5N8Z
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![BU of 5n8z by Molmil](/molmil-images/mine/5n8z) | Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCCTT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*TP*T)-3'), ... | Authors: | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.477 Å) | Cite: | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N8U
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![BU of 5n8u by Molmil](/molmil-images/mine/5n8u) | Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*T)-3'), ... | Authors: | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N9E
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![BU of 5n9e by Molmil](/molmil-images/mine/5n9e) | Crystal Structure of Drosophila DHX36 helicase in complex with TGGGGATTT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*TP*GP*GP*GP*GP*AP*TP*TP*T)-3') | Authors: | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.007 Å) | Cite: | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5LST
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![BU of 5lst by Molmil](/molmil-images/mine/5lst) | Crystal structure of the human RecQL4 helicase. | Descriptor: | ATP-dependent DNA helicase Q4, ZINC ION | Authors: | Kaiser, S, Sauer, F, Kisker, C. | Deposit date: | 2016-09-05 | Release date: | 2017-07-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism. Nat Commun, 8, 2017
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5M5P
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![BU of 5m5p by Molmil](/molmil-images/mine/5m5p) | S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8 | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | Authors: | Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. | Deposit date: | 2016-10-22 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
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5N90
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![BU of 5n90 by Molmil](/molmil-images/mine/5n90) | Crystal Structure of Drosophila DHX36 helicase in complex with TTGTGGTGT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*TP*TP*GP*TP*GP*GP*TP*GP*T)-3'), ... | Authors: | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.069 Å) | Cite: | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N8S
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![BU of 5n8s by Molmil](/molmil-images/mine/5n8s) | Crystal Structure of Drosophila DHX36 helicase in complex with polyT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | Authors: | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N96
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![BU of 5n96 by Molmil](/molmil-images/mine/5n96) | Crystal Structure of Drosophila DHX36 helicase in complex with AGGGTTTTTT | Descriptor: | CG9323, isoform A, DNA (5'-D(P*AP*GP*GP*GP*TP*TP*TP*TP*TP*T)-3'), ... | Authors: | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | Deposit date: | 2017-02-24 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.716 Å) | Cite: | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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6CRM
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![BU of 6crm by Molmil](/molmil-images/mine/6crm) | |
6CZ5
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![BU of 6cz5 by Molmil](/molmil-images/mine/6cz5) | Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C | Descriptor: | 5'-O-[(R)-hydroxy(propanoylamino)phosphoryl]adenosine, ATP-dependent RNA helicase DDX3X | Authors: | Barkovich, K.J, Moore, M.K, Hu, Q, Shokat, K.M. | Deposit date: | 2018-04-08 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Chemical genetic inhibition of DEAD-box proteins using covalent complementarity. Nucleic Acids Res., 46, 2018
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6D6R
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![BU of 6d6r by Molmil](/molmil-images/mine/6d6r) | |
6ZM2
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![BU of 6zm2 by Molmil](/molmil-images/mine/6zm2) | |
6ZWX
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![BU of 6zwx by Molmil](/molmil-images/mine/6zwx) | Crystal structure of E. coli RNA helicase HrpA | Descriptor: | ATP-dependent RNA helicase HrpA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-07-29 | Release date: | 2021-06-30 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
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6ZWW
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![BU of 6zww by Molmil](/molmil-images/mine/6zww) | Crystal structure of E. coli RNA helicase HrpA in complex with RNA | Descriptor: | ATP-dependent RNA helicase HrpA, CALCIUM ION, ssRNA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-07-29 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
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7A8R
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![BU of 7a8r by Molmil](/molmil-images/mine/7a8r) | Structure of RecQL from Bos taurus | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, MAGNESIUM ION, ... | Authors: | Rety, S, Chen, W.F, Xi, X.G. | Deposit date: | 2020-08-30 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers. Cell Rep, 36, 2021
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7AUD
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![BU of 7aud by Molmil](/molmil-images/mine/7aud) | |
7AUC
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![BU of 7auc by Molmil](/molmil-images/mine/7auc) | |
7AQO
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![BU of 7aqo by Molmil](/molmil-images/mine/7aqo) | yeast THO-Sub2 complex dimer | Descriptor: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-22 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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7APX
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![BU of 7apx by Molmil](/molmil-images/mine/7apx) | yeast THO-Sub2 complex | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-20 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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7APK
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![BU of 7apk by Molmil](/molmil-images/mine/7apk) | Structure of the human THO - UAP56 complex | Descriptor: | Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... | Authors: | Hohmann, U, Puehringer, T, Plaschka, C. | Deposit date: | 2020-10-17 | Release date: | 2020-12-16 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
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7ASK
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![BU of 7ask by Molmil](/molmil-images/mine/7ask) | 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60 | Authors: | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | Deposit date: | 2020-10-27 | Release date: | 2021-04-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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7AKP
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![BU of 7akp by Molmil](/molmil-images/mine/7akp) | Crystal structure of E. coli RNA helicase HrpA-D305A | Descriptor: | ATP-dependent RNA helicase HrpA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-10-01 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
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6ZNS
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![BU of 6zns by Molmil](/molmil-images/mine/6zns) | Crystal Structure of DUF1998 helicase MrfA | Descriptor: | Uncharacterized ATP-dependent helicase YprA, ZINC ION | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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6ZNP
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![BU of 6znp by Molmil](/molmil-images/mine/6znp) | Crystal Structure of DUF1998 helicase MrfA bound to DNA | Descriptor: | CITRIC ACID, Uncharacterized ATP-dependent helicase YprA, ZINC ION, ... | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2021-01-20 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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6ZNQ
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![BU of 6znq by Molmil](/molmil-images/mine/6znq) | Crystal Structure of DUF1998 helicase MrfA bound to DNA and AMPPNP | Descriptor: | CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Uncharacterized ATP-dependent helicase YprA, ... | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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