3I2U
| Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
|
|
3I2S
| Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
|
|
3I2R
| Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
|
|
3CQS
| A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases | Descriptor: | 13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 19-mer ribozyme strand, ... | Authors: | Torelli, A.T, Spitale, R.C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2008-04-03 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme Biochem.Biophys.Res.Commun., 371, 2008
|
|
6ABZ
| Crystal Structure of HEWL in deionized water | Descriptor: | CHLORIDE ION, Lysozyme C, S-1,2-PROPANEDIOL, ... | Authors: | Seyedarabi, A, Seraj, Z. | Deposit date: | 2018-07-24 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The role of Cinnamaldehyde and Phenyl ethyl alcohol as two types of precipitants affecting protein hydration levels. Int.J.Biol.Macromol., 146, 2019
|
|
6AGR
| Structure of HEWL co-crystallised with phenylethyl alcohol | Descriptor: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, ACETATE ION, ... | Authors: | Seyedarabi, A, Seraj, Z. | Deposit date: | 2018-08-13 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | The role of Cinnamaldehyde and Phenyl ethyl alcohol as two types of precipitants affecting protein hydration levels. Int.J.Biol.Macromol., 146, 2019
|
|
4TVV
| Crystal structure of LppA from Legionella pneumophila | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Weber, S, Stirnimann, C, Wieser, M, Meier, R, Engelhardt, S, Li, X, Capitani, G, Kammerer, R, Hilbi, H. | Deposit date: | 2014-06-28 | Release date: | 2014-11-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A Type IV Translocated Legionella Cysteine Phytase Counteracts Intracellular Growth Restriction by Phytate. J.Biol.Chem., 289, 2014
|
|
4WAS
| STRUCTURE OF THE ETR1P/NADP/CROTONYL-COA COMPLEX | Descriptor: | CROTONYL COENZYME A, Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, ... | Authors: | Quade, N, Voegeli, B, Rosenthal, R, Capitani, G, Erb, T.J. | Deposit date: | 2014-08-31 | Release date: | 2015-03-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The use of ene adducts to study and engineer enoyl-thioester reductases. Nat.Chem.Biol., 11, 2015
|
|
6YJX
| Structure of Hen egg-white lysozyme crystallized with PAS polypeptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Schiefner, A, Skerra, A. | Deposit date: | 2020-04-05 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization. Acta Crystallogr.,Sect.F, 76, 2020
|
|
6YJW
| Structure of Fragaria ananassa O-methyltransferase crystallized with PAS polypeptide | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, O-methyltransferase, ... | Authors: | Schiefner, A, Skerra, A. | Deposit date: | 2020-04-05 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization. Acta Crystallogr.,Sect.F, 76, 2020
|
|
3MAU
| Crystal structure of StSPL in complex with phosphoethanolamine | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, sphingosine-1-phosphate lyase, ... | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-24 | Release date: | 2010-08-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
|
|
3MAD
| |
3MBB
| Crystal structure of StSPL - apo form, after treatment with semicarbazide | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ... | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-25 | Release date: | 2010-08-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
|
|
3MC6
| Crystal structure of ScDPL1 | Descriptor: | PHOSPHATE ION, Sphingosine-1-phosphate lyase | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-27 | Release date: | 2010-08-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
|
|
2BKK
| Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ... | Authors: | Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G. | Deposit date: | 2005-02-16 | Release date: | 2005-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein Structure, 13, 2005
|
|
7DMM
| |
1PS5
| STRUCTURE OF THE MONOCLINIC C2 FORM OF HEN EGG-WHITE LYSOZYME AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | Lysozyme C, SULFATE ION | Authors: | Majeed, S, Ofek, G, Belachew, A, Huang, C, Zhou, T, Kwong, P.D. | Deposit date: | 2003-06-20 | Release date: | 2003-09-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enhancing Protein Crystallization through Precipitant Synergy Structure, 11, 2003
|
|
1T2Q
| The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ... | Authors: | Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E. | Deposit date: | 2004-04-22 | Release date: | 2005-06-07 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen To be Published
|
|
4OVA
| |
7B0W
| Crystal structure of the E. coli type 1 pilus assembly inhibitor FimI bound to FimC | Descriptor: | 1,2-ETHANEDIOL, Chaperone protein FimC, FORMIC ACID, ... | Authors: | Scharer, M.A, Zigova, Z, Giese, C, Puorger, C, Ignatov, O, Capitani, G, Glockshuber, R. | Deposit date: | 2020-11-23 | Release date: | 2021-12-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Comprehensive kinetic characterization of bacterial pilus rod assembly and assembly termination To Be Published
|
|
7B0X
| Crystal structure of the ternary complex of the E. coli type 1 pilus proteins FimC, FimI and the N-terminal domain of FimD | Descriptor: | 1,2-ETHANEDIOL, Chaperone protein FimC, Fimbrin-like protein FimI, ... | Authors: | Scharer, M.A, Zigova, Z, Giese, C, Puorger, C, Ignatov, O, Capitani, G, Glockshuber, R. | Deposit date: | 2020-11-23 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Comprehensive kinetic characterization of bacterial pilus rod assembly and assembly termination To Be Published
|
|
4CG9
| Human choline kinase a1 in complex with compound 12 | Descriptor: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[(4-phenylphenyl)methyl]pyridin-1-ium-4-amine | Authors: | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | Deposit date: | 2013-11-21 | Release date: | 2014-01-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
|
|
4CGA
| Human choline kinase a1 in complex with compound 5 | Descriptor: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[[4-(2-phenylethyl)phenyl]methyl]pyridin-1-ium-4-amine | Authors: | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | Deposit date: | 2013-11-21 | Release date: | 2014-01-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
|
|
6AGN
| Structure of HEWL co-crystallised with Cinnamaldehyde | Descriptor: | (2E)-3-phenylprop-2-enal, (2Z)-3-phenylprop-2-enal, 1,2-ETHANEDIOL, ... | Authors: | Seyedarabi, A, Seraj, Z. | Deposit date: | 2018-08-13 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | The role of Cinnamaldehyde and Phenyl ethyl alcohol as two types of precipitants affecting protein hydration levels. Int.J.Biol.Macromol., 146, 2019
|
|
8WSV
| |