PDB: 36524 resultsInfo pagesStatus searchChemie searchBIRD

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9F4O	UP1 in complex with Z991506900 Descriptor: (3~{R})-3-methyl-1-(6-methylpyridin-2-yl)piperazine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Q	UP1 in complex with Z641239276 Descriptor: 5-(2-phenylethylamino)pyrimidine-2,4-diol, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4U	UP1 in complex with Z111529496 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(1~{H}-benzimidazol-2-ylmethyl)-2-methoxy-ethanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F50	UP1 in complex with Z906021418 Descriptor: 5-chloro-2-(propan-2-yl)pyrimidine-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Y	UP1 in complex with Z90120418 Descriptor: 1-(3,4,5-trimethoxyphenyl)methanamine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4V	UP1 in complex with EN300-118084 Descriptor: 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F54	UP1 in complex with EN300-197154 Descriptor: 1-methyl-3-[(3R)-piperidin-3-yl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F52	UP1 in complex with Z734147462 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, [4-(methylamino)oxan-4-yl]methanol Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5C	UP1 in complex with Z198195770 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-[3-(carbamoylamino)phenyl]acetamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F55	UP1 in complex with Z235361315 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(3-azanyl-2-methyl-phenyl)propanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5E	UP1 in complex with Z30820160 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(4-methyl-1,3-thiazol-2-yl)propanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5G	UP1 in complex with EN300-115958 Descriptor: 1-[(2R)-1-(methanesulfonyl)pyrrolidin-2-yl]methanamine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4D	UP1 in complex with Z1203107138 Descriptor: 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4G	UP1 in complex with Z1373445602 Descriptor: 4-(3-fluoranylpyridin-2-yl)-1-methyl-piperazin-2-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4H	UP1 in complex with Z106579662 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4E	UP1 in complex with Z1152242726 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(6-methoxypyridin-3-yl)-N'-thiophen-2-ylurea Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4F	UP1 in complex with Z86417414 Descriptor: 2-fluoranyl-~{N}-(1,3,4-thiadiazol-2-yl)benzamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F1S	Structure of UP1 S4ES6E phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-20 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
8Z4B	Crystal structure of LysB22-AspB28 insulin analog at ambient structure Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Ayan, E, Demirci, H. Deposit date: 2024-04-17 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of LysB22-AspB28 insulin analog at ambient structure To Be Published
9BCB	Crystal structure of human cellular retinol binding protein 3 in complex with C11 TopFluor MG Descriptor: 1-[11-(dipyrrometheneboron difluoride)undecanoyl]-rac-glycerol, GLYCEROL, Retinol-binding protein 5 Authors: Golczak, M. Deposit date: 2024-04-08 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Interactom of cellular retinol binding protein 3. To Be Published
9EWQ	Influenza virus neuraminidase N1 NC13 ectodomain with a tetrabrachio-domain stalk Descriptor: Neuraminidase Authors: Roelofs, M.C, Zeev-Ben-Mordehai, T. Deposit date: 2024-04-04 Release date: 2024-04-24 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge. Npj Vaccines, 9, 2024
8YX9	CD40 in complex with Dacetuzumab Fab Descriptor: Dacetuzumab, Heavy chain, light chain, ... Authors: Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. Deposit date: 2024-04-02 Release date: 2024-05-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochem.Biophys.Res.Commun., 714, 2024
8YX1	CD40 in complex with Bleselumab Fab Descriptor: Bleselumab, heavy chain, light chain, ... Authors: Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. Deposit date: 2024-04-01 Release date: 2024-05-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochem.Biophys.Res.Commun., 714, 2024
9B7F	S_SAD structure of HEWL using lossless default compression Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... Authors: Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. Deposit date: 2024-03-27 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
9B7E	S_SAD structure of HEWL using lossy compression data with a compression ratio of 422 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... Authors: Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. Deposit date: 2024-03-27 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published

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