5W1M
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![BU of 5w1m by Molmil](/molmil-images/mine/5w1m) | MACV GP1 CR1-07 Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | Deposit date: | 2017-06-03 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.91 Å) | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
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5W1G
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![BU of 5w1g by Molmil](/molmil-images/mine/5w1g) | CR1-07 unliganded Fab | Descriptor: | CR1-07 Fab heavy chain, CR1-07 Fab light chain | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | Deposit date: | 2017-06-03 | Release date: | 2018-05-30 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
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4IEF
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![BU of 4ief by Molmil](/molmil-images/mine/4ief) | Complex of Porphyromonas gingivalis RgpB pro- and mature domains | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BARIUM ION, CALCIUM ION, ... | Authors: | de Diego, I, Veillard, F.T, Guevara, T, Potempa, B, Sztukowska, M, Potempa, J, Gomis-Ruth, F.X. | Deposit date: | 2012-12-13 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases. J.Biol.Chem., 288, 2013
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4OD2
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![BU of 4od2 by Molmil](/molmil-images/mine/4od2) | |
4G3G
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4A3U
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6XCJ
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![BU of 6xcj by Molmil](/molmil-images/mine/6xcj) | Crystal Structure of DH650 Fab from a Rhesus Macaque in Complex with HIV-1 gp120 Core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH650 Fab Heavy Chain, DH650 Fab Light Chain, ... | Authors: | Raymond, D.D, Chug, H, Harrison, S.C. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science, 371, 2021
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2BEA
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![BU of 2bea by Molmil](/molmil-images/mine/2bea) | Crystal structure of Asn14 to Gly mutant of WCI | Descriptor: | Chymotrypsin inhibitor 3 | Authors: | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | Deposit date: | 2005-10-24 | Release date: | 2006-06-13 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
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4NB6
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![BU of 4nb6 by Molmil](/molmil-images/mine/4nb6) | Crystal structure of the ligand binding domain of RORC with T0901317 | Descriptor: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma | Authors: | Hymowitz, S.G, Boenig-de Leon, G. | Deposit date: | 2013-10-22 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc. Bioorg.Med.Chem.Lett., 23, 2013
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4OTF
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![BU of 4otf by Molmil](/molmil-images/mine/4otf) | Crystal structure of the kinase domain of Bruton's Tyrosine kinase with GDC0834 | Descriptor: | N-{3-[6-({4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl }-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide, SULFATE ION, Tyrosine-protein kinase BTK | Authors: | Hymowitz, S.G, Maurer, B. | Deposit date: | 2014-02-13 | Release date: | 2015-01-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834. Bioorg.Med.Chem.Lett., 25, 2015
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4G3E
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4G3F
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3MXV
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![BU of 3mxv by Molmil](/molmil-images/mine/3mxv) | |
3MXW
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2BBF
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![BU of 2bbf by Molmil](/molmil-images/mine/2bbf) | Crystal structure of tRNA-guanine transglycosylase (TGT) from Zymomonas mobilis in complex with 6-amino-3,7-dihydro-imidazo[4,5-g]quinazolin-8-one | Descriptor: | 6-AMINO-3,7-DIHYDRO-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ZINC ION, tRNA guanine transglycosylase | Authors: | Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G. | Deposit date: | 2005-10-17 | Release date: | 2007-04-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding. J.Mol.Biol., 370, 2007
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2QII
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![BU of 2qii by Molmil](/molmil-images/mine/2qii) | Crystal Structure Of tRNA-Guanine Transglycosylase (TGT) From Zymomonas mobilis Complexed With Archaeosine Precursor, Preq0 | Descriptor: | 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | Authors: | Tidten, N, Brenk, R, Heine, A, Reuter, K, Klebe, G. | Deposit date: | 2007-07-04 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies. J.Mol.Biol., 374, 2007
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2LT5
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![BU of 2lt5 by Molmil](/molmil-images/mine/2lt5) | Zymogen-FLG of the onconase | Descriptor: | Protein P-30 | Authors: | Vilanova, M, Callis, M, Laurents, D.V, Ribo, M, Bruix, M, Serrano, S. | Deposit date: | 2012-05-14 | Release date: | 2012-10-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: |
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2HEV
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![BU of 2hev by Molmil](/molmil-images/mine/2hev) | Crystal structure of the complex between OX40L and OX40 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4 | Authors: | Hymowitz, S.G, Compaan, D.M. | Deposit date: | 2006-06-22 | Release date: | 2006-08-29 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | The Crystal Structure of the Costimulatory OX40-OX40L Complex. Structure, 14, 2006
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2HFG
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![BU of 2hfg by Molmil](/molmil-images/mine/2hfg) | Crystal structure of hBR3 bound to CB3s-Fab | Descriptor: | CB3s Fab heavy chain, CB3s Fab light chain (kappa), Tumor necrosis factor receptor superfamily member 13C | Authors: | Hymowitz, S.G. | Deposit date: | 2006-06-23 | Release date: | 2006-11-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells. Blood, 108, 2006
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2HEW
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![BU of 2hew by Molmil](/molmil-images/mine/2hew) | The X-ray crystal structure of murine OX40L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Tumor necrosis factor ligand superfamily member 4 | Authors: | Hymowitz, S.G, Compaan, D.M. | Deposit date: | 2006-06-22 | Release date: | 2006-08-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Crystal Structure of the Costimulatory OX40-OX40L Complex. Structure, 14, 2006
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2H9G
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2HEY
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![BU of 2hey by Molmil](/molmil-images/mine/2hey) | Crystal structure of murine OX40L bound to human OX40 | Descriptor: | SULFATE ION, Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4 | Authors: | Hymowitz, S.G. | Deposit date: | 2006-06-22 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of the Costimulatory OX40-OX40L Complex. Structure, 14, 2006
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3LN4
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![BU of 3ln4 by Molmil](/molmil-images/mine/3ln4) | Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2 | Descriptor: | 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ... | Authors: | Theodossis, A, Gras, S, Rossjohn, J. | Deposit date: | 2010-02-01 | Release date: | 2010-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.296 Å) | Cite: | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
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3LN5
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![BU of 3ln5 by Molmil](/molmil-images/mine/3ln5) | Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase | Descriptor: | 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Theodossis, A, Gras, S, Rossjohn, J. | Deposit date: | 2010-02-02 | Release date: | 2010-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
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2HFF
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![BU of 2hff by Molmil](/molmil-images/mine/2hff) | Crystal structure of CB2 Fab | Descriptor: | CB2 Fab, heavy chain, light chain | Authors: | Hymowitz, S.G. | Deposit date: | 2006-06-23 | Release date: | 2006-11-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells. Blood, 108, 2006
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