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5L7M
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Murin CXCL13 solution structure
Descriptor: C-X-C motif chemokine 13
Authors:Monneau, Y.R, Lortat-Jacob, H.
Deposit date:2016-06-03
Release date:2017-06-21
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains.
Open Biol, 7, 2017
4HCS
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BU of 4hcs by Molmil
Structure of Novel subfamily CX chemokine solved by sulfur SAD
Descriptor: Uncharacterized protein
Authors:Rajasekaran, D, Fan, C, Meng, W, Pflugrath, J.W, Lolis, E.J.
Deposit date:2012-10-01
Release date:2013-10-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Structural insight into the evolution of a new chemokine family from zebrafish.
Proteins, 82, 2014
5LTL
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BU of 5ltl by Molmil
Structure of human chemokine CCL16
Descriptor: C-C motif chemokine 16, GLYCEROL, SODIUM ION
Authors:Weiergraeber, O.H, Batra-Safferling, R, Haenel, K, Willbold, D.
Deposit date:2016-09-07
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and dynamics of human chemokine CCL16
To Be Published
4HSV
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BU of 4hsv by Molmil
Crystal Structure of CXCL4L1
Descriptor: Platelet factor 4 variant
Authors:Kuo, J.H, Liu, J.S, Wu, W.G, Sue, S.C.
Deposit date:2012-10-30
Release date:2013-04-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.083 Å)
Cite:Alternative C-terminal helix orientation alters chemokine function: structure of the anti-angiogenic chemokine, CXCL4L1
J.Biol.Chem., 288, 2013
4MHE
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BU of 4mhe by Molmil
Crystal structure of CC-chemokine 18
Descriptor: ACETATE ION, C-C motif chemokine 18
Authors:Liang, W.G, Tang, W.-J.
Deposit date:2013-08-29
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
4HED
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BU of 4hed by Molmil
Zebrafish chemokine CXL1
Descriptor: Uncharacterized protein
Authors:Rajasekaran, D, Fan, C, Meng, W, Pflugrath, J.W, Lolis, E.J.
Deposit date:2012-10-03
Release date:2013-08-21
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural insight into the evolution of a new chemokine family from zebrafish.
Proteins, 82, 2014
4LMQ
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BU of 4lmq by Molmil
Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Descriptor: Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain
Authors:Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N.
Deposit date:2013-07-10
Release date:2013-08-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12.
Clin.Cancer Res., 19, 2013
4OIK
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BU of 4oik by Molmil
(Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ...
Authors:Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
Deposit date:2014-01-19
Release date:2014-05-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
1ILQ
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BU of 1ilq by Molmil
CXCR-1 N-TERMINAL PEPTIDE BOUND TO INTERLEUKIN-8 (MINIMIZED MEAN)
Descriptor: INTERLEUKIN-8 PRECURSOR, INTERLEUKIN-8 RECEPTOR A
Authors:Skelton, N.J, Quan, C, Lowman, H.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.
Structure Fold.Des., 7, 1999
5WDZ
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BU of 5wdz by Molmil
Structure of monomeric Interleukin-8 (1-66)
Descriptor: Interleukin-8
Authors:Berkamp, S, Opella, S.J, Marassi, F.M.
Deposit date:2017-07-06
Release date:2017-11-29
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structure of monomeric Interleukin-8 and its interactions with the N-terminal Binding Site-I of CXCR1 by solution NMR spectroscopy.
J. Biomol. NMR, 69, 2017
1J8I
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BU of 1j8i by Molmil
Solution Structure of Human Lymphotactin
Descriptor: Lymphotactin
Authors:Kuloglu, E.S, McCaslin, D.R, Markley, J.L, Pauza, C.D, Volkman, B.F.
Deposit date:2001-05-21
Release date:2001-10-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Monomeric solution structure of the prototypical 'C' chemokine lymphotactin.
Biochemistry, 40, 2001
1IKM
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BU of 1ikm by Molmil
NMR study of monomeric human interleukin-8 (30 structures)
Descriptor: HUMAN INTERLEUKIN-8 (MONOMERIC)
Authors:Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1995-08-03
Release date:1995-10-15
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:1H NMR solution structure of an active monomeric interleukin-8.
Biochemistry, 34, 1995
4XDX
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BU of 4xdx by Molmil
The crystal structure of soluble human interleukin 8 expressed in Pichia pastoris
Descriptor: Interleukin-8
Authors:Ostrov, D.A, Pompeu, Y.A, Jakoncic, J.J.
Deposit date:2014-12-20
Release date:2015-12-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:The crystal structure of soluble human interleukin 8 expressed in Pichia pastoris
To Be Published
1ILP
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BU of 1ilp by Molmil
CXCR-1 N-TERMINAL PEPTIDE BOUND TO INTERLEUKIN-8
Descriptor: C-X-C chemokine receptor type 1, Interleukin-8 (precursor)
Authors:Skelton, N.J, Quan, C, Lowman, H.
Deposit date:1998-12-16
Release date:1998-12-23
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.
Structure Fold.Des., 7, 1999
6LOG
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BU of 6log by Molmil
Crystal structure of human CCL5-12AAA14 mutant
Descriptor: C-C motif chemokine 5
Authors:Chen, Y.C, Li, J.Y, Huang, C.H, Sue, S.C.
Deposit date:2020-01-05
Release date:2020-03-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:N-terminal Backbone Pairing Shifts in CCL5- 12 AAA 14 Dimer Interface: Structural Significance of the FAY Sequence.
Int J Mol Sci, 21, 2020
5WK3
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BU of 5wk3 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB
Descriptor: C-C motif chemokine 17, GLYCEROL, M116 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2017-07-24
Release date:2017-12-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into chemokine CCL17 recognition by antibody M116.
Biochem Biophys Rep, 13, 2018
8JPS
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BU of 8jps by Molmil
Structure of Duffy Antigen Receptor for Chemokines (DARC)/ACKR1 in complex with the chemokine, CCL7 (Composite map)
Descriptor: Atypical chemokine receptor 1, C-C motif chemokine 7
Authors:Banerjee, R, Khanppnavar, B, Maharana, J, Saha, S, Korkhov, V.M, Shukla, A.K.
Deposit date:2023-06-12
Release date:2024-07-31
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor.
Cell, 187, 2024
6N2U
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BU of 6n2u by Molmil
IL-8 Structure from Bacterial Expression Source
Descriptor: Interleukin-8
Authors:Park, H, Jung, J.H, Luo, J.L.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.254 Å)
Cite:IL-8 Structure from Bacterial Expression Source
To Be Published
5YAM
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BU of 5yam by Molmil
Solution structure of mice Met-CCL5/RANTES
Descriptor: C-C motif chemokine 5
Authors:Chen, Y.-C, Chen, S.-P, Lee, Y.-Z, Sue, S.-C.
Deposit date:2017-09-01
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
3IFD
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BU of 3ifd by Molmil
Human synthetic monocyte chemoattractant protein 1 (MCP-1)
Descriptor: C-C motif chemokine 2, PHOSPHATE ION, POTASSIUM ION
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2009-07-24
Release date:2009-08-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis by native chemical ligation and crystal structure of human CCL2.
Biopolymers, 94, 2010
1A15
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BU of 1a15 by Molmil
SDF-1ALPHA
Descriptor: STROMAL DERIVED FACTOR-1ALPHA, SULFATE ION
Authors:Dealwis, C.G, Fernandez, E.J, Lolis, E.
Deposit date:1997-12-22
Release date:1998-08-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor.
Proc.Natl.Acad.Sci.USA, 95, 1998
2SDF
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BU of 2sdf by Molmil
SOLUTION NMR STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), 30 STRUCTURES
Descriptor: STROMAL CELL-DERIVED FACTOR-1
Authors:Crump, M.P, Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1998-03-07
Release date:1998-06-17
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
EMBO J., 16, 1997
1CM9
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BU of 1cm9 by Molmil
CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Descriptor: PROTEIN (VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II)
Authors:Fernandez, E.J, Lolis, E.
Deposit date:1999-05-19
Release date:1999-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of the structure of vMIP-II with eotaxin-1, RANTES, and MCP-3 suggests a unique mechanism for CCR3 activation.
Biochemistry, 39, 2000
2X6L
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BU of 2x6l by Molmil
X-ray Structure of Macrophage Inflammatory Protein-1 beta
Descriptor: C-C MOTIF CHEMOKINE 4, GLYCEROL
Authors:Guo, Q, Ren, M, Tang, W.
Deposit date:2010-02-17
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.
Embo J., 29, 2010
2X6G
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BU of 2x6g by Molmil
X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A)
Descriptor: C-C MOTIF CHEMOKINE 3
Authors:Guo, Q, Ren, M, Tang, W.
Deposit date:2010-02-17
Release date:2010-11-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.
Embo J., 29, 2010

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