8JL9
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![BU of 8jl9 by Molmil](/molmil-images/mine/8jl9) | Cryo-EM structure of the human nucleosome with scFv | Descriptor: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-06-02 | Release date: | 2023-10-04 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLB
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![BU of 8jlb by Molmil](/molmil-images/mine/8jlb) | Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-06-02 | Release date: | 2023-10-04 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLD
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![BU of 8jld by Molmil](/molmil-images/mine/8jld) | Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-06-02 | Release date: | 2023-10-04 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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4YGX
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![BU of 4ygx by Molmil](/molmil-images/mine/4ygx) | |
2WHO
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![BU of 2who by Molmil](/molmil-images/mine/2who) | |
1YV2
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![BU of 1yv2 by Molmil](/molmil-images/mine/1yv2) | Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a | Descriptor: | GLYCEROL, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-14 | Release date: | 2005-03-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
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8JLA
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![BU of 8jla by Molmil](/molmil-images/mine/8jla) | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | Descriptor: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-06-02 | Release date: | 2023-10-04 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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2EC0
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![BU of 2ec0 by Molmil](/molmil-images/mine/2ec0) | RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP | Descriptor: | 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-02-09 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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2A69
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![BU of 2a69 by Molmil](/molmil-images/mine/2a69) | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-02 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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3P8B
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![BU of 3p8b by Molmil](/molmil-images/mine/3p8b) | |
6IRV
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![BU of 6irv by Molmil](/molmil-images/mine/6irv) | |
6IRW
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![BU of 6irw by Molmil](/molmil-images/mine/6irw) | Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH | Descriptor: | Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-14 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
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6XKB
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![BU of 6xkb by Molmil](/molmil-images/mine/6xkb) | Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD | Descriptor: | S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION | Authors: | Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-26 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4. Febs Lett., 596, 2022
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2A68
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![BU of 2a68 by Molmil](/molmil-images/mine/2a68) | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-01 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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6IRY
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![BU of 6iry by Molmil](/molmil-images/mine/6iry) | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH | Descriptor: | 1,2-ETHANEDIOL, PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-14 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
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6IRX
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![BU of 6irx by Molmil](/molmil-images/mine/6irx) | |
3AYH
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![BU of 3ayh by Molmil](/molmil-images/mine/3ayh) | |
1YVZ
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![BU of 1yvz by Molmil](/molmil-images/mine/1yvz) | Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | Descriptor: | 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-16 | Release date: | 2005-03-22 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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1YVX
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![BU of 1yvx by Molmil](/molmil-images/mine/1yvx) | Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | Descriptor: | 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-16 | Release date: | 2005-03-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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7JV7
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![BU of 7jv7 by Molmil](/molmil-images/mine/7jv7) | Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex | Descriptor: | CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ... | Authors: | Xie, Y, Ren, Y. | Deposit date: | 2020-08-20 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.850553 Å) | Cite: | Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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1H38
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![BU of 1h38 by Molmil](/molmil-images/mine/1h38) | Structure of a T7 RNA polymerase elongation complex at 2.9A resolution | Descriptor: | 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... | Authors: | Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. | Deposit date: | 2002-08-24 | Release date: | 2002-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
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2XI5
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![BU of 2xi5 by Molmil](/molmil-images/mine/2xi5) | N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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2XI7
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![BU of 2xi7 by Molmil](/molmil-images/mine/2xi7) | N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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1HQM
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![BU of 1hqm by Molmil](/molmil-images/mine/1hqm) | CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K. | Deposit date: | 2000-12-18 | Release date: | 2001-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Proc.Natl.Acad.Sci.USA, 98, 2001
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1NB7
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![BU of 1nb7 by Molmil](/molmil-images/mine/1nb7) | HC-J4 RNA polymerase complexed with short RNA template strand | Descriptor: | 5'-R(*UP*UP*UP*U)-3', MANGANESE (II) ION, polyprotein | Authors: | O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. | Deposit date: | 2002-12-02 | Release date: | 2003-03-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
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