8QL3
 
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 233 fs structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL6
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 25 ps structure | | Descriptor: | Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL8
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 125 ps structure | | Descriptor: | Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL7
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 35 ps structure | | Descriptor: | Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL5
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 1 ps structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL4
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 349 fs structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QEA
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 96 fs structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-08-31 | | Release date: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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6H9B
 | | 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation | | Descriptor: | 9-methyl-3-[1-(2-methylquinolin-4-yl)ethenyl]carbazole, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Varela, P.F, Gigant, B. | | Deposit date: | 2018-08-03 | | Release date: | 2018-12-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
J. Med. Chem., 62, 2019
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8QL2
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: dark structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QL9
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 1 ns structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8QLA
 | | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution: 10 ns structure | | Descriptor: | Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Weinert, T, Wranik, M, Seidel, H.-P, Church, J, Steinmetz, M.O, Schapiro, I, Standfuss, J. | | Deposit date: | 2023-09-19 | | Release date: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ultrafast structural transitions in an azobenzene photoswitch at near-atomic resolution
To Be Published
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8R6O
 | | Tubulin-4AZA2996 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Detyrosinated tubulin alpha-1B chain, ... | | Authors: | Herman, J, Vanstreels, E, Bardiot, D, Prota, A.E, Olieric, N, Gao, L.-J, Vercruysse, T, Daems, T, Waer, M, Herdewijn, P, Louat, T, Steinmetz, M.O, De Jonghe, S, Sprangers, B, Daelemans, D. | | Deposit date: | 2023-11-22 | | Release date: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | 3-nitropyridine analogues as novel microtubule-targeting agents.
Plos One, 19, 2024
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3IZ0
 | | Human Ndc80 Bonsai Decorated Microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Alushin, G.M, Ramey, V.H, Pasqualato, S, Ball, D.A, Grigorieff, N, Musacchio, A, Nogales, E. | | Deposit date: | 2010-08-09 | | Release date: | 2010-10-13 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | The Ndc80 kinetochore complex forms oligomeric arrays along microtubules.
Nature, 467, 2010
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3J6H
 | | Nucleotide-free Kinesin motor domain complexed with GMPCPP-microtubule | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin heavy chain isoform 5C, MAGNESIUM ION, ... | | Authors: | Morikawa, M, Yajima, H, Nitta, R, Inoue, S, Ogura, T, Sato, C, Hirokawa, N. | | Deposit date: | 2014-02-21 | | Release date: | 2015-04-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (8.1 Å) | | Cite: | X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
Embo J., 2015
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3J1T
 | | High affinity dynein microtubule binding domain - tubulin complex | | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | | Deposit date: | 2012-06-25 | | Release date: | 2012-09-26 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.7 Å) | | Cite: | Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
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3J6E
 | | Energy minimized average structure of Microtubules stabilized by GmpCpp | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | Deposit date: | 2014-02-18 | | Release date: | 2014-06-04 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3J6F
 | | Minimized average structure of GDP-bound dynamic microtubules | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | Deposit date: | 2014-02-19 | | Release date: | 2014-06-04 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3JAS
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3JAT
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3J6G
 | | Minimized average structure of microtubules stabilized by taxol | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | Deposit date: | 2014-02-19 | | Release date: | 2014-06-04 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3J7I
 | | Structure of alpha- and beta- tubulin in GMPCPP-microtubules | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin alpha-1A chain, ... | | Authors: | Yajima, H, Ogura, T, Nitta, R, Okada, Y, Sato, C, Hirokawa, N. | | Deposit date: | 2014-07-01 | | Release date: | 2014-12-10 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy
J.Cell Biol., 198, 2012
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3JAR
 | | Cryo-EM structure of GDP-microtubule co-polymerized with EB3 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Zhang, R, Nogales, E. | | Deposit date: | 2015-06-19 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
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3JAW
 | | Atomic model of a microtubule seam based on a cryo-EM reconstruction of the EB3-bound microtubule (merged dataset containing tubulin bound to GTPgammaS, GMPCPP, and GDP) | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Zhang, R, Nogales, E. | | Deposit date: | 2015-06-30 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
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3J1U
 | | Low affinity dynein microtubule binding domain - tubulin complex | | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | | Deposit date: | 2012-06-25 | | Release date: | 2012-09-26 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.7 Å) | | Cite: | Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
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3J6P
 | | Pseudo-atomic model of dynein microtubule binding domain-tubulin complex based on a cryoEM map | | Descriptor: | Dynein heavy chain, cytoplasmic, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Uchimura, S, Fujii, T, Takazaki, H, Ayukawa, R, Nishikawa, Y, Minoura, I, Hachikubo, Y, Kurisu, G, Sutoh, K, Kon, T, Namba, K, Muto, E. | | Deposit date: | 2014-03-20 | | Release date: | 2014-12-31 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | A flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activation
J.Cell Biol., 208, 2015
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