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6V0K
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BU of 6v0k by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain
Descriptor: GLYCEROL, Terpene synthase
Authors:Christianson, D.W, Ronnebaum, T.A.
Deposit date:2019-11-18
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Higher-order oligomerization of a chimeric alpha beta gamma bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent.
J.Struct.Biol., 210, 2020
6VJC
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BU of 6vjc by Molmil
LmFPPS mutant T164Y in complex with 476A, IPP & Ca
Descriptor: 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ...
Authors:Maheshwari, S, Kim, Y.S, Aripirala, S, Gabelli, S.B.
Deposit date:2020-01-15
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
6W7I
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BU of 6w7i by Molmil
LmFPPS mutant T164W in complex with 476A, IPP & Ca
Descriptor: 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ...
Authors:Maheshwari, S, Kim, Y.S, Aripirala, S, Gabelli, S.B.
Deposit date:2020-03-19
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
7BUX
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Eucommia ulmoides FPS1
Descriptor: FPS2
Authors:Kajiura, H, Yoshizawa, T, Tokumoto, Y, Suzuki, N, Takeno, S, Takeno, K.J, Yamashita, T, Tanaka, S, Kaneko, Y, Fujiyama, K, Matsumura, H, Nakazawa, Y.
Deposit date:2020-04-08
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis.
Commun Biol, 4, 2021
7BUW
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Eucommia ulmoides TPT3 mutant -C94Y/A95F
Descriptor: FPS3
Authors:Kajiura, H, Yoshizawa, T, Tokumoto, Y, Suzuki, N, Takeno, S, Takeno, K.J, Yamashita, T, Tanaka, S, Kaneko, Y, Fujiyama, K, Matsumura, H, Nakazawa, Y.
Deposit date:2020-04-08
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis.
Commun Biol, 4, 2021
7BUV
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Eucommia ulmoides TPT3, crystal form 2
Descriptor: FPS3
Authors:Kajiura, H, Yoshizawa, T, Tokumoto, Y, Suzuki, N, Takeno, S, Takeno, K.J, Yamashita, T, Tanaka, S, Kaneko, Y, Fujiyama, K, Matsumura, H, Nakazawa, Y.
Deposit date:2020-04-08
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis.
Commun Biol, 4, 2021
7BUU
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BU of 7buu by Molmil
Eucommia ulmoides TPT3, crystal form 1
Descriptor: FPS3
Authors:Kajiura, H, Yoshizawa, T, Tokumoto, Y, Suzuki, N, Takeno, S, Takeno, K.J, Yamashita, T, Tanaka, S, Kaneko, Y, Fujiyama, K, Matsumura, H, Nakazawa, Y.
Deposit date:2020-04-08
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis.
Commun Biol, 4, 2021
6WW1
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BU of 6ww1 by Molmil
Crystal structure of the LmFPPS mutant E97Y
Descriptor: 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ...
Authors:Maheshwari, S, Kim, Y.S, Gabelli, S.B.
Deposit date:2020-05-07
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
7JTH
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BU of 7jth by Molmil
Cryo-EM structure of unliganded octameric prenyltransferase domain of Phomopsis amygdali fusicoccadiene synthase
Descriptor: Fusicoccadiene synthase
Authors:Faylo, J.L, van Eeuwen, T, Murakami, K, Christianson, D.W.
Deposit date:2020-08-17
Release date:2021-04-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insight on assembly-line catalysis in terpene biosynthesis.
Nat Commun, 12, 2021
7LBJ
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Crystal structure of octaprenyl diphosphate synthase from Stenotrophomonas maltophilia
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Geranyltranstransferase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-01-08
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of octaprenyl diphosphate synthase from Stenotrophomonas maltophilia
to be published
7MXZ
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BU of 7mxz by Molmil
Sy-CrtE apo structure
Descriptor: CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-19
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY1
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BU of 7my1 by Molmil
Sy-CrtE structure with IPP, N-term His-tag
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, ...
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-19
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY0
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BU of 7my0 by Molmil
Sy-CrtE IPP structure
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ...
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-19
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY6
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BU of 7my6 by Molmil
Se-CrtE C-term His-tag with IPP added
Descriptor: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ...
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY7
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BU of 7my7 by Molmil
Se-CrtE N-term His-tag structure
Descriptor: Farnesyl-diphosphate synthase
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-20
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7S0M
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BU of 7s0m by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723T, bound with non-productive isopentenyl diphosphate
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Terpene synthase
Authors:Ronnebaum, T.A, Christianson, D.W.
Deposit date:2021-08-30
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase.
Biochemistry, 60, 2021
7S0A
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BU of 7s0a by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, H786A
Descriptor: Terpene synthase
Authors:Ronnebaum, T.A, Christianson, D.W.
Deposit date:2021-08-30
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase.
Biochemistry, 60, 2021
7S0H
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BU of 7s0h by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723Y
Descriptor: Terpene synthase
Authors:Ronnebaum, T.A, Christianson, D.W.
Deposit date:2021-08-30
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase.
Biochemistry, 60, 2021
7S09
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BU of 7s09 by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, F760A
Descriptor: Terpene synthase
Authors:Ronnebaum, T.A, Christianson, D.W.
Deposit date:2021-08-30
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase.
Biochemistry, 60, 2021
7S0L
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BU of 7s0l by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723F
Descriptor: Terpene synthase
Authors:Ronnebaum, T.A, Christianson, D.W.
Deposit date:2021-08-30
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase.
Biochemistry, 60, 2021
7WIJ
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BU of 7wij by Molmil
Cryo-EM structure of prenyltransferase domain of Macrophoma phaseolina macrophomene synthase
Descriptor: Geranylgeranyl diphosphate synthase
Authors:Mori, T, Adachi, N, Abe, I.
Deposit date:2022-01-03
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Discovery of non-squalene triterpenes.
Nature, 606, 2022
8A7C
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BU of 8a7c by Molmil
PcIDS1 in complex with Mg2+, IPP, and ZOL
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ...
Authors:Ecker, F, Boland, W, Groll, M.
Deposit date:2022-06-20
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023
8A6Z
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BU of 8a6z by Molmil
PcIDS1 in complex with Mn2+ and IPP
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ...
Authors:Ecker, F, Boland, W, Groll, M.
Deposit date:2022-06-20
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023
8A7A
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BU of 8a7a by Molmil
PcIDS1 in complex with Mg2+ and 3-Br-GPP
Descriptor: Isoprenyl diphosphate synthase, MAGNESIUM ION, [(2Z)-3-bromanyl-7-methyl-octa-2,6-dienyl] phosphono hydrogen phosphate
Authors:Ecker, F, Boland, W, Groll, M.
Deposit date:2022-06-20
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023
8A6U
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BU of 8a6u by Molmil
PcIDS1 in complex with Mg2+
Descriptor: Isoprenyl diphosphate synthase, MAGNESIUM ION
Authors:Ecker, F, Boland, W, Groll, M.
Deposit date:2022-06-20
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023

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