004-12-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1.
J.Mol.Biol., 345, 2005
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1XUW
 | | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs | | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3') | | Authors: | Pattanayek, R, Sethaphong, L, Pan, C, Prhavc, M, Prakash, T.P, Manoharan, M, Egli, M. | | Deposit date: | 2004-10-26 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126, 2004
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1YU9
 | | GppNHp-Bound Rab4A | | Descriptor: | GTP-binding protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-13 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YZK
 | | GppNHp bound Rab11 GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-11A | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YZU
 | | GppNHp-Bound Rab21 GTPase at 2.50 A Resolution | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-21 | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0A
 | | GDP-Bound Rab2A GTPase | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-2A | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YZN
 | | GppNHp-Bound Ypt1p GTPase | | Descriptor: | GTP-binding protein YPT1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0J
 | | Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GLYCEROL, ... | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z5F
 | | Solution Structure of the Cytotoxic RC-RNase 3 with a Pyroglutamate Residue at the N-terminus | | Descriptor: | RC-RNase 3 | | Authors: | Lou, Y.C, Huang, Y.C, Pan, Y.R, Chen, C, Liao, Y.D. | | Deposit date: | 2005-03-18 | | Release date: | 2006-02-28 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Roles of N-terminal pyroglutamate in maintaining structural integrity and pKa values of catalytic histidine residues in bullfrog ribonuclease 3
J.Mol.Biol., 355, 2006
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1Z08
 | | GppNHp-Bound Rab21 Q53G mutant GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-21 | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0K
 | | Structure of GTP-Bound Rab4Q67L GTPase in complex with the central Rab binding domain of Rabenosyn-5 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GTP-binding protein, ... | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z07
 | | GppNHp-Bound Rab5c G55Q mutant GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5C | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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6NO9
 | | PIM1 in complex with Cpd16 (5-amino-N-(5-((4R,5R)-4-amino-5-fluoroazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide) | | Descriptor: | 5-amino-N-{5-[(4R,5R)-4-amino-5-fluoroazepan-1-yl]-1-methyl-1H-pyrazol-4-yl}-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxamide, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Murray, J.M, Noland, C. | | Deposit date: | 2019-01-15 | | Release date: | 2019-02-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.712 Å) | | Cite: | Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
J. Med. Chem., 62, 2019
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1YZL
 | | GppNHp-Bound Rab9 GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-9A | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0I
 | | GDP-Bound Rab21 GTPase | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-21 | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0F
 | | GDP-Bound Rab14 GTPase | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAB14, ... | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z2A
 | | GDP-Bound Rab23 GTPase crystallized in P2(1)2(1)2(1) space group | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-23 | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-07 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YZQ
 | | GppNHp-Bound Rab6 GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, small GTP binding protein RAB6 isoform | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z7Q
 | | Crystal structure of the 20s proteasome from yeast in complex with the proteasome activator PA26 from Trypanosome brucei at 3.2 angstroms resolution | | Descriptor: | Potential proteasome component C5, Proteasome component C1, Proteasome component C11, ... | | Authors: | Forster, A, Whitby, F.G, Hill, C.P. | | Deposit date: | 2005-03-26 | | Release date: | 2005-08-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
Mol.Cell, 18, 2005
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1YZM
 | | Structure of Rabenosyn (458-503), Rab4 binding domain | | Descriptor: | FYVE-finger-containing Rab5 effector protein rabenosyn-5 | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-28 | | Release date: | 2005-07-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z06
 | | GppNHp-Bound Rab33 GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-33B | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0D
 | | GDP-Bound Rab5c GTPase | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-03-01 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YVD
 | | GppNHp-Bound Rab22 GTPase | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-22A | | Authors: | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | Deposit date: | 2005-02-15 | | Release date: | 2005-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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