2H7J
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![BU of 2h7j by Molmil](/molmil-images/mine/2h7j) | Crystal Structure of Cathepsin S in complex with a Nonpeptidic Inhibitor. | Descriptor: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Cathepsin S, N-[(1S)-1-{1-[(1R,3E)-1-ACETYLPENT-3-EN-1-YL]-1H-1,2,3-TRIAZOL-4-YL}-1,2-DIMETHYLPROPYL]BENZAMIDE | Authors: | Patterson, A.W, Wood, W.J, Hornsby, M, Lesley, S, Spraggon, G, Ellman, J.A. | Deposit date: | 2006-06-02 | Release date: | 2006-10-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method. J.Med.Chem., 49, 2006
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2H7O
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![BU of 2h7o by Molmil](/molmil-images/mine/2h7o) | Crystal structure of the Rho-GTPase binding domain of YpkA | Descriptor: | Protein kinase ypkA | Authors: | Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E. | Deposit date: | 2006-06-02 | Release date: | 2006-09-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors. Cell(Cambridge,Mass.), 126, 2006
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2H7Q
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![BU of 2h7q by Molmil](/molmil-images/mine/2h7q) | Cytochrome P450cam complexed with imidazole | Descriptor: | Cytochrome P450-cam, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Verras, A, Alian, A, Montellano, P.R. | Deposit date: | 2006-06-02 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation. Protein Eng.Des.Sel., 19, 2006
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2H7R
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2H7S
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![BU of 2h7s by Molmil](/molmil-images/mine/2h7s) | L244A mutant of Cytochrome P450cam | Descriptor: | Cytochrome P450-cam, HEME C | Authors: | Verras, A, Alian, A, Montellano, P.R. | Deposit date: | 2006-06-02 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation. Protein Eng.Des.Sel., 19, 2006
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2H7T
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![BU of 2h7t by Molmil](/molmil-images/mine/2h7t) | |
2H7V
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![BU of 2h7v by Molmil](/molmil-images/mine/2h7v) | Co-crystal structure of YpkA-Rac1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Migration-inducing protein 5, ... | Authors: | Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E. | Deposit date: | 2006-06-04 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors. Cell(Cambridge,Mass.), 126, 2006
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2H7W
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2H7X
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![BU of 2h7x by Molmil](/molmil-images/mine/2h7x) | Pikromycin Thioesterase adduct with reduced triketide affinity label | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A. | Deposit date: | 2006-06-05 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels NAT.CHEM.BIOL., 2, 2006
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2H7Y
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![BU of 2h7y by Molmil](/molmil-images/mine/2h7y) | Pikromycin Thioesterase with covalent affinity label | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A. | Deposit date: | 2006-06-06 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels NAT.CHEM.BIOL., 2, 2006
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2H7Z
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![BU of 2h7z by Molmil](/molmil-images/mine/2h7z) | Crystal structure of irditoxin | Descriptor: | Irditoxin subunit A, Irditoxin subunit B | Authors: | Pawlak, J, Kini, R.M, Stura, E.A, Le Du, M.H. | Deposit date: | 2006-06-06 | Release date: | 2006-08-29 | Last modified: | 2011-10-05 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity. Faseb J., 23, 2009
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2H80
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![BU of 2h80 by Molmil](/molmil-images/mine/2h80) | NMR structures of SAM domain of Deleted in Liver Cancer 2 (DLC2) | Descriptor: | StAR-related lipid transfer protein 13 | Authors: | Li, H.Y, Fung, K.L, Jin, D.Y, Chung, S.S, Ko, B.C, Sun, H.Z. | Deposit date: | 2006-06-06 | Release date: | 2007-05-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures, dynamics, and lipid-binding of the sterile alpha-motif domain of the deleted in liver cancer 2 Proteins, 67, 2007
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2H84
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![BU of 2h84 by Molmil](/molmil-images/mine/2h84) | Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium) | Descriptor: | HEXAETHYLENE GLYCOL, Steely1 | Authors: | Austin, M.B, Saito, T, Bowman, M.E, Haydock, S, Kato, A, Moore, B.S, Kay, R.R, Noel, J.P. | Deposit date: | 2006-06-06 | Release date: | 2006-08-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Nat.Chem.Biol., 2, 2006
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2H85
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![BU of 2h85 by Molmil](/molmil-images/mine/2h85) | Crystal Structure of Nsp 15 from SARS | Descriptor: | Putative orf1ab polyprotein | Authors: | Ricagno, S, Egloff, M.P, Ulferts, R, Coutard, B, Nurizzo, D, Campanacci, V, Cambillau, C, Ziebuhr, J, Canard, B. | Deposit date: | 2006-06-06 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H88
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![BU of 2h88 by Molmil](/molmil-images/mine/2h88) | Avian Mitochondrial Respiratory Complex II at 1.8 Angstrom Resolution | Descriptor: | AZIDE ION, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Huang, L.S, Shen, J.T, Wang, A.C, Berry, E.A. | Deposit date: | 2006-06-06 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the Biochim.Biophys.Acta, 1757
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2H89
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![BU of 2h89 by Molmil](/molmil-images/mine/2h89) | Avian Respiratory Complex II with Malonate Bound | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Huang, L.S, Shen, J.T, Wang, A.C, Berry, E.A. | Deposit date: | 2006-06-06 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the Biochim.Biophys.Acta, 1757
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2H8A
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2H8B
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![BU of 2h8b by Molmil](/molmil-images/mine/2h8b) | Solution structure of INSL3 | Descriptor: | Insulin-like 3 | Authors: | Rosengren, K.J, Craik, D.J, Daly, N.L. | Deposit date: | 2006-06-07 | Release date: | 2006-08-01 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Solution Structure and Characterization of the LGR8 Receptor Binding Surface of Insulin-like Peptide 3 J.Biol.Chem., 281, 2006
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2H8C
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![BU of 2h8c by Molmil](/molmil-images/mine/2h8c) | Structure of RusA D70N in complex with DNA | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3', Crossover junction endodeoxyribonuclease rusA | Authors: | Macmaster, R.A. | Deposit date: | 2006-06-07 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity. Nucleic Acids Res., 34, 2006
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2H8D
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![BU of 2h8d by Molmil](/molmil-images/mine/2h8d) | Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 8.4 | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, POTASSIUM ION, ... | Authors: | Mazzarella, L, Vergara, A, Vitagliano, L, Merlino, A, Bonomi, G, Scala, S, Verde, C, di Prisco, G. | Deposit date: | 2006-06-07 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect. Proteins, 65, 2006
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2H8E
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![BU of 2h8e by Molmil](/molmil-images/mine/2h8e) | Structure RusA D70N | Descriptor: | Crossover junction endodeoxyribonuclease rusA | Authors: | Macmaster, R.A. | Deposit date: | 2006-06-07 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity. Nucleic Acids Res., 34, 2006
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2H8F
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![BU of 2h8f by Molmil](/molmil-images/mine/2h8f) | Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2 | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mazzarella, L, Vergara, A, Vitagliano, L, Merlino, A, Bonomi, G, Scala, S, Verde, C, di Prisco, G. | Deposit date: | 2006-06-07 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect. Proteins, 65, 2006
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2H8G
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![BU of 2h8g by Molmil](/molmil-images/mine/2h8g) | 5'-Methylthioadenosine Nucleosidase from Arabidopsis thaliana | Descriptor: | 5'-Methylthioadenosine Nucleosidase, ADENINE | Authors: | Park, E.Y, Oh, S.I, Nam, M.J, Shin, J.S, Kim, K.N, Song, H.K. | Deposit date: | 2006-06-07 | Release date: | 2006-10-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana at 1.5-A resolution Proteins, 65, 2006
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2H8H
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![BU of 2h8h by Molmil](/molmil-images/mine/2h8h) | Src kinase in complex with a quinazoline inhibitor | Descriptor: | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src | Authors: | Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. | Deposit date: | 2006-06-07 | Release date: | 2006-11-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006
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2H8I
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![BU of 2h8i by Molmil](/molmil-images/mine/2h8i) | |