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5GME
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BU of 5gme by Molmil
Crystal structure of Sulfolobus solfataricus Diphosphomevalonate decarboxylase in complex with ADP
Descriptor: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Unno, H, Hemmi, H, Hattori, A.
Deposit date:2016-07-13
Release date:2016-12-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase
J. Biol. Chem., 292, 2017
5V2L
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BU of 5v2l by Molmil
Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Mevalonate diphosphate decarboxylase, PHOSPHATE ION
Authors:Stauffacher, C.V, Chen, C.-L.
Deposit date:2017-03-05
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017
1UEK
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BU of 1uek by Molmil
Crystal structure of 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase
Descriptor: 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase
Authors:Wada, T, Kuramitsu, S, Yokoyama, S, Tame, J.R.H, Park, S.Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-17
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis.
J.Biol.Chem., 278, 2003
1PIE
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BU of 1pie by Molmil
Crystal Structure of Lactococcus lactis Galactokinase Complexed with Galactose
Descriptor: Galactokinase, PHOSPHATE ION, alpha-D-galactopyranose
Authors:Thoden, J.B, Holden, H.M.
Deposit date:2003-05-30
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Structure of Galactokinase
J.Biol.Chem., 278, 2003
4Z7C
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BU of 4z7c by Molmil
Diphosphomevalonate decarboxylase from the Sulfolobus solfataricus, space group h32
Descriptor: Diphosphomevalonate decarboxylase, GLYCEROL, PHOSPHATE ION, ...
Authors:Unno, H, Hattori, A, Hemmi, H.
Deposit date:2015-04-07
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus
J.Bacteriol., 197, 2015
3V5R
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BU of 3v5r by Molmil
Crystal structure of the unliganded form of Gal3p
Descriptor: Protein GAL3, SULFATE ION
Authors:Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L.
Deposit date:2011-12-16
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
1S4E
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BU of 1s4e by Molmil
Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ...
Authors:Hartley, A, Glynn, S.E, Barynin, V, Baker, P.J, Sedelnikova, S.E, Verhees, C, de Geus, D, van der Oost, J, Timson, D.J, Reece, R.J, Rice, D.W.
Deposit date:2004-01-16
Release date:2004-04-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
3V2U
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BU of 3v2u by Molmil
Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Galactose/lactose metabolism regulatory protein GAL80, ...
Authors:Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L.
Deposit date:2011-12-12
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
4Z7Y
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BU of 4z7y by Molmil
diphosphomevalonate decarboxylase from the Sulfolobus solfataricus, space group P21
Descriptor: Diphosphomevalonate decarboxylase, SULFATE ION
Authors:Hattori, A, Unno, H, Hemmi, H.
Deposit date:2015-04-08
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus
J.Bacteriol., 197, 2015
1OJ4
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BU of 1oj4 by Molmil
Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Descriptor: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ...
Authors:Miallau, L, Alphey, M.S, Hunter, W.N.
Deposit date:2003-06-30
Release date:2003-07-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
2HFU
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BU of 2hfu by Molmil
Crystal structure of L. major mevalonate kinase in complex with R-mevalonate
Descriptor: (R)-MEVALONATE, Mevalonate kinase, putative
Authors:Sgraja, T, Hunter, W.N.
Deposit date:2006-06-26
Release date:2007-04-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.
Bmc Struct.Biol., 7, 2007
2HFS
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BU of 2hfs by Molmil
Crystal structure of L. major mevalonate kinase
Descriptor: Mevalonate kinase, putative
Authors:Sgraja, T, Hunter, W.N.
Deposit date:2006-06-26
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.
Bmc Struct.Biol., 7, 2007
5V2M
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BU of 5v2m by Molmil
Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis
Descriptor: Mevalonate diphosphate decarboxylase, SULFATE ION
Authors:Stauffacher, C.V, Chen, C.-L.
Deposit date:2017-03-05
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017
2A2C
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BU of 2a2c by Molmil
x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate
Descriptor: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Thoden, J.B, Holden, H.M.
Deposit date:2005-06-22
Release date:2005-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The molecular architecture of human N-acetylgalactosamine kinase.
J.Biol.Chem., 280, 2005
4ED4
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BU of 4ed4 by Molmil
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP
Descriptor: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-03-26
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EMD
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BU of 4emd by Molmil
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4
Descriptor: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-04-11
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
6MDE
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BU of 6mde by Molmil
Mevalonate kinase from Methanosarcina mazei with mevalonate bound
Descriptor: (R)-MEVALONATE, GLYCEROL, Mevalonate kinase, ...
Authors:Miller, B.R, Kung, Y.
Deposit date:2018-09-04
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into substrate and product binding in an archaeal mevalonate kinase.
PLoS ONE, 13, 2018
6MDF
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BU of 6mdf by Molmil
Mevalonate kinase from Methanosarcina mazei with 5-phosphomevalonate bound
Descriptor: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, GLYCEROL, Mevalonate kinase
Authors:Miller, B.R, Kung, Y.
Deposit date:2018-09-04
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural insight into substrate and product binding in an archaeal mevalonate kinase.
PLoS ONE, 13, 2018
6N10
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BU of 6n10 by Molmil
Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP
Descriptor: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ...
Authors:Noel, J.P, Thomas, S.T, Louie, G.V.
Deposit date:2018-11-07
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase.
Acs Chem.Biol., 14, 2019
1K47
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BU of 1k47 by Molmil
Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)
Descriptor: phosphomevalonate kinase
Authors:Romanowski, M.J, Bonanno, J.B, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-10-05
Release date:2002-05-08
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily.
Proteins, 47, 2002
6TEP
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BU of 6tep by Molmil
Crystal structure of a galactokinase from Bifidobacterium infantis in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A.
Deposit date:2019-11-12
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.
Cell Chem Biol, 27, 2020
6TEQ
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BU of 6teq by Molmil
Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-alpha-D-galactopyranose, ...
Authors:Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A.
Deposit date:2019-11-12
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.
Cell Chem Biol, 27, 2020
6TER
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BU of 6ter by Molmil
Crystal structure of a galactokinase from Bifidobacterium infantis in complex with Galactose
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A.
Deposit date:2019-11-12
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.
Cell Chem Biol, 27, 2020
1KKH
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BU of 1kkh by Molmil
Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase
Descriptor: 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase
Authors:Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C.
Deposit date:2001-12-08
Release date:2002-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
J.Biol.Chem., 277, 2002
4HAC
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BU of 4hac by Molmil
Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei
Descriptor: MAGNESIUM ION, Mevalonate kinase
Authors:Zhuang, N, Lee, K.H.
Deposit date:2012-09-26
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei.
Acta Crystallogr.,Sect.F, 68, 2012

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